File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Outcomes of surgery for mid and distal rectal cancer in the elderly

TitleOutcomes of surgery for mid and distal rectal cancer in the elderly
Authors
Issue Date2006
PublisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/
Citation
World Journal Of Surgery, 2006, v. 30 n. 4, p. 598-604 How to Cite?
AbstractBackground: This study aimed to evaluate the surgical strategies, operative results, and oncological outcomes of elderly patients who underwent curative resection for mid and distal rectal cancer. Comparison was made with patients of younger age. Study Design: Of the 612 patients who underwent curative resection for rectal cancer, 133 were older than 75 years of age. Comparisons were made between the young and elderly patients in the aspects of operative strategies, operative results, and long-term outcomes. Results: Resection resulting in a permanent end colostomy was performed in 96 patients (15.7%), and there was no difference between young and elderly patients. There was a female predominance in the elderly group. Elderly patients also had a higher incidence of comorbid medical diseases, especially cardiovascular and neurological diseases. The operative time, blood loss, and incidence of intraoperative complications did not differ in the two groups. However, significantly fewer elderly patients underwent adjuvant radiation and/or chemotherapy. The overall 30-day mortality was 1.14%. There was no difference between the elderly patients and younger patients in hospital mortality (P = 0.178). The complication rates of the elderly and young patients were 36.8% and 30.1%, respectively (P = 0.141). Comparison between the individual complications in the elderly and young patients revealed significantly more cardiovascular complications in the elderly patients. With the median follow up of the surviving patients of 45.1 months, the overall 5-year survival of the elderly and younger groups was 47.7% and 70.1%, respectively (P < 0.001). The 5-year cancer-specific survival was 75.4% and 67.5% in the young and elderly patients, respectively (P = 0.061). Conclusions: Curative resection for mid and distal rectal cancer for the elderly can be performed safely with the same strategies of sphincter preservation used for younger patients. The postoperative complications and the 5-year cancer-specific survival rates were similar to those of younger patients. © 2006 by the Société Internationale de Chirurgie.
Persistent Identifierhttp://hdl.handle.net/10722/84343
ISSN
2015 Impact Factor: 2.523
2015 SCImago Journal Rankings: 1.375
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWai, LLen_HK
dc.contributor.authorHok, KCen_HK
dc.contributor.authorHo, JWCen_HK
dc.contributor.authorYee, MLen_HK
dc.contributor.authorChi, LSen_HK
dc.date.accessioned2010-09-06T08:51:49Z-
dc.date.available2010-09-06T08:51:49Z-
dc.date.issued2006en_HK
dc.identifier.citationWorld Journal Of Surgery, 2006, v. 30 n. 4, p. 598-604en_HK
dc.identifier.issn0364-2313en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84343-
dc.description.abstractBackground: This study aimed to evaluate the surgical strategies, operative results, and oncological outcomes of elderly patients who underwent curative resection for mid and distal rectal cancer. Comparison was made with patients of younger age. Study Design: Of the 612 patients who underwent curative resection for rectal cancer, 133 were older than 75 years of age. Comparisons were made between the young and elderly patients in the aspects of operative strategies, operative results, and long-term outcomes. Results: Resection resulting in a permanent end colostomy was performed in 96 patients (15.7%), and there was no difference between young and elderly patients. There was a female predominance in the elderly group. Elderly patients also had a higher incidence of comorbid medical diseases, especially cardiovascular and neurological diseases. The operative time, blood loss, and incidence of intraoperative complications did not differ in the two groups. However, significantly fewer elderly patients underwent adjuvant radiation and/or chemotherapy. The overall 30-day mortality was 1.14%. There was no difference between the elderly patients and younger patients in hospital mortality (P = 0.178). The complication rates of the elderly and young patients were 36.8% and 30.1%, respectively (P = 0.141). Comparison between the individual complications in the elderly and young patients revealed significantly more cardiovascular complications in the elderly patients. With the median follow up of the surviving patients of 45.1 months, the overall 5-year survival of the elderly and younger groups was 47.7% and 70.1%, respectively (P < 0.001). The 5-year cancer-specific survival was 75.4% and 67.5% in the young and elderly patients, respectively (P = 0.061). Conclusions: Curative resection for mid and distal rectal cancer for the elderly can be performed safely with the same strategies of sphincter preservation used for younger patients. The postoperative complications and the 5-year cancer-specific survival rates were similar to those of younger patients. © 2006 by the Société Internationale de Chirurgie.en_HK
dc.languageengen_HK
dc.publisherSpringer New York LLC. The Journal's web site is located at http://link.springer.de/link/service/journals/00268/en_HK
dc.relation.ispartofWorld Journal of Surgeryen_HK
dc.titleOutcomes of surgery for mid and distal rectal cancer in the elderlyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0364-2313&volume=30&issue=4&spage=598&epage=604&date=2006&atitle=Outcomes+of+surgery+for+mid+and+distal+rectal+cancer+in+the+elderly+en_HK
dc.identifier.emailWai, LL: lawwl@hkucc.hku.hken_HK
dc.identifier.authorityWai, LL=rp00436en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00268-005-0442-xen_HK
dc.identifier.pmid16568224-
dc.identifier.scopuseid_2-s2.0-33645561297en_HK
dc.identifier.hkuros116709en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645561297&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume30en_HK
dc.identifier.issue4en_HK
dc.identifier.spage598en_HK
dc.identifier.epage604en_HK
dc.identifier.isiWOS:000236618600018-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWai, LL=7103147867en_HK
dc.identifier.scopusauthoridHok, KC=12801539000en_HK
dc.identifier.scopusauthoridHo, JWC=7402649983en_HK
dc.identifier.scopusauthoridYee, ML=12801775800en_HK
dc.identifier.scopusauthoridChi, LS=12801406100en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats