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Article: Factors affecting outcomes of prenatally-diagnosed tumours
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TitleFactors affecting outcomes of prenatally-diagnosed tumours
 
AuthorsChan, KL5 2
Tang, MHY5
Tse, HY1 4
Tang, RYK5 3
Lam, HSW5 4
Lee, CP5
Tam, PKH5
 
KeywordsPrenatally-diagnosed tumours
Site
Vascularity
 
Issue Date2002
 
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
 
CitationPrenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443 [How to Cite?]
DOI: http://dx.doi.org/10.1002/pd.324
 
AbstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.
 
ISSN0197-3851
2013 Impact Factor: 2.514
 
DOIhttp://dx.doi.org/10.1002/pd.324
 
ISI Accession Number IDWOS:000175737500022
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorChan, KL
 
dc.contributor.authorTang, MHY
 
dc.contributor.authorTse, HY
 
dc.contributor.authorTang, RYK
 
dc.contributor.authorLam, HSW
 
dc.contributor.authorLee, CP
 
dc.contributor.authorTam, PKH
 
dc.date.accessioned2010-09-06T08:45:07Z
 
dc.date.available2010-09-06T08:45:07Z
 
dc.date.issued2002
 
dc.description.abstractObjective: The outcomes of prenatally-diagnosed tumours affect obstetrical management and parental decisions. The present study reviews the factors affecting outcomes for fetuses with prenatally-diagnosed tumours. Methods: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death. Results: From January 1994 to May 2001, there were 15 fetuses with antenatally-diagnosed tumours: mesoblastic nephroma (MN) (n = 2); neuroblastoma (NB) (n = 2); cystic hygroma (CH) (n = 3); intracranial germ cell tumour (IGCT) (n = 2); sacrococcygeal teratoma (SCT) (n = 3) and haemangioma (liver, n = 2; limb, n = 1). One mother had termination of pregnancy for her fetal SCT. Three mothers had Caesarean section for large fetal heads (CH, n = 2; IGCT, n = 1). Three fetuses died; two with IGCT and one with SCT, who died of heart failure. Two newborns with CH needed emergency intubation and, later, one of them had tracheostomy. One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy. All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy. Conclusion: Prenatally-diagnosed tumours without any other associated abnormality cause morbidity and mortality because of their location and vascularity. Solid tumours are relatively benign. Copyright © 2002 John Wiley & Sons, Ltd.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationPrenatal Diagnosis, 2002, v. 22 n. 5, p. 437-443 [How to Cite?]
DOI: http://dx.doi.org/10.1002/pd.324
 
dc.identifier.doihttp://dx.doi.org/10.1002/pd.324
 
dc.identifier.epage443
 
dc.identifier.hkuros69027
 
dc.identifier.isiWOS:000175737500022
 
dc.identifier.issn0197-3851
2013 Impact Factor: 2.514
 
dc.identifier.issue5
 
dc.identifier.openurl
 
dc.identifier.pmid12001204
 
dc.identifier.scopuseid_2-s2.0-0036114384
 
dc.identifier.spage437
 
dc.identifier.urihttp://hdl.handle.net/10722/83780
 
dc.identifier.volume22
 
dc.languageeng
 
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/2252
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofPrenatal Diagnosis
 
dc.relation.referencesReferences in Scopus
 
dc.rightsPrenatal Diagnosis. Copyright © John Wiley & Sons Ltd.
 
dc.subjectPrenatally-diagnosed tumours
 
dc.subjectSite
 
dc.subjectVascularity
 
dc.titleFactors affecting outcomes of prenatally-diagnosed tumours
 
dc.typeArticle
 
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<contributor.author>Lam, HSW</contributor.author>
<contributor.author>Lee, CP</contributor.author>
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Author Affiliations
  1. Kwong Wah Hospital
  2. The University of Hong Kong
  3. Pamela Youde Nethersole Eastern Hospital
  4. Tsan Yuk Hospital
  5. Queen Mary Hospital Hong Kong