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Article: Blink rate, neurocognitive impairments, and symptoms in schizophrenia

TitleBlink rate, neurocognitive impairments, and symptoms in schizophrenia
Authors
Keywordsblink rate
dopamine system
neurological signs
neuropsychology
schizophrenia
Issue Date1996
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/biopsychiat
Citation
Biological Psychiatry, 1996, v. 40 n. 7, p. 597-603 How to Cite?
AbstractThis study addresses the relationship between blink rate (as a measure of central dopaminergic activity), symptoms, neuropsychological performance, as well as neurological signs in schizophrenia. Blink rate between schizophrenic patients and a matched control group was compared in both 'relaxed' and 'attentive' conditions. Blink rate was increased in schizophrenic patients in the 'relaxed' condition but not in the 'attentive' condition. The relationship between blink rate and clinical variables was examined in a larger sample of 204 patients. In both 'relaxed' and 'attentive' coaditions, blink rate was related to 'hallucinations', 'anxiety', negative symptoms, and neuroleptic dosage. Attention was a significant predictor only in the 'relaxed' condition. No other significant correlation was found between blink rate, neuropsychological impairments, and neurological signs. These findings suggest that blink rate is not related to neurocognitive impairments in schizophrenia.
Persistent Identifierhttp://hdl.handle.net/10722/81672
ISSN
2015 Impact Factor: 11.212
2015 SCImago Journal Rankings: 5.823
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorLam, LCWen_HK
dc.contributor.authorChen, RYLen_HK
dc.contributor.authorNguyen, DGHen_HK
dc.date.accessioned2010-09-06T08:20:36Z-
dc.date.available2010-09-06T08:20:36Z-
dc.date.issued1996en_HK
dc.identifier.citationBiological Psychiatry, 1996, v. 40 n. 7, p. 597-603en_HK
dc.identifier.issn0006-3223en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81672-
dc.description.abstractThis study addresses the relationship between blink rate (as a measure of central dopaminergic activity), symptoms, neuropsychological performance, as well as neurological signs in schizophrenia. Blink rate between schizophrenic patients and a matched control group was compared in both 'relaxed' and 'attentive' conditions. Blink rate was increased in schizophrenic patients in the 'relaxed' condition but not in the 'attentive' condition. The relationship between blink rate and clinical variables was examined in a larger sample of 204 patients. In both 'relaxed' and 'attentive' coaditions, blink rate was related to 'hallucinations', 'anxiety', negative symptoms, and neuroleptic dosage. Attention was a significant predictor only in the 'relaxed' condition. No other significant correlation was found between blink rate, neuropsychological impairments, and neurological signs. These findings suggest that blink rate is not related to neurocognitive impairments in schizophrenia.en_HK
dc.languageengen_HK
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/biopsychiaten_HK
dc.relation.ispartofBiological Psychiatryen_HK
dc.rightsBiological Psychiatry. Copyright © Elsevier Inc.en_HK
dc.subjectblink rateen_HK
dc.subjectdopamine systemen_HK
dc.subjectneurological signsen_HK
dc.subjectneuropsychologyen_HK
dc.subjectschizophreniaen_HK
dc.titleBlink rate, neurocognitive impairments, and symptoms in schizophreniaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0006-3223&volume=40&spage=597&epage=603&date=1996&atitle=Blink+Rate,+Neurocognitive+Impairments+and+Symptoms+in+Schizophreniaen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/0006-3223(95)00482-3en_HK
dc.identifier.pmid8886292-
dc.identifier.scopuseid_2-s2.0-0030272963en_HK
dc.identifier.hkuros21617en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030272963&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume40en_HK
dc.identifier.issue7en_HK
dc.identifier.spage597en_HK
dc.identifier.epage603en_HK
dc.identifier.isiWOS:A1996VJ92900005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridLam, LCW=7201984627en_HK
dc.identifier.scopusauthoridChen, RYL=16635066600en_HK
dc.identifier.scopusauthoridNguyen, DGH=7402147208en_HK

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