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Article: Complications of resection of malignant tumours of the skull base: Outcome and solution

TitleComplications of resection of malignant tumours of the skull base: Outcome and solution
Authors
KeywordsComplications
Skull base
Surgery
Tumours
Issue Date2007
PublisherSpringer Verlag.
Citation
European Archives Of Oto-Rhino-Laryngology, 2007, v. 264 n. 7, p. 733-739 How to Cite?
AbstractThe results of surgical resection of malignant tumours located at the skull base have improved significantly over the years. There are however still some complications associated with these procedures. For central skull base lesions, the anterolateral approach exposes the region adequately for an oncological resection to be carried out. The development of palatal fistula in irradiated patient has been a nuisance. With modification of the palatal incision, this problem is now eliminated. For the management of osteoradronecrosis of the skull base, an uncommon late complication, a microvascular free muscle flap is required. For malignant pathologies located at the anterior skull base, a combined craniofacial resection is the treatment of choice. Our experience as well as those reported in the literature showed that when the skull base defect was small, the pericranial and the galeofrontalis flap were adequate for reconstruction. For larger defects, a microvascular free flap would be used. When the internal carotid artery is included in the resection, an extracranial-intracranial arterial bypass should be created before the resection of tumour. The most serious complication is the development of cerebral spinal fluid leakage. Conservative treatment is applicable for small leakage while for large leakage; the exact location of the leak must be identified before the defect can be closed successfully. © 2007 Springer-Verlag.
Persistent Identifierhttp://hdl.handle.net/10722/84009
ISSN
2015 Impact Factor: 1.627
2015 SCImago Journal Rankings: 0.755
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_HK
dc.contributor.authorNg, RWMen_HK
dc.date.accessioned2010-09-06T08:47:50Z-
dc.date.available2010-09-06T08:47:50Z-
dc.date.issued2007en_HK
dc.identifier.citationEuropean Archives Of Oto-Rhino-Laryngology, 2007, v. 264 n. 7, p. 733-739en_HK
dc.identifier.issn0937-4477en_HK
dc.identifier.urihttp://hdl.handle.net/10722/84009-
dc.description.abstractThe results of surgical resection of malignant tumours located at the skull base have improved significantly over the years. There are however still some complications associated with these procedures. For central skull base lesions, the anterolateral approach exposes the region adequately for an oncological resection to be carried out. The development of palatal fistula in irradiated patient has been a nuisance. With modification of the palatal incision, this problem is now eliminated. For the management of osteoradronecrosis of the skull base, an uncommon late complication, a microvascular free muscle flap is required. For malignant pathologies located at the anterior skull base, a combined craniofacial resection is the treatment of choice. Our experience as well as those reported in the literature showed that when the skull base defect was small, the pericranial and the galeofrontalis flap were adequate for reconstruction. For larger defects, a microvascular free flap would be used. When the internal carotid artery is included in the resection, an extracranial-intracranial arterial bypass should be created before the resection of tumour. The most serious complication is the development of cerebral spinal fluid leakage. Conservative treatment is applicable for small leakage while for large leakage; the exact location of the leak must be identified before the defect can be closed successfully. © 2007 Springer-Verlag.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag.en_HK
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngologyen_HK
dc.subjectComplicationsen_HK
dc.subjectSkull baseen_HK
dc.subjectSurgeryen_HK
dc.subjectTumoursen_HK
dc.subject.meshHumans-
dc.subject.meshOtorhinolaryngologic Surgical Procedures - adverse effects-
dc.subject.meshPostoperative Complications-
dc.subject.meshSkull Base Neoplasms - surgery-
dc.titleComplications of resection of malignant tumours of the skull base: Outcome and solutionen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0937-4477&volume=264&spage=733&epage=739&date=2007&atitle=Complications+of+resection+of+malignant+tumours+of+the+skull+base:+outcome+and+solutionen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00405-007-0266-4en_HK
dc.identifier.pmid17333231-
dc.identifier.scopuseid_2-s2.0-34249294555en_HK
dc.identifier.hkuros137516en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34249294555&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume264en_HK
dc.identifier.issue7en_HK
dc.identifier.spage733en_HK
dc.identifier.epage739en_HK
dc.identifier.isiWOS:000246766900004-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridNg, RWM=7102153861en_HK
dc.identifier.citeulike1529608-

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