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Article: A nonparametric inference procedure for an illness-death model

TitleA nonparametric inference procedure for an illness-death model
Authors
Issue Date1997
PublisherTaylor & Francis Inc. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/07362994.asp
Citation
Stochastic Analysis And Applications, 1997, v. 15 n. 1, p. 125-135 How to Cite?
AbstractMethods of nonparametric inference are proposed for a process with two transient and three absorbing states. It is assumed that the times of transitions between the transient states are unobservable. One area of application is in epidemiology where the transient states correspond to healthy and ill, while the absorbing states correspond to types of death. It is the time of onset of illness which is assumed unobservable. Here we use the martingale theory to make inference about the cumulative hazard rate of the onset of the disease. The assumption of equality of hazard rates from the other causes with or without the disease is not needed. Instead, an assumption of proportionality between the two rates is made. A simulation study is given to compare the suggested procedure and the Nelson-Aalen estimator which requires complete observation of process.
Persistent Identifierhttp://hdl.handle.net/10722/83025
ISSN
2015 Impact Factor: 0.63
2015 SCImago Journal Rankings: 0.590
References

 

DC FieldValueLanguage
dc.contributor.authorPaul, Yen_HK
dc.contributor.authorLam, KFen_HK
dc.date.accessioned2010-09-06T08:36:04Z-
dc.date.available2010-09-06T08:36:04Z-
dc.date.issued1997en_HK
dc.identifier.citationStochastic Analysis And Applications, 1997, v. 15 n. 1, p. 125-135en_HK
dc.identifier.issn0736-2994en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83025-
dc.description.abstractMethods of nonparametric inference are proposed for a process with two transient and three absorbing states. It is assumed that the times of transitions between the transient states are unobservable. One area of application is in epidemiology where the transient states correspond to healthy and ill, while the absorbing states correspond to types of death. It is the time of onset of illness which is assumed unobservable. Here we use the martingale theory to make inference about the cumulative hazard rate of the onset of the disease. The assumption of equality of hazard rates from the other causes with or without the disease is not needed. Instead, an assumption of proportionality between the two rates is made. A simulation study is given to compare the suggested procedure and the Nelson-Aalen estimator which requires complete observation of process.en_HK
dc.languageengen_HK
dc.publisherTaylor & Francis Inc. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/07362994.aspen_HK
dc.relation.ispartofStochastic Analysis and Applicationsen_HK
dc.titleA nonparametric inference procedure for an illness-death modelen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0736-2994&volume=15&issue=1&spage=125&epage=135&date=1997&atitle=A+nonparametric+inference+procedure+for+an+illness-death+modelen_HK
dc.identifier.emailLam, KF: hrntlkf@hkucc.hku.hken_HK
dc.identifier.authorityLam, KF=rp00718en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1080/07362999708809467-
dc.identifier.scopuseid_2-s2.0-0038909446en_HK
dc.identifier.hkuros24856en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038909446&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue1en_HK
dc.identifier.spage125en_HK
dc.identifier.epage135en_HK
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridPaul, Y=7004311894en_HK
dc.identifier.scopusauthoridLam, KF=8948421200en_HK

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