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Article: Multi-country study on the prevalence and clinical features of peripheral arterial disease in asian type 2 diabetes patients at high risk of atherosclerosis

TitleMulti-country study on the prevalence and clinical features of peripheral arterial disease in asian type 2 diabetes patients at high risk of atherosclerosis
Authors
KeywordsAsia
Diabetes complications
Diabetes mellitus
Epidemiology
Peripheral vascular diseases
Risk factors
Issue Date2007
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/diabres
Citation
Diabetes Research And Clinical Practice, 2007, v. 76 n. 1, p. 82-92 How to Cite?
AbstractObjective: PAD-SEARCH was the first international study to investigate the prevalence of peripheral arterial disease (PAD) in Asian type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD. Subjects and methods: In total 6625 type 2 diabetic patients aged 50 and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in Korea, China, Taiwan, Hong Kong, Indonesia, Thailand and the Philippines. Results: Mean patient age was 63.7 ± 8.2 years and mean duration of diabetes was 10.3 ± 8.0 years. One thousand one hundred and seventy-two (17.7%) subjects were diagnosed as PAD by ABI (≤0.9). PAD subjects had a significantly longer duration of diabetes, hypertension, higher HbA1c, and a significantly lower mean BMI than non-PAD subjects. In terms of lipid profiles, triglyceride was the only significant variable. Notably, mean ABI and baPWV in females were significantly poorer than age matched males in subjects with a normal ABI. However, mean ABI and baPWV in males were significantly poorer than in age matched females in subjects with PAD. Conclusions: These findings suggest that PAD is a common complication in Asian type 2 diabetic patients. Therefore, PAD screening and treatment should be emphasized for Asian diabetic patients with high risk factors. © 2006 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/84185
ISSN
2015 Impact Factor: 3.045
2015 SCImago Journal Rankings: 1.338
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorRhee, SYen_HK
dc.contributor.authorGuan, Hen_HK
dc.contributor.authorLiu, ZMen_HK
dc.contributor.authorCheng, SWKen_HK
dc.contributor.authorWaspadji, Sen_HK
dc.contributor.authorPalmes, Pen_HK
dc.contributor.authorTai, TYen_HK
dc.contributor.authorSuwanwalaikorn, Sen_HK
dc.contributor.authorKim, YSen_HK
dc.date.accessioned2010-09-06T08:49:58Z-
dc.date.available2010-09-06T08:49:58Z-
dc.date.issued2007en_HK
dc.identifier.citationDiabetes Research And Clinical Practice, 2007, v. 76 n. 1, p. 82-92en_HK
dc.identifier.issn0168-8227en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84185-
dc.description.abstractObjective: PAD-SEARCH was the first international study to investigate the prevalence of peripheral arterial disease (PAD) in Asian type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD. Subjects and methods: In total 6625 type 2 diabetic patients aged 50 and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in Korea, China, Taiwan, Hong Kong, Indonesia, Thailand and the Philippines. Results: Mean patient age was 63.7 ± 8.2 years and mean duration of diabetes was 10.3 ± 8.0 years. One thousand one hundred and seventy-two (17.7%) subjects were diagnosed as PAD by ABI (≤0.9). PAD subjects had a significantly longer duration of diabetes, hypertension, higher HbA1c, and a significantly lower mean BMI than non-PAD subjects. In terms of lipid profiles, triglyceride was the only significant variable. Notably, mean ABI and baPWV in females were significantly poorer than age matched males in subjects with a normal ABI. However, mean ABI and baPWV in males were significantly poorer than in age matched females in subjects with PAD. Conclusions: These findings suggest that PAD is a common complication in Asian type 2 diabetic patients. Therefore, PAD screening and treatment should be emphasized for Asian diabetic patients with high risk factors. © 2006 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/diabresen_HK
dc.relation.ispartofDiabetes Research and Clinical Practiceen_HK
dc.rightsDiabetes Research and Clinical Practice. Copyright © Elsevier Ireland Ltd.en_HK
dc.subjectAsiaen_HK
dc.subjectDiabetes complicationsen_HK
dc.subjectDiabetes mellitusen_HK
dc.subjectEpidemiologyen_HK
dc.subjectPeripheral vascular diseasesen_HK
dc.subjectRisk factorsen_HK
dc.titleMulti-country study on the prevalence and clinical features of peripheral arterial disease in asian type 2 diabetes patients at high risk of atherosclerosisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0168-8227&volume=76&issue=1&spage=82&epage=92&date=2007&atitle=Multi-country+study+on+the+prevalence+and+clinical+features+of+peripheral+arterial+disease+in+Asian+type+2+diabetes+patients+at+high+risk+of+atherosclerosisen_HK
dc.identifier.emailCheng, SWK: wkcheng@hkucc.hku.hken_HK
dc.identifier.authorityCheng, SWK=rp00374en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.diabres.2006.07.029en_HK
dc.identifier.pmid16950543en_HK
dc.identifier.scopuseid_2-s2.0-33846920360en_HK
dc.identifier.hkuros127524en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33846920360&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume76en_HK
dc.identifier.issue1en_HK
dc.identifier.spage82en_HK
dc.identifier.epage92en_HK
dc.identifier.isiWOS:000244991900013-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridRhee, SY=8606892300en_HK
dc.identifier.scopusauthoridGuan, H=7202612886en_HK
dc.identifier.scopusauthoridLiu, ZM=7406671362en_HK
dc.identifier.scopusauthoridCheng, SWK=7404684779en_HK
dc.identifier.scopusauthoridWaspadji, S=8678136400en_HK
dc.identifier.scopusauthoridPalmes, P=15844319900en_HK
dc.identifier.scopusauthoridTai, TY=36004407000en_HK
dc.identifier.scopusauthoridSuwanwalaikorn, S=6506935197en_HK
dc.identifier.scopusauthoridKim, YS=36063850100en_HK

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