File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Natural history of patients with recurrent chronic hepatitis C virus and occult hepatitis B co-infection after liver transplantation

TitleNatural history of patients with recurrent chronic hepatitis C virus and occult hepatitis B co-infection after liver transplantation
Authors
KeywordsFibrosis progression
Liver transplantation
Occult HBV co-infection
Recurrent chronic hepatitis C virus
Relapsed infection due to HBV
Severe fibrosis
Issue Date2006
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/AJT
Citation
American Journal Of Transplantation, 2006, v. 6 n. 7, p. 1600-1608 How to Cite?
AbstractIt is uncertain whether occult hepatitis B virus co-infection will hasten progressive liver disease in chronic hepatitis C patients after liver transplantation. This study evaluated fibrosis progression and severe fibrosis in 118 consecutive hepatitis B surface antigen-negative patients with virological and histological evidence of recurrent chronic hepatitis C infection co-infected with occult hepatitis B virus after liver transplantation. HBV DNA was detected from serum at the time of recurrent chronic hepatitis C infection by polymerase chain reaction. Each subject underwent a repeat liver biopsy 5 years post-liver transplantation. Occult hepatitis B virus co-infection was present in 41 of the 118 (34.7%) patients. At 5 years post-liver transplantation, 13 of the 41 occult hepatitis B virus co-infected patients compared with 16 of the 77 patients without occult hepatitis B virus co-infection developed fibrosis progression (31.7% vs. 20.8%, respectively, p = 0.39). Eight of 41 the occult hepatitis B virus co-infected patients compared with 13 of the 77 patients without occult hepatitis B virus co-infection had severe fibrosis (19.5% vs. 16.9%, respectively, p = 0.97). In conclusion, occult hepatitis B virus co-infection in patients with recurrent chronic hepatitis C infection was not associated with accelerated fibrosis progression or severe fibrosis after liver transplantation. © 2006 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/83685
ISSN
2015 Impact Factor: 5.669
2015 SCImago Journal Rankings: 2.792
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHui, CKen_HK
dc.contributor.authorLau, Een_HK
dc.contributor.authorMonto, Aen_HK
dc.contributor.authorKim, Men_HK
dc.contributor.authorLuk, JMen_HK
dc.contributor.authorPoon, RTPen_HK
dc.contributor.authorLeung, Nen_HK
dc.contributor.authorLo, CMen_HK
dc.contributor.authorFan, STen_HK
dc.contributor.authorLau, GKKen_HK
dc.contributor.authorWright, TLen_HK
dc.date.accessioned2010-09-06T08:43:59Z-
dc.date.available2010-09-06T08:43:59Z-
dc.date.issued2006en_HK
dc.identifier.citationAmerican Journal Of Transplantation, 2006, v. 6 n. 7, p. 1600-1608en_HK
dc.identifier.issn1600-6135en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83685-
dc.description.abstractIt is uncertain whether occult hepatitis B virus co-infection will hasten progressive liver disease in chronic hepatitis C patients after liver transplantation. This study evaluated fibrosis progression and severe fibrosis in 118 consecutive hepatitis B surface antigen-negative patients with virological and histological evidence of recurrent chronic hepatitis C infection co-infected with occult hepatitis B virus after liver transplantation. HBV DNA was detected from serum at the time of recurrent chronic hepatitis C infection by polymerase chain reaction. Each subject underwent a repeat liver biopsy 5 years post-liver transplantation. Occult hepatitis B virus co-infection was present in 41 of the 118 (34.7%) patients. At 5 years post-liver transplantation, 13 of the 41 occult hepatitis B virus co-infected patients compared with 16 of the 77 patients without occult hepatitis B virus co-infection developed fibrosis progression (31.7% vs. 20.8%, respectively, p = 0.39). Eight of 41 the occult hepatitis B virus co-infected patients compared with 13 of the 77 patients without occult hepatitis B virus co-infection had severe fibrosis (19.5% vs. 16.9%, respectively, p = 0.97). In conclusion, occult hepatitis B virus co-infection in patients with recurrent chronic hepatitis C infection was not associated with accelerated fibrosis progression or severe fibrosis after liver transplantation. © 2006 The Authors.en_HK
dc.languageengen_HK
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/AJTen_HK
dc.relation.ispartofAmerican Journal of Transplantationen_HK
dc.subjectFibrosis progressionen_HK
dc.subjectLiver transplantationen_HK
dc.subjectOccult HBV co-infectionen_HK
dc.subjectRecurrent chronic hepatitis C virusen_HK
dc.subjectRelapsed infection due to HBVen_HK
dc.subjectSevere fibrosisen_HK
dc.titleNatural history of patients with recurrent chronic hepatitis C virus and occult hepatitis B co-infection after liver transplantationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1600-6135&volume=6&issue=7&spage=1600&epage=1608&date=2006&atitle=Natural+history+of+patients+with+recurrent+chronic+hepatitis+C+virus+and+occult+hepatitis+B+co-infection+after+liver+transplantationen_HK
dc.identifier.emailLuk, JM: jmluk@hkucc.hku.hken_HK
dc.identifier.emailPoon, RTP: poontp@hkucc.hku.hken_HK
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityLuk, JM=rp00349en_HK
dc.identifier.authorityPoon, RTP=rp00446en_HK
dc.identifier.authorityLo, CM=rp00412en_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/j.1600-6143.2006.01370.xen_HK
dc.identifier.pmid16827860-
dc.identifier.scopuseid_2-s2.0-33745348912en_HK
dc.identifier.hkuros117704en_HK
dc.identifier.hkuros120446-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33745348912&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.issue7en_HK
dc.identifier.spage1600en_HK
dc.identifier.epage1608en_HK
dc.identifier.isiWOS:000238465400016-
dc.publisher.placeDenmarken_HK
dc.identifier.scopusauthoridHui, CK=35082057900en_HK
dc.identifier.scopusauthoridLau, E=36631358500en_HK
dc.identifier.scopusauthoridMonto, A=7004552301en_HK
dc.identifier.scopusauthoridKim, M=49763365200en_HK
dc.identifier.scopusauthoridLuk, JM=7006777791en_HK
dc.identifier.scopusauthoridPoon, RTP=7103097223en_HK
dc.identifier.scopusauthoridLeung, N=26643107200en_HK
dc.identifier.scopusauthoridLo, CM=7401771672en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK
dc.identifier.scopusauthoridLau, GKK=7102301257en_HK
dc.identifier.scopusauthoridWright, TL=7402187126en_HK
dc.identifier.citeulike699210-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats