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Article: Anomalies associated with oesophageal atresia in Asians and Europeans

TitleAnomalies associated with oesophageal atresia in Asians and Europeans
Authors
Issue Date2002
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00383/index.htm
Citation
Pediatric Surgery International, 2002, v. 18 n. 4, p. 241-243 How to Cite?
AbstractOesophageal Atresia (Oa) Is Often Associated With Anomalies Of Other Systems. The Genetic Contribution To The Formation Of The Vacterl Association Is Not Clear. The Objective Of This Study Was To Evaluate The Incidence Of Associated Anomalies In Two Different Racial Populations. The Associated Anomalies In Neonates With Oa Managed In An Asian And A European Paediatric Surgical Centre From 1982 To 1998 Were Reviewed. Non-Asian And Non-European Patients Were Excluded From The Respective Centres. The Incidence Of Anomalies Was Compared Using Fisher's Exact Test, Taking P Below 0.05 As Statistically Significant. Forty-Eight Consecutive Asian (25 Boys And 23 Girls) And 34 Consecutive European Patients (20 Boys And 14 Girls) Were Included In The Analysis. The Percentage Of Patients With At Least One Associated Anomaly Was 50% And 74% In The Asian And European Populations, Respectively, Which Was Significantly Different (P = 0.04). There Was No Statistically Significant Difference In The Incidence Of Associated Cardiovascular (29% Vs 39%), Anorectal (11% Vs. 18%), And Musculoskeletal (16% Vs 22%) Anomalies, Duodenal Atresia (4% Vs 3%), Or Down's Syndrome (3% Vs 6%) Between The Two Populations. However, The European Patients Had A Significantly Higher Incidence Of Urogenital (Ug) Anomalies (26% Vs 4%, P = 0.006), The Most Common Being Agenesis (N = 4) And Dysplasia (N = 3) Of One Or Both Kidneys. Hereditary Factors May Influence The Incidence Of Associated Anomalies In Children With Oa, Particularly Of The Ug System. However, Environmental Factors Cannot Be Excluded.
Persistent Identifierhttp://hdl.handle.net/10722/84138
ISSN
2015 Impact Factor: 1.01
2015 SCImago Journal Rankings: 0.409
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorvan Heurn, LWEen_HK
dc.contributor.authorCheng, Wen_HK
dc.contributor.authorde Vries, Ben_HK
dc.contributor.authorSaing, Hen_HK
dc.contributor.authorJansen, NJGen_HK
dc.contributor.authorKootstra, Gen_HK
dc.contributor.authorTam, PKHen_HK
dc.date.accessioned2010-09-06T08:49:24Z-
dc.date.available2010-09-06T08:49:24Z-
dc.date.issued2002en_HK
dc.identifier.citationPediatric Surgery International, 2002, v. 18 n. 4, p. 241-243en_US
dc.identifier.issn0179-0358en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84138-
dc.description.abstractOesophageal Atresia (Oa) Is Often Associated With Anomalies Of Other Systems. The Genetic Contribution To The Formation Of The Vacterl Association Is Not Clear. The Objective Of This Study Was To Evaluate The Incidence Of Associated Anomalies In Two Different Racial Populations. The Associated Anomalies In Neonates With Oa Managed In An Asian And A European Paediatric Surgical Centre From 1982 To 1998 Were Reviewed. Non-Asian And Non-European Patients Were Excluded From The Respective Centres. The Incidence Of Anomalies Was Compared Using Fisher's Exact Test, Taking P Below 0.05 As Statistically Significant. Forty-Eight Consecutive Asian (25 Boys And 23 Girls) And 34 Consecutive European Patients (20 Boys And 14 Girls) Were Included In The Analysis. The Percentage Of Patients With At Least One Associated Anomaly Was 50% And 74% In The Asian And European Populations, Respectively, Which Was Significantly Different (P = 0.04). There Was No Statistically Significant Difference In The Incidence Of Associated Cardiovascular (29% Vs 39%), Anorectal (11% Vs. 18%), And Musculoskeletal (16% Vs 22%) Anomalies, Duodenal Atresia (4% Vs 3%), Or Down's Syndrome (3% Vs 6%) Between The Two Populations. However, The European Patients Had A Significantly Higher Incidence Of Urogenital (Ug) Anomalies (26% Vs 4%, P = 0.006), The Most Common Being Agenesis (N = 4) And Dysplasia (N = 3) Of One Or Both Kidneys. Hereditary Factors May Influence The Incidence Of Associated Anomalies In Children With Oa, Particularly Of The Ug System. However, Environmental Factors Cannot Be Excluded.en_US
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00383/index.htmen_HK
dc.relation.ispartofPediatric Surgery Internationalen_HK
dc.titleAnomalies associated with oesophageal atresia in Asians and Europeansen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0179-0358&volume=18&spage=241&epage=243&date=2002&atitle=Anomalies+associated+with+oesophageal+atresia+in+Asians+and+Europeansen_HK
dc.identifier.emailSaing, H: saing@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s003830100692en_US
dc.identifier.pmid12021970-
dc.identifier.scopuseid_2-s2.0-0036589663en_US
dc.identifier.hkuros68983en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036589663&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume18en_US
dc.identifier.issue4en_US
dc.identifier.spage241en_US
dc.identifier.epage243en_US
dc.identifier.isiWOS:000176221700006-

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