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Article: Quality of life of patients with recurrent nasopharyngeal carcinoma treated with nasopharyngectomy using the maxillary swing approach

TitleQuality of life of patients with recurrent nasopharyngeal carcinoma treated with nasopharyngectomy using the maxillary swing approach
Authors
Issue Date2006
PublisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.com
Citation
Archives Of Otolaryngology - Head And Neck Surgery, 2006, v. 132 n. 3, p. 309-316 How to Cite?
AbstractObjective: To investigate factors affecting the quality of life (QOL) of patients with recurrent nasopharyngeal carcinoma who underwent a nasopharyngectomy using the maxillary swing approach. Design: Cross-sectional study using self-administered questionnaire data and medical chart review. Setting: Tertiary cancer referral center. Patients: Patients with recurrent nasopharyngeal carcinoma who underwent a nasopharyngectomy using the maxillary swing approach between January 1998 and December 2003, had a minimal follow-up of 3 months, and completed the questionnaire. Interventions: We measured QOL using the validated traditional Chinese version of the European Organization for Research and Treatment of Cancer core questionnaire and head and neck module. Main Outcome Measures: Descriptive analysis of the results and comparison of scores for each QOL domain, stratified by presence of postoperative trismus, presence of postoperative palatal fistula, sex, age (≤45 years and >45 years), duration of treatment (≤1 year and >1 year), and disease status at follow-up, were performed using nonparametric tests. Results: Of the 50 eligible patients, 41 (32 men and 9 women; mean [SD] age, 51.5 [10.4] years) participated in the study. The mean±SD global QOL scale score of the participants was 68.7±24.2. Social functioning score was the lowest (64.6±25.9) of the 5 functioning scales. Fatigue and financial difficulties were the most common general concerns. Dryness of mouth, sticky saliva, and limited mouth opening were the most common head and neck problems. Women were found to have significantly lower QOL scores in the fatigue (P=.03), diarrhea (P=.03), and emotional functioning (P=.05) domains than men. The presence of severe trismus after the maxillary swing approach was significantly associated with a low QOL score in the mouth opening (P=.001), sticky saliva (P=.006), mouth dryness (P=.02), and social eating (P=.05) domains. However, the presence of palatal fistula, age, duration of treatment, and disease status at follow-up did not result in any significant differences on the QOL scores. Conclusions: The QOL of patients treated with nasopharyngectomy using the maxillary swing approach to treat recurrent nasopharyngeal carcinoma was good. Female sex and the presence of postoperative trismus were factors significantly related to some of the QOL domain differences after surgery. ©2006 American Medical Association. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/83772
ISSN
2014 Impact Factor: 2.327
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNg, RWMen_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2010-09-06T08:45:02Z-
dc.date.available2010-09-06T08:45:02Z-
dc.date.issued2006en_HK
dc.identifier.citationArchives Of Otolaryngology - Head And Neck Surgery, 2006, v. 132 n. 3, p. 309-316en_HK
dc.identifier.issn0886-4470en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83772-
dc.description.abstractObjective: To investigate factors affecting the quality of life (QOL) of patients with recurrent nasopharyngeal carcinoma who underwent a nasopharyngectomy using the maxillary swing approach. Design: Cross-sectional study using self-administered questionnaire data and medical chart review. Setting: Tertiary cancer referral center. Patients: Patients with recurrent nasopharyngeal carcinoma who underwent a nasopharyngectomy using the maxillary swing approach between January 1998 and December 2003, had a minimal follow-up of 3 months, and completed the questionnaire. Interventions: We measured QOL using the validated traditional Chinese version of the European Organization for Research and Treatment of Cancer core questionnaire and head and neck module. Main Outcome Measures: Descriptive analysis of the results and comparison of scores for each QOL domain, stratified by presence of postoperative trismus, presence of postoperative palatal fistula, sex, age (≤45 years and >45 years), duration of treatment (≤1 year and >1 year), and disease status at follow-up, were performed using nonparametric tests. Results: Of the 50 eligible patients, 41 (32 men and 9 women; mean [SD] age, 51.5 [10.4] years) participated in the study. The mean±SD global QOL scale score of the participants was 68.7±24.2. Social functioning score was the lowest (64.6±25.9) of the 5 functioning scales. Fatigue and financial difficulties were the most common general concerns. Dryness of mouth, sticky saliva, and limited mouth opening were the most common head and neck problems. Women were found to have significantly lower QOL scores in the fatigue (P=.03), diarrhea (P=.03), and emotional functioning (P=.05) domains than men. The presence of severe trismus after the maxillary swing approach was significantly associated with a low QOL score in the mouth opening (P=.001), sticky saliva (P=.006), mouth dryness (P=.02), and social eating (P=.05) domains. However, the presence of palatal fistula, age, duration of treatment, and disease status at follow-up did not result in any significant differences on the QOL scores. Conclusions: The QOL of patients treated with nasopharyngectomy using the maxillary swing approach to treat recurrent nasopharyngeal carcinoma was good. Female sex and the presence of postoperative trismus were factors significantly related to some of the QOL domain differences after surgery. ©2006 American Medical Association. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.comen_HK
dc.relation.ispartofArchives of Otolaryngology - Head and Neck Surgeryen_HK
dc.titleQuality of life of patients with recurrent nasopharyngeal carcinoma treated with nasopharyngectomy using the maxillary swing approachen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0886-4470&volume=132&spage=309&epage=316&date=2006&atitle=Quality+of+life+of+patients+with+recurrent+nasopharyngeal+carcinoma+treated+with+nasopharyngectomy+using+the+maxillary+swing+approachen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1001/archotol.132.3.309en_HK
dc.identifier.pmid16549752-
dc.identifier.scopuseid_2-s2.0-33645221637en_HK
dc.identifier.hkuros126140en_HK
dc.identifier.hkuros137510-
dc.identifier.hkuros116847-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33645221637&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume132en_HK
dc.identifier.issue3en_HK
dc.identifier.spage309en_HK
dc.identifier.epage316en_HK
dc.identifier.isiWOS:000236120100010-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridNg, RWM=7102153861en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.issnl0886-4470-

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