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Article: Outcome analysis of patients with craniofacial resection: Hong Kong experience

TitleOutcome analysis of patients with craniofacial resection: Hong Kong experience
Authors
KeywordsCraniofacial resection
Outcome
Skull base
Issue Date2006
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANS
Citation
Anz Journal Of Surgery, 2006, v. 76 n. 5, p. 313-317 How to Cite?
AbstractBackground: The aim of this study was to evaluate the clinical outcome of patients who underwent craniofacial resection for tumour in the anterior skull base at the University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong between January 1993 and June 2003. Methods: A retrospective review was conducted. The duration of follow up ranged from 1.7 to 119 months (median, 41.8 months). The setting was a tertiary referral centre. Thirty-nine patients, 23 males and 16 females, aged 8-79 years were included. Thirty-four patients had malignant tumour and five patients had benign pathology. The tumour pathology was diversified. Nineteen patients had no treatment before the surgery, and the remaining 20 patients had received surgery, radiotherapy or combined treatment before resection. Patients were given postoperative irradiation and/or chemotherapy depending on the pathology of the tumour and the extent of the disease and clearance at the time of surgery. Results: There was no operative mortality. Complications occurred in 10 patients and among them, three required reoperation. The other complications were managed successfully with conservative measures. The 5-year actuarial disease-free survival for patients with benign and malignant pathology was 100 and 77.6%, respectively. For patients with malignant pathology, 5-year actuarial disease-free survival was 90% when the resection margin was negative at surgery. However, the survival dropped to 53.6% when the resection margin was involved macroscopically. Conclusion: Craniofacial resection was an appropriate surgical approach with acceptable morbidity in selected patients with tumour located at the anterior skull base. Complete excision of malignant tumour could achieve 90% 5-year disease-free actuarial survival. © 2006 Royal Australasian College of Surgeons.
Persistent Identifierhttp://hdl.handle.net/10722/83730
ISSN
2023 Impact Factor: 1.5
2023 SCImago Journal Rankings: 0.453
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, LYen_HK
dc.contributor.authorLam, LKen_HK
dc.contributor.authorFan, YWen_HK
dc.contributor.authorYuen, APWen_HK
dc.contributor.authorWei, WIen_HK
dc.date.accessioned2010-09-06T08:44:32Z-
dc.date.available2010-09-06T08:44:32Z-
dc.date.issued2006en_HK
dc.identifier.citationAnz Journal Of Surgery, 2006, v. 76 n. 5, p. 313-317en_HK
dc.identifier.issn1445-1433en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83730-
dc.description.abstractBackground: The aim of this study was to evaluate the clinical outcome of patients who underwent craniofacial resection for tumour in the anterior skull base at the University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong between January 1993 and June 2003. Methods: A retrospective review was conducted. The duration of follow up ranged from 1.7 to 119 months (median, 41.8 months). The setting was a tertiary referral centre. Thirty-nine patients, 23 males and 16 females, aged 8-79 years were included. Thirty-four patients had malignant tumour and five patients had benign pathology. The tumour pathology was diversified. Nineteen patients had no treatment before the surgery, and the remaining 20 patients had received surgery, radiotherapy or combined treatment before resection. Patients were given postoperative irradiation and/or chemotherapy depending on the pathology of the tumour and the extent of the disease and clearance at the time of surgery. Results: There was no operative mortality. Complications occurred in 10 patients and among them, three required reoperation. The other complications were managed successfully with conservative measures. The 5-year actuarial disease-free survival for patients with benign and malignant pathology was 100 and 77.6%, respectively. For patients with malignant pathology, 5-year actuarial disease-free survival was 90% when the resection margin was negative at surgery. However, the survival dropped to 53.6% when the resection margin was involved macroscopically. Conclusion: Craniofacial resection was an appropriate surgical approach with acceptable morbidity in selected patients with tumour located at the anterior skull base. Complete excision of malignant tumour could achieve 90% 5-year disease-free actuarial survival. © 2006 Royal Australasian College of Surgeons.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/ANSen_HK
dc.relation.ispartofANZ Journal of Surgeryen_HK
dc.subjectCraniofacial resectionen_HK
dc.subjectOutcomeen_HK
dc.subjectSkull baseen_HK
dc.titleOutcome analysis of patients with craniofacial resection: Hong Kong experienceen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0004-8682&volume=76&spage=313&epage=317&date=2005&atitle=Outcome+Analysis+of+Patients+with+Craniofacial+Resection:+Hong+Kong+Experienceen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1445-2197.2006.03713.xen_HK
dc.identifier.pmid16768689-
dc.identifier.scopuseid_2-s2.0-33744723836en_HK
dc.identifier.hkuros116295en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33744723836&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume76en_HK
dc.identifier.issue5en_HK
dc.identifier.spage313en_HK
dc.identifier.epage317en_HK
dc.identifier.isiWOS:000237738500011-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridWong, LY=7402091715en_HK
dc.identifier.scopusauthoridLam, LK=7201984637en_HK
dc.identifier.scopusauthoridFan, YW=7403492523en_HK
dc.identifier.scopusauthoridYuen, APW=7006290111en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.citeulike658612-
dc.identifier.issnl1445-1433-

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