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Article: Results of surgical salvage for radiation failures of laryngeal carcinoma

TitleResults of surgical salvage for radiation failures of laryngeal carcinoma
Authors
Issue Date1995
PublisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ohns
Citation
Otolaryngology - Head And Neck Surgery, 1995, v. 112 n. 3, p. 405-409 How to Cite?
AbstractThe results of surgical salvage of radiation failures of laryngeal carcinoma were reviewed. There were 167 stage T3 and T4 patients. The operative mortality was 7%. The complication rates were 8% wound infection, 13% chest complication, and 25% anastomotic leakage. After the first salvage operation, pharyngeal recurrence developed in 28 (18%) patients. Seven (25%) patients were feasible for second salvage operation, and none of them had further local recurrence. There were 9 (5%) tracheostomal recurrences. Of the 126 N0 patients, 23 (18%) had nodal recurrence, and only 5 of the nodal recurrences were feasible for salvage by radical neck dissection. All 41 node-positive patients underwent radical neck dissection, and 9 (23%) had nodal recurrence. Of the 126 node-negative patients, 19 (15%) had distant metastasis. Of the 41 node-positive patients, 18 (44%) had distant metastasis. The node-positive patients had a significantly high distant failure rate despite locoregional control of tumor. The adjusted 5-year survival rate of T3-4N0M0 was 45%, and that of T3-4N + M0 was 22%.
Persistent Identifierhttp://hdl.handle.net/10722/84036
ISSN
2015 Impact Factor: 2.021
2015 SCImago Journal Rankings: 1.176
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYuen, APWen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorHo, CMen_HK
dc.date.accessioned2010-09-06T08:48:10Z-
dc.date.available2010-09-06T08:48:10Z-
dc.date.issued1995en_HK
dc.identifier.citationOtolaryngology - Head And Neck Surgery, 1995, v. 112 n. 3, p. 405-409en_HK
dc.identifier.issn0194-5998en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84036-
dc.description.abstractThe results of surgical salvage of radiation failures of laryngeal carcinoma were reviewed. There were 167 stage T3 and T4 patients. The operative mortality was 7%. The complication rates were 8% wound infection, 13% chest complication, and 25% anastomotic leakage. After the first salvage operation, pharyngeal recurrence developed in 28 (18%) patients. Seven (25%) patients were feasible for second salvage operation, and none of them had further local recurrence. There were 9 (5%) tracheostomal recurrences. Of the 126 N0 patients, 23 (18%) had nodal recurrence, and only 5 of the nodal recurrences were feasible for salvage by radical neck dissection. All 41 node-positive patients underwent radical neck dissection, and 9 (23%) had nodal recurrence. Of the 126 node-negative patients, 19 (15%) had distant metastasis. Of the 41 node-positive patients, 18 (44%) had distant metastasis. The node-positive patients had a significantly high distant failure rate despite locoregional control of tumor. The adjusted 5-year survival rate of T3-4N0M0 was 45%, and that of T3-4N + M0 was 22%.en_HK
dc.languageengen_HK
dc.publisherMosby, Inc. The Journal's web site is located at http://www.elsevier.com/locate/ohnsen_HK
dc.relation.ispartofOtolaryngology - Head and Neck Surgeryen_HK
dc.rightsOtolaryngology - Head and Neck Surgery. Copyright © Mosby, Inc.en_HK
dc.titleResults of surgical salvage for radiation failures of laryngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0194-5998&volume=112&spage=405&epage=409&date=1995&atitle=Results+of+surgical+salvage+for+radiation+failures+of+laryngeal+carcinomaen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0194-5998(95)70274-1en_HK
dc.identifier.pmid7870440-
dc.identifier.scopuseid_2-s2.0-0028943694en_HK
dc.identifier.hkuros3780en_HK
dc.identifier.hkuros3690-
dc.identifier.volume112en_HK
dc.identifier.issue3en_HK
dc.identifier.spage405en_HK
dc.identifier.epage409en_HK
dc.identifier.isiWOS:A1995QK71500007-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYuen, APW=7006290111en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridHo, CM=7404652540en_HK

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