File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1001/archsurg.137.4.465
- Scopus: eid_2-s2.0-0036080592
- PMID: 11926955
- WOS: WOS:000174841900027
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Choledochal cysts in adults
Title | Choledochal cysts in adults |
---|---|
Authors | |
Issue Date | 2002 |
Publisher | American Medical Association. The Journal's web site is located at http://www.archsurg.com |
Citation | Archives Of Surgery, 2002, v. 137 n. 4, p. 465-468 How to Cite? |
Abstract | Hypothesis: Choledochal cyst is rarely diagnosed in adulthood. When complicated by biliary tract malignancy, the disease has a distinct presentation and carries a dismal prognosis despite radical surgical resection. Design: Retrospective study. Setting: Tertiary referral center. Patients: A retrospective study was performed on 30 adult patients who presented with choledochal cyst from January 1, 1989, to December 31, 2000. Main Outcome Measures: The clinical presentation, management, and outcome of patients with and without biliary tract malignancy. Results: Nine patients (30%) had biliary tract malignancy complicating choledochal cyst (group A). Compared with 21 patients without malignancy (group B), group A patients had a significantly higher incidence of previous internal drainage operations for choledochal cyst (P =.049) and presentation with cholangitis (P =.03). Four patients in group A underwent pancreaticoduodenectomy and 3 received a palliative biliary drainage operation. The overall median survival of patients in group A was 12 months. Complete excision of choledochal cyst and Roux-en-Y hepaticojejunostomy were performed for all patients in group B, among whom 2 underwent concomitant hemihepatectomy. The operative morbidity and mortality were 14% and 0%, respectively, and there were no long-term complications with a median follow-up of 66 months. Conclusions: Biliary tract malignancy complicating choledochal cyst in adults should be suspected in patients with a history of internal drainage of choledochal cyst and presentation with cholangitis. Complete excision of choledochal cyst with Roux-en-Y hepaticojejunostomy is the treatment of choice for patients without malignancy and can be performed with low operative morbidity and absence of long-term complications in adult patients. |
Persistent Identifier | http://hdl.handle.net/10722/84292 |
ISSN | 2014 Impact Factor: 4.926 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, CL | en_HK |
dc.contributor.author | Fan, ST | en_HK |
dc.contributor.author | Lo, CM | en_HK |
dc.contributor.author | Lam, CM | en_HK |
dc.contributor.author | Poon, RTP | en_HK |
dc.contributor.author | Wong, J | en_HK |
dc.date.accessioned | 2010-09-06T08:51:13Z | - |
dc.date.available | 2010-09-06T08:51:13Z | - |
dc.date.issued | 2002 | en_HK |
dc.identifier.citation | Archives Of Surgery, 2002, v. 137 n. 4, p. 465-468 | en_HK |
dc.identifier.issn | 0004-0010 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/84292 | - |
dc.description.abstract | Hypothesis: Choledochal cyst is rarely diagnosed in adulthood. When complicated by biliary tract malignancy, the disease has a distinct presentation and carries a dismal prognosis despite radical surgical resection. Design: Retrospective study. Setting: Tertiary referral center. Patients: A retrospective study was performed on 30 adult patients who presented with choledochal cyst from January 1, 1989, to December 31, 2000. Main Outcome Measures: The clinical presentation, management, and outcome of patients with and without biliary tract malignancy. Results: Nine patients (30%) had biliary tract malignancy complicating choledochal cyst (group A). Compared with 21 patients without malignancy (group B), group A patients had a significantly higher incidence of previous internal drainage operations for choledochal cyst (P =.049) and presentation with cholangitis (P =.03). Four patients in group A underwent pancreaticoduodenectomy and 3 received a palliative biliary drainage operation. The overall median survival of patients in group A was 12 months. Complete excision of choledochal cyst and Roux-en-Y hepaticojejunostomy were performed for all patients in group B, among whom 2 underwent concomitant hemihepatectomy. The operative morbidity and mortality were 14% and 0%, respectively, and there were no long-term complications with a median follow-up of 66 months. Conclusions: Biliary tract malignancy complicating choledochal cyst in adults should be suspected in patients with a history of internal drainage of choledochal cyst and presentation with cholangitis. Complete excision of choledochal cyst with Roux-en-Y hepaticojejunostomy is the treatment of choice for patients without malignancy and can be performed with low operative morbidity and absence of long-term complications in adult patients. | en_HK |
dc.language | eng | en_HK |
dc.publisher | American Medical Association. The Journal's web site is located at http://www.archsurg.com | en_HK |
dc.relation.ispartof | Archives of Surgery | en_HK |
dc.title | Choledochal cysts in adults | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0004-0010&volume=137&spage=465&epage=468&date=2002&atitle=Choledochal+cysts+in+adults | en_HK |
dc.identifier.email | Fan, ST: stfan@hku.hk | en_HK |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | en_HK |
dc.identifier.email | Poon, RTP: poontp@hku.hk | en_HK |
dc.identifier.email | Wong, J: jwong@hkucc.hku.hk | en_HK |
dc.identifier.authority | Fan, ST=rp00355 | en_HK |
dc.identifier.authority | Lo, CM=rp00412 | en_HK |
dc.identifier.authority | Poon, RTP=rp00446 | en_HK |
dc.identifier.authority | Wong, J=rp00322 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1001/archsurg.137.4.465 | - |
dc.identifier.pmid | 11926955 | - |
dc.identifier.scopus | eid_2-s2.0-0036080592 | en_HK |
dc.identifier.hkuros | 68696 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0036080592&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 137 | en_HK |
dc.identifier.issue | 4 | en_HK |
dc.identifier.spage | 465 | en_HK |
dc.identifier.epage | 468 | en_HK |
dc.identifier.isi | WOS:000174841900027 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Liu, CL=7409789712 | en_HK |
dc.identifier.scopusauthorid | Fan, ST=7402678224 | en_HK |
dc.identifier.scopusauthorid | Lo, CM=7401771672 | en_HK |
dc.identifier.scopusauthorid | Lam, CM=36799183200 | en_HK |
dc.identifier.scopusauthorid | Poon, RTP=7103097223 | en_HK |
dc.identifier.scopusauthorid | Wong, J=8049324500 | en_HK |
dc.identifier.issnl | 0004-0010 | - |