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Article: Factors affecting outcomes of prenatally-diagnosed tumours

TitleFactors affecting outcomes of prenatally-diagnosed tumours
Authors
KeywordsPrenatally-diagnosed tumours
Site
Vascularity
Issue Date2002
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
Citation
Prenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443 How to Cite?
AbstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/83780
ISSN
2014 Impact Factor: 3.268
2014 SCImago Journal Rankings: 1.542
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, KLen_HK
dc.contributor.authorTang, MHYen_HK
dc.contributor.authorTse, HYen_HK
dc.contributor.authorTang, RYKen_HK
dc.contributor.authorLam, HSWen_HK
dc.contributor.authorLee, CPen_HK
dc.contributor.authorTam, PKHen_HK
dc.date.accessioned2010-09-06T08:45:07Z-
dc.date.available2010-09-06T08:45:07Z-
dc.date.issued2002en_HK
dc.identifier.citationPrenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443en_HK
dc.identifier.issn0197-3851en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83780-
dc.description.abstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252en_HK
dc.relation.ispartofPrenatal Diagnosisen_HK
dc.rightsPrenatal Diagnosis. Copyright © John Wiley & Sons Ltd.en_HK
dc.subjectPrenatally-diagnosed tumoursen_HK
dc.subjectSiteen_HK
dc.subjectVascularityen_HK
dc.titleFactors affecting outcomes of prenatally-diagnosed tumoursen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0197-3851&volume=22&spage=437&epage=443&date=2002&atitle=Factors+affecting+outcomes+of+prenatally-diagnosed+tumoursen_HK
dc.identifier.emailTang, MHY: mhytang@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hku.hken_HK
dc.identifier.authorityTang, MHY=rp01701en_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1002/pd.324en_HK
dc.identifier.pmid12001204en_HK
dc.identifier.scopuseid_2-s2.0-0036114384en_HK
dc.identifier.hkuros69027en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036114384&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue5en_HK
dc.identifier.spage437en_HK
dc.identifier.epage443en_HK
dc.identifier.isiWOS:000175737500022-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChan, KL=37004089600en_HK
dc.identifier.scopusauthoridTang, MHY=8943401300en_HK
dc.identifier.scopusauthoridTse, HY=36772585300en_HK
dc.identifier.scopusauthoridTang, RYK=7202300287en_HK
dc.identifier.scopusauthoridLam, HSW=16022602300en_HK
dc.identifier.scopusauthoridLee, CP=7410149538en_HK
dc.identifier.scopusauthoridTam, PKH=7202539421en_HK

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