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Article: Salvage of recurrent head and neck squamous cell carcinoma after primary curative surgery
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TitleSalvage of recurrent head and neck squamous cell carcinoma after primary curative surgery
 
AuthorsWong, LY1
Wei, WI1
Lam, LK1
Yuen, APW1
 
KeywordsCarcinoma
Head
Neck
Recurrence
Salvage
 
Issue Date2003
 
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
 
CitationHead And Neck, 2003, v. 25 n. 11, p. 953-959 [How to Cite?]
DOI: http://dx.doi.org/10.1002/hed.10310
 
AbstractPurpose. The efficacy of salvage treatment of recurrent head and neck squamous cell carcinomas (HNSCC) after primary curative surgery was evaluated. Methods. The management outcome of 377 patients who had recurrent squamous cell carcinoma of oral cavity, oropharynx, hypopharynx, and larynx after primary curative surgery was reviewed. Results. The surgical salvage rates of recurrence were 29% local, 30% tracheostomal, 56% unilateral nodal recurrence of previously undissected neck, 32% of unilateral neck recurrence after prior neck dissection, and 11% lung metastasis. The 5-year tumor-free actuarial survival rates of those patients who received surgical salvage was 35% for local recurrence, 32% for unilateral nodal recurrence of the previously undissected neck, and 18% for nodal recurrence of the previously dissected neck. One patient of six with tracheostomal recurrence salvaged with surgery and one patient of six with lung metastasis salvaged with lobectomy survived without tumor at 5 years. There was no 5-year survivor of all patients salvaged with other nonsurgical methods. The mean survival of patients without surgical salvage was 6 months. Conclusions. There was a moderate chance of cure after surgical salvage of locoregional recurrent HNSCC. Surgical salvage was, however, only feasible for early recurrent tumor. Close follow-up surveillance of early recurrence is essential after primary treatment of patients. © 2003 Wiley Periodicals, Inc.
 
ISSN1043-3074
2013 Impact Factor: 3.006
 
DOIhttp://dx.doi.org/10.1002/hed.10310
 
ISI Accession Number IDWOS:000186160500009
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorWong, LY
 
dc.contributor.authorWei, WI
 
dc.contributor.authorLam, LK
 
dc.contributor.authorYuen, APW
 
dc.date.accessioned2010-09-06T08:53:03Z
 
dc.date.available2010-09-06T08:53:03Z
 
dc.date.issued2003
 
dc.description.abstractPurpose. The efficacy of salvage treatment of recurrent head and neck squamous cell carcinomas (HNSCC) after primary curative surgery was evaluated. Methods. The management outcome of 377 patients who had recurrent squamous cell carcinoma of oral cavity, oropharynx, hypopharynx, and larynx after primary curative surgery was reviewed. Results. The surgical salvage rates of recurrence were 29% local, 30% tracheostomal, 56% unilateral nodal recurrence of previously undissected neck, 32% of unilateral neck recurrence after prior neck dissection, and 11% lung metastasis. The 5-year tumor-free actuarial survival rates of those patients who received surgical salvage was 35% for local recurrence, 32% for unilateral nodal recurrence of the previously undissected neck, and 18% for nodal recurrence of the previously dissected neck. One patient of six with tracheostomal recurrence salvaged with surgery and one patient of six with lung metastasis salvaged with lobectomy survived without tumor at 5 years. There was no 5-year survivor of all patients salvaged with other nonsurgical methods. The mean survival of patients without surgical salvage was 6 months. Conclusions. There was a moderate chance of cure after surgical salvage of locoregional recurrent HNSCC. Surgical salvage was, however, only feasible for early recurrent tumor. Close follow-up surveillance of early recurrence is essential after primary treatment of patients. © 2003 Wiley Periodicals, Inc.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationHead And Neck, 2003, v. 25 n. 11, p. 953-959 [How to Cite?]
DOI: http://dx.doi.org/10.1002/hed.10310
 
dc.identifier.doihttp://dx.doi.org/10.1002/hed.10310
 
dc.identifier.epage959
 
dc.identifier.hkuros85403
 
dc.identifier.isiWOS:000186160500009
 
dc.identifier.issn1043-3074
2013 Impact Factor: 3.006
 
dc.identifier.issue11
 
dc.identifier.openurl
 
dc.identifier.pmid14603456
 
dc.identifier.scopuseid_2-s2.0-0142219850
 
dc.identifier.spage953
 
dc.identifier.urihttp://hdl.handle.net/10722/84446
 
dc.identifier.volume25
 
dc.languageeng
 
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/38137
 
dc.publisher.placeUnited States
 
dc.relation.ispartofHead and Neck
 
dc.relation.referencesReferences in Scopus
 
dc.subjectCarcinoma
 
dc.subjectHead
 
dc.subjectNeck
 
dc.subjectRecurrence
 
dc.subjectSalvage
 
dc.titleSalvage of recurrent head and neck squamous cell carcinoma after primary curative surgery
 
dc.typeArticle
 
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<description.abstract>Purpose. The efficacy of salvage treatment of recurrent head and neck squamous cell carcinomas (HNSCC) after primary curative surgery was evaluated. Methods. The management outcome of 377 patients who had recurrent squamous cell carcinoma of oral cavity, oropharynx, hypopharynx, and larynx after primary curative surgery was reviewed. Results. The surgical salvage rates of recurrence were 29% local, 30% tracheostomal, 56% unilateral nodal recurrence of previously undissected neck, 32% of unilateral neck recurrence after prior neck dissection, and 11% lung metastasis. The 5-year tumor-free actuarial survival rates of those patients who received surgical salvage was 35% for local recurrence, 32% for unilateral nodal recurrence of the previously undissected neck, and 18% for nodal recurrence of the previously dissected neck. One patient of six with tracheostomal recurrence salvaged with surgery and one patient of six with lung metastasis salvaged with lobectomy survived without tumor at 5 years. There was no 5-year survivor of all patients salvaged with other nonsurgical methods. The mean survival of patients without surgical salvage was 6 months. Conclusions. There was a moderate chance of cure after surgical salvage of locoregional recurrent HNSCC. Surgical salvage was, however, only feasible for early recurrent tumor. Close follow-up surveillance of early recurrence is essential after primary treatment of patients. &#169; 2003 Wiley Periodicals, Inc.</description.abstract>
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Author Affiliations
  1. Queen Mary Hospital Hong Kong