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Article: Non-curative surgery for colorectal cancer: Critical appraisal of outcomes

TitleNon-curative surgery for colorectal cancer: Critical appraisal of outcomes
Authors
KeywordsColorectal cancer
Palliative surgery
Issue Date2004
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00384/index.htm
Citation
International Journal Of Colorectal Disease, 2004, v. 19 n. 3, p. 197-202 How to Cite?
AbstractBackground and aims: The value of surgery for patients with incurable colorectal cancer is controversial. This study evaluated outcomes in patients undergoing non-curative surgery for colorectal cancer and aimed to identify patients who would benefit from palliative surgery. Patients and methods: Demographics, tumour characteristics, operating details and outcomes were reviewed for 180 patients undergoing surgery for incurable colorectal cancer; palliative resection was performed in 150 cases. Seventeen patients died in the postoperative period. Risk factors for postoperative mortality and poor survival were analysed with univariate and multivariate analysis. Results: Multivariate analysis showed that operative mortality was significantly higher in patients with non-resection surgery and in those with ascites. Median survival of patients with resection was significantly longer than in those without resection (30 vs. 17 weeks). Other independent factors that were significantly associated poor survival were the presence of ascites, presence of bilobar liver metastasis and absence of chemotherapy and/or radiation therapy. Conclusion: Non-curative surgery is associated with high mortality in patients without resection and in the presence of ascites. These two factors, together with the presence of bilobar liver metastasis and the absence of chemotherapy and/or radiation therapy, are associated with poor survival. In the presence of these factors the balance between the benefit and risk of surgery should be carefully considered before decision for operative treatment. © Springer-Verlag 2003.
Persistent Identifierhttp://hdl.handle.net/10722/83440
ISSN
2015 Impact Factor: 2.383
2015 SCImago Journal Rankings: 1.102
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLaw, WLen_HK
dc.contributor.authorChan, WFen_HK
dc.contributor.authorLee, YMen_HK
dc.contributor.authorChu, KWen_HK
dc.date.accessioned2010-09-06T08:41:04Z-
dc.date.available2010-09-06T08:41:04Z-
dc.date.issued2004en_HK
dc.identifier.citationInternational Journal Of Colorectal Disease, 2004, v. 19 n. 3, p. 197-202en_HK
dc.identifier.issn0179-1958en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83440-
dc.description.abstractBackground and aims: The value of surgery for patients with incurable colorectal cancer is controversial. This study evaluated outcomes in patients undergoing non-curative surgery for colorectal cancer and aimed to identify patients who would benefit from palliative surgery. Patients and methods: Demographics, tumour characteristics, operating details and outcomes were reviewed for 180 patients undergoing surgery for incurable colorectal cancer; palliative resection was performed in 150 cases. Seventeen patients died in the postoperative period. Risk factors for postoperative mortality and poor survival were analysed with univariate and multivariate analysis. Results: Multivariate analysis showed that operative mortality was significantly higher in patients with non-resection surgery and in those with ascites. Median survival of patients with resection was significantly longer than in those without resection (30 vs. 17 weeks). Other independent factors that were significantly associated poor survival were the presence of ascites, presence of bilobar liver metastasis and absence of chemotherapy and/or radiation therapy. Conclusion: Non-curative surgery is associated with high mortality in patients without resection and in the presence of ascites. These two factors, together with the presence of bilobar liver metastasis and the absence of chemotherapy and/or radiation therapy, are associated with poor survival. In the presence of these factors the balance between the benefit and risk of surgery should be carefully considered before decision for operative treatment. © Springer-Verlag 2003.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00384/index.htmen_HK
dc.relation.ispartofInternational Journal of Colorectal Diseaseen_HK
dc.subjectColorectal canceren_HK
dc.subjectPalliative surgeryen_HK
dc.titleNon-curative surgery for colorectal cancer: Critical appraisal of outcomesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0179-1958&volume=19&issue=3&spage=197&epage=202&date=2004&atitle=Non-curative+surgery+for+colorectal+cancer:+critical+appraisal+of+outcomes+en_HK
dc.identifier.emailLaw, WL: lawwl@hkucc.hku.hken_HK
dc.identifier.authorityLaw, WL=rp00436en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00384-003-0551-7en_HK
dc.identifier.pmid14618348-
dc.identifier.scopuseid_2-s2.0-1942435980en_HK
dc.identifier.hkuros91893en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1942435980&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue3en_HK
dc.identifier.spage197en_HK
dc.identifier.epage202en_HK
dc.identifier.isiWOS:000220562000004-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLaw, WL=7103147867en_HK
dc.identifier.scopusauthoridChan, WF=16315313900en_HK
dc.identifier.scopusauthoridLee, YM=8521465600en_HK
dc.identifier.scopusauthoridChu, KW=7402453653en_HK

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