Article: The components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design

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TitleThe components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design
AuthorsChan, RCK1 2
Chen, EYH1
Cheung, EFC3
Chen, RYL1
Cheung, HK3
KeywordsExecutive function
Fractionation
Schizophrenia
Supervisory attention
Issue Date2006
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
CitationSchizophrenia Research, 2006, v. 81 n. 2-3, p. 173-189 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.schres.2005.08.011
AbstractWe examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/ disinhibition. The participants were also given tests of general intelligence and memory. We analysed the executive functioning performance of individual patients against normative data from our laboratory, and summary scores for all of the executive functioning components were computed. For each component, participants were classified as having impairment with a test performance of 1.5 standard deviations or more from the norm of the corresponding test. Of all of the participants, 27.8% (n = 25) demonstrated poor performance in all of the components, and 5.6 % (n = 5) exhibited intact or fair performance in all of the components. Furthermore, 18.9% (n = 17) showed intact or fair performance in one component, 16.7% (n = 15) in two components, 21.1% (n = 19) in three components and 10% (n = 9) in four components. The groups did not differ in education, gender or duration of illness, but the group that showed impaired performance in all of the components demonstrated the most severe psychotic symptoms after controlling for background intelligence, age and medication. The differential breakdown for the executive functioning performance across the participants suggests that the fractionation of central executive functioning occurs in schizophrenia. © 2005 Elsevier B.V. All rights reserved.
ISSN0920-9964
2011 Impact Factor: 4.748
2011 SCImago Journal Rankings: 0.249
DOIhttp://dx.doi.org/10.1016/j.schres.2005.08.011
ISI Accession Number IDWOS:000235231300007
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorChan, RCK
dc.contributor.authorChen, EYH
dc.contributor.authorCheung, EFC
dc.contributor.authorChen, RYL
dc.contributor.authorCheung, HK
dc.date.accessioned2010-09-06T08:20:21Z
dc.date.available2010-09-06T08:20:21Z
dc.date.issued2006
dc.description.abstractWe examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/ disinhibition. The participants were also given tests of general intelligence and memory. We analysed the executive functioning performance of individual patients against normative data from our laboratory, and summary scores for all of the executive functioning components were computed. For each component, participants were classified as having impairment with a test performance of 1.5 standard deviations or more from the norm of the corresponding test. Of all of the participants, 27.8% (n = 25) demonstrated poor performance in all of the components, and 5.6 % (n = 5) exhibited intact or fair performance in all of the components. Furthermore, 18.9% (n = 17) showed intact or fair performance in one component, 16.7% (n = 15) in two components, 21.1% (n = 19) in three components and 10% (n = 9) in four components. The groups did not differ in education, gender or duration of illness, but the group that showed impaired performance in all of the components demonstrated the most severe psychotic symptoms after controlling for background intelligence, age and medication. The differential breakdown for the executive functioning performance across the participants suggests that the fractionation of central executive functioning occurs in schizophrenia. © 2005 Elsevier B.V. All rights reserved.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationSchizophrenia Research, 2006, v. 81 n. 2-3, p. 173-189 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.schres.2005.08.011
dc.identifier.doihttp://dx.doi.org/10.1016/j.schres.2005.08.011
dc.identifier.epage189
dc.identifier.hkuros116244
dc.identifier.isiWOS:000235231300007
dc.identifier.issn0920-9964
2011 Impact Factor: 4.748
2011 SCImago Journal Rankings: 0.249
dc.identifier.issue2-3
dc.identifier.openurl
dc.identifier.pmid16188430
dc.identifier.scopuseid_2-s2.0-30844451588
dc.identifier.spage173
dc.identifier.urihttp://hdl.handle.net/10722/81651
dc.identifier.volume81
dc.languageeng
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
dc.publisher.placeNetherlands
dc.relation.ispartofSchizophrenia Research
dc.relation.referencesReferences in Scopus
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.
dc.subjectExecutive function
dc.subjectFractionation
dc.subjectSchizophrenia
dc.subjectSupervisory attention
dc.titleThe components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. Sun Yat-Sen University
  3. Castle Peak Hospital Hong Kong