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Article: Validation of POSSUM scoring systems for audit of major hepatectomy

TitleValidation of POSSUM scoring systems for audit of major hepatectomy
Authors
Issue Date2004
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uk
Citation
British Journal Of Surgery, 2004, v. 91 n. 4, p. 450-454 How to Cite?
AbstractBackground: The aim of the study was to validate the use of Physiological and Operative Severity Score in the enumeration of Mortality and morbidity (POSSUM) and Portsmouth (P) POSSUM scoring systems to predict postoperative mortality in a group of Chinese patients who had a major hepatectomy for hepatocellular carcinoma. Methods: A retrospective analysis was performed on data collected prospectively over a 6-year interval from January 1997 to December 2002. The mortality risks were calculated using both the POSSUM and the P-POSSUM equations. Results: Two hundred and fifty-nine patients underwent major hepatectomy; there were 17 (6-6 per cent) postoperative deaths. Of 32 preoperative and intraoperative variables studied, age, smoking habit, serum creatinine concentration, American Society of Anesthesiologists grade, and physiological and operative severity scores were found to be significant factors predicting mortality. On multivariate analysis only the physiological and operative severity scores were independent variables. The POSSUM system overpredicred mortality risk (14-2 per cent) and there was a significant lack of fit in these patients (X2 = 14.1, 3 d.f., P = 0.003). The mortality rate predicted by P-POSSUM was 4.2 per cent and showed no significant lack of fit (x2 = 7.6, 3 d.f., P = 0.055), indicating that it predicted outcome effectively. A new logistic equation was derived from the present patient data set that requires testing prospectively. Conclusion: P-POSSUM significantly predicted outcome in Chinese patients who had major hepatectomy for hepatocellular carcinoma. A modified disease-specific equation requires further testing.
Persistent Identifierhttp://hdl.handle.net/10722/83751
ISSN
2015 Impact Factor: 5.596
2015 SCImago Journal Rankings: 2.966
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLam, CMen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorYuen, AWCen_HK
dc.contributor.authorLaw, WLen_HK
dc.contributor.authorPoon, Ken_HK
dc.date.accessioned2010-09-06T08:44:46Z-
dc.date.available2010-09-06T08:44:46Z-
dc.date.issued2004en_HK
dc.identifier.citationBritish Journal Of Surgery, 2004, v. 91 n. 4, p. 450-454en_HK
dc.identifier.issn0007-1323en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83751-
dc.description.abstractBackground: The aim of the study was to validate the use of Physiological and Operative Severity Score in the enumeration of Mortality and morbidity (POSSUM) and Portsmouth (P) POSSUM scoring systems to predict postoperative mortality in a group of Chinese patients who had a major hepatectomy for hepatocellular carcinoma. Methods: A retrospective analysis was performed on data collected prospectively over a 6-year interval from January 1997 to December 2002. The mortality risks were calculated using both the POSSUM and the P-POSSUM equations. Results: Two hundred and fifty-nine patients underwent major hepatectomy; there were 17 (6-6 per cent) postoperative deaths. Of 32 preoperative and intraoperative variables studied, age, smoking habit, serum creatinine concentration, American Society of Anesthesiologists grade, and physiological and operative severity scores were found to be significant factors predicting mortality. On multivariate analysis only the physiological and operative severity scores were independent variables. The POSSUM system overpredicred mortality risk (14-2 per cent) and there was a significant lack of fit in these patients (X2 = 14.1, 3 d.f., P = 0.003). The mortality rate predicted by P-POSSUM was 4.2 per cent and showed no significant lack of fit (x2 = 7.6, 3 d.f., P = 0.055), indicating that it predicted outcome effectively. A new logistic equation was derived from the present patient data set that requires testing prospectively. Conclusion: P-POSSUM significantly predicted outcome in Chinese patients who had major hepatectomy for hepatocellular carcinoma. A modified disease-specific equation requires further testing.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.bjs.co.uken_HK
dc.relation.ispartofBritish Journal of Surgeryen_HK
dc.rightsBritish Journal of Surgery. Copyright © John Wiley & Sons Ltd.en_HK
dc.titleValidation of POSSUM scoring systems for audit of major hepatectomyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1323&volume=91&issue=4&spage=450&epage=454&date=2004&atitle=Validation+of+POSSUM+scoring+systems+for+audit+of+major+hepatectomyen_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.emailLaw, WL: lawwl@hkucc.hku.hken_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.identifier.authorityLaw, WL=rp00436en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/bjs.4515en_HK
dc.identifier.pmid15048745-
dc.identifier.scopuseid_2-s2.0-1842867056en_HK
dc.identifier.hkuros90440en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1842867056&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume91en_HK
dc.identifier.issue4en_HK
dc.identifier.spage450en_HK
dc.identifier.epage454en_HK
dc.identifier.isiWOS:000220814700011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLam, CM=7402989820en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridYuen, AWC=9338151700en_HK
dc.identifier.scopusauthoridLaw, WL=7103147867en_HK
dc.identifier.scopusauthoridPoon, K=7006268764en_HK

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