Article: Factors affecting outcomes of prenatally-diagnosed tumours

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TitleFactors affecting outcomes of prenatally-diagnosed tumours
AuthorsChan, KL2 5
Tang, MHY5
Tse, HY1 4
Tang, RYK3 5
Lam, HSW4 5
Lee, CP5
Tam, PKH5
KeywordsPrenatally-diagnosed tumours
Site
Vascularity
Issue Date2002
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
CitationPrenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443 [How to Cite?]
DOI: http://dx.doi.org/10.1002/pd.324
AbstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.
ISSN0197-3851
2011 Impact Factor: 2.106
2011 SCImago Journal Rankings: 0.150
DOIhttp://dx.doi.org/10.1002/pd.324
ISI Accession Number IDWOS:000175737500022
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorChan, KL
dc.contributor.authorTang, MHY
dc.contributor.authorTse, HY
dc.contributor.authorTang, RYK
dc.contributor.authorLam, HSW
dc.contributor.authorLee, CP
dc.contributor.authorTam, PKH
dc.date.accessioned2010-09-06T08:45:07Z
dc.date.available2010-09-06T08:45:07Z
dc.date.issued2002
dc.description.abstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.
dc.description.naturelink_to_subscribed_fulltext
dc.identifier.citationPrenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443 [How to Cite?]
DOI: http://dx.doi.org/10.1002/pd.324
dc.identifier.doihttp://dx.doi.org/10.1002/pd.324
dc.identifier.epage443
dc.identifier.hkuros69027
dc.identifier.isiWOS:000175737500022
dc.identifier.issn0197-3851
2011 Impact Factor: 2.106
2011 SCImago Journal Rankings: 0.150
dc.identifier.issue5
dc.identifier.openurl
dc.identifier.pmid12001204
dc.identifier.scopuseid_2-s2.0-0036114384
dc.identifier.spage437
dc.identifier.urihttp://hdl.handle.net/10722/83780
dc.identifier.volume22
dc.languageeng
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
dc.publisher.placeUnited Kingdom
dc.relation.ispartofPrenatal Diagnosis
dc.relation.referencesReferences in Scopus
dc.rightsPrenatal Diagnosis. Copyright © John Wiley & Sons Ltd.
dc.subjectPrenatally-diagnosed tumours
dc.subjectSite
dc.subjectVascularity
dc.titleFactors affecting outcomes of prenatally-diagnosed tumours
dc.typeArticle
Author Affiliations
  1. Kwong Wah Hospital
  2. The University of Hong Kong
  3. Pamela Youde Nethersole Eastern Hospital
  4. Tsan Yuk Hospital
  5. Queen Mary Hospital Hong Kong