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Article: Marginal versus joint Box-Cox transformation with applications to percentile curve construction for IgG subclasses and blood pressures

TitleMarginal versus joint Box-Cox transformation with applications to percentile curve construction for IgG subclasses and blood pressures
Authors
KeywordsBlood pressures
Box-Cox
IgG
Joint transformation
Percentile curves
Issue Date2003
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-6715/
Citation
Statistics In Medicine, 2003, v. 22 n. 3, p. 397-408 How to Cite?
AbstractWhen age-specific percentile curves are constructed for several correlated variables, the marginal method of handling one variable at a time has typically been used. We address the question, frequently asked by practitioners, of whether we can achieve efficiency gains by joint estimation. We focus on a simple but common method of Box-Cox transformation and assess the statistical impact of a joint transformation to multivariate normality on the percentile curve estimation for correlated variables. We find that there is little gain from the joint transformation for estimating percentiles around the median but a noticeable reduction in variances is possible for estimating extreme percentiles that are usually of main interest in medical and biological applications. Our study is motivated by problems in constructing percentile charts for IgG subclasses of children and for blood pressures in adult populations, both of which are discussed in the paper as examples, and yet our general findings are applicable to a wide range of other problems. Copyright © 2003 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/83074
ISSN
2015 Impact Factor: 1.533
2015 SCImago Journal Rankings: 1.811
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHe, Xen_HK
dc.contributor.authorNg, KWen_HK
dc.contributor.authorShi, Jen_HK
dc.date.accessioned2010-09-06T08:36:37Z-
dc.date.available2010-09-06T08:36:37Z-
dc.date.issued2003en_HK
dc.identifier.citationStatistics In Medicine, 2003, v. 22 n. 3, p. 397-408en_HK
dc.identifier.issn0277-6715en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83074-
dc.description.abstractWhen age-specific percentile curves are constructed for several correlated variables, the marginal method of handling one variable at a time has typically been used. We address the question, frequently asked by practitioners, of whether we can achieve efficiency gains by joint estimation. We focus on a simple but common method of Box-Cox transformation and assess the statistical impact of a joint transformation to multivariate normality on the percentile curve estimation for correlated variables. We find that there is little gain from the joint transformation for estimating percentiles around the median but a noticeable reduction in variances is possible for estimating extreme percentiles that are usually of main interest in medical and biological applications. Our study is motivated by problems in constructing percentile charts for IgG subclasses of children and for blood pressures in adult populations, both of which are discussed in the paper as examples, and yet our general findings are applicable to a wide range of other problems. Copyright © 2003 John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-6715/en_HK
dc.relation.ispartofStatistics in Medicineen_HK
dc.rightsStatistics in Medicine . Copyright © John Wiley & Sons Ltd.en_HK
dc.subjectBlood pressuresen_HK
dc.subjectBox-Coxen_HK
dc.subjectIgGen_HK
dc.subjectJoint transformationen_HK
dc.subjectPercentile curvesen_HK
dc.titleMarginal versus joint Box-Cox transformation with applications to percentile curve construction for IgG subclasses and blood pressuresen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0277-6715&volume=22&spage=397&epage=408&date=2003&atitle=Marginal+versus+joint+Box-Cox+transformation+with+applications+to+percentile+curve+construction+for+IgG+subclasses+and+blood+pressuresen_HK
dc.identifier.emailNg, KW: kaing@hkucc.hku.hken_HK
dc.identifier.authorityNg, KW=rp00765en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/sim.1305en_HK
dc.identifier.pmid12529871-
dc.identifier.scopuseid_2-s2.0-0037441442en_HK
dc.identifier.hkuros76442en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0037441442&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue3en_HK
dc.identifier.spage397en_HK
dc.identifier.epage408en_HK
dc.identifier.isiWOS:000180723000005-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridHe, X=7404407842en_HK
dc.identifier.scopusauthoridNg, KW=7403178774en_HK
dc.identifier.scopusauthoridShi, J=50062431200en_HK

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