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Article: Effectiveness of Radiofrequency Ablation for Hepatocellular Carcinomas Larger Than 3 cm in Diameter

TitleEffectiveness of Radiofrequency Ablation for Hepatocellular Carcinomas Larger Than 3 cm in Diameter
Authors
Issue Date2004
PublisherAmerican Medical Association. The Journal's web site is located at http://www.archsurg.com
Citation
Archives Of Surgery, 2004, v. 139 n. 3, p. 281-287 How to Cite?
AbstractHypothesis: Radiofrequency ablation is a safe and effective treatment for hepatocellular carcinomas 3.1 to 8.0 cm in diameter. Design: Case series with prospective data collection. Setting: Tertiary referral center. Patients: Eighty-six patients with hepatocellular carcinoma treated with radiofrequency ablation from May 1, 2001, to December 31, 2002, were placed into categories of those with tumors 3 cm or smaller (group 1, n=51) and those with tumors 3.1 to 8.0 cm (group 2, n=35) in diameter. Interventions: Radiofrequency ablation was performed with a single or cluster cool-tip electrode. The choice of treatment route was based on tumor size and position. Main Outcome Measures: Complication, treatment mortality, and complete ablation rates. Results: Radiofrequency ablation was performed percutaneously in 26 patients in group 1 and 9 patients in group 2, with laparoscopy in 2 patients in group 1 and 1 patient in group 2, and with open operation in 23 patients in group 1 and 25 patients in group 2. The complication rates were 12% and 17% in group 1 and group 2, respectively (P=.48); treatment mortality rates were 0% and 3%, respectively (P=.41). Complete ablation rates after a single session of ablation assessed by means of computed tomography 1 month after treatment were 94% and 91% in group 1 and group 2, respectively (P=.68). Conclusion: Radiofrequency ablation is a safe and effective treatment for patients with hepatocellular carcinomas 3.1 to 8.0 cm in diameter.
Persistent Identifierhttp://hdl.handle.net/10722/83572
ISSN
2014 Impact Factor: 4.926
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPoon, RTPen_HK
dc.contributor.authorNg, KKCen_HK
dc.contributor.authorLam, CMen_HK
dc.contributor.authorAi, Ven_HK
dc.contributor.authorYuen, Jen_HK
dc.contributor.authorFan, STen_HK
dc.date.accessioned2010-09-06T08:42:38Z-
dc.date.available2010-09-06T08:42:38Z-
dc.date.issued2004en_HK
dc.identifier.citationArchives Of Surgery, 2004, v. 139 n. 3, p. 281-287en_HK
dc.identifier.issn0004-0010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83572-
dc.description.abstractHypothesis: Radiofrequency ablation is a safe and effective treatment for hepatocellular carcinomas 3.1 to 8.0 cm in diameter. Design: Case series with prospective data collection. Setting: Tertiary referral center. Patients: Eighty-six patients with hepatocellular carcinoma treated with radiofrequency ablation from May 1, 2001, to December 31, 2002, were placed into categories of those with tumors 3 cm or smaller (group 1, n=51) and those with tumors 3.1 to 8.0 cm (group 2, n=35) in diameter. Interventions: Radiofrequency ablation was performed with a single or cluster cool-tip electrode. The choice of treatment route was based on tumor size and position. Main Outcome Measures: Complication, treatment mortality, and complete ablation rates. Results: Radiofrequency ablation was performed percutaneously in 26 patients in group 1 and 9 patients in group 2, with laparoscopy in 2 patients in group 1 and 1 patient in group 2, and with open operation in 23 patients in group 1 and 25 patients in group 2. The complication rates were 12% and 17% in group 1 and group 2, respectively (P=.48); treatment mortality rates were 0% and 3%, respectively (P=.41). Complete ablation rates after a single session of ablation assessed by means of computed tomography 1 month after treatment were 94% and 91% in group 1 and group 2, respectively (P=.68). Conclusion: Radiofrequency ablation is a safe and effective treatment for patients with hepatocellular carcinomas 3.1 to 8.0 cm in diameter.en_HK
dc.languageengen_HK
dc.publisherAmerican Medical Association. The Journal's web site is located at http://www.archsurg.comen_HK
dc.relation.ispartofArchives of Surgeryen_HK
dc.titleEffectiveness of Radiofrequency Ablation for Hepatocellular Carcinomas Larger Than 3 cm in Diameteren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0004-0010&volume=139&issue=3&spage=281&epage=287&date=2004&atitle=Effectiveness+of+radiofrequency+ablation+for+hepatocellular+carcinoma+larger+than+3+cm+in+diameteren_HK
dc.identifier.emailPoon, RTP: poontp@hkucc.hku.hken_HK
dc.identifier.emailFan, ST: stfan@hku.hken_HK
dc.identifier.authorityPoon, RTP=rp00446en_HK
dc.identifier.authorityFan, ST=rp00355en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1001/archsurg.139.3.281en_HK
dc.identifier.pmid15006885-
dc.identifier.scopuseid_2-s2.0-1442336120en_HK
dc.identifier.hkuros85937en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1442336120&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume139en_HK
dc.identifier.issue3en_HK
dc.identifier.spage281en_HK
dc.identifier.epage287en_HK
dc.identifier.isiWOS:000220105400009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridPoon, RTP=7103097223en_HK
dc.identifier.scopusauthoridNg, KKC=7403179075en_HK
dc.identifier.scopusauthoridLam, CM=7402989820en_HK
dc.identifier.scopusauthoridAi, V=6603342063en_HK
dc.identifier.scopusauthoridYuen, J=7102620431en_HK
dc.identifier.scopusauthoridFan, ST=7402678224en_HK

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