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Article: The components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design
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TitleThe components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design
 
AuthorsChan, RCK2 1
Chen, EYH1
Cheung, EFC3
Chen, RYL1
Cheung, HK3
 
KeywordsExecutive function
Fractionation
Schizophrenia
Supervisory attention
 
Issue Date2006
 
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
 
CitationSchizophrenia Research, 2006, v. 81 n. 2-3, p. 173-189 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.schres.2005.08.011
 
AbstractWe examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/ disinhibition. The participants were also given tests of general intelligence and memory. We analysed the executive functioning performance of individual patients against normative data from our laboratory, and summary scores for all of the executive functioning components were computed. For each component, participants were classified as having impairment with a test performance of 1.5 standard deviations or more from the norm of the corresponding test. Of all of the participants, 27.8% (n = 25) demonstrated poor performance in all of the components, and 5.6 % (n = 5) exhibited intact or fair performance in all of the components. Furthermore, 18.9% (n = 17) showed intact or fair performance in one component, 16.7% (n = 15) in two components, 21.1% (n = 19) in three components and 10% (n = 9) in four components. The groups did not differ in education, gender or duration of illness, but the group that showed impaired performance in all of the components demonstrated the most severe psychotic symptoms after controlling for background intelligence, age and medication. The differential breakdown for the executive functioning performance across the participants suggests that the fractionation of central executive functioning occurs in schizophrenia. © 2005 Elsevier B.V. All rights reserved.
 
ISSN0920-9964
2012 Impact Factor: 4.59
2012 SCImago Journal Rankings: 2.139
 
DOIhttp://dx.doi.org/10.1016/j.schres.2005.08.011
 
ISI Accession Number IDWOS:000235231300007
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorChan, RCK
 
dc.contributor.authorChen, EYH
 
dc.contributor.authorCheung, EFC
 
dc.contributor.authorChen, RYL
 
dc.contributor.authorCheung, HK
 
dc.date.accessioned2010-09-06T08:20:21Z
 
dc.date.available2010-09-06T08:20:21Z
 
dc.date.issued2006
 
dc.description.abstractWe examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/ disinhibition. The participants were also given tests of general intelligence and memory. We analysed the executive functioning performance of individual patients against normative data from our laboratory, and summary scores for all of the executive functioning components were computed. For each component, participants were classified as having impairment with a test performance of 1.5 standard deviations or more from the norm of the corresponding test. Of all of the participants, 27.8% (n = 25) demonstrated poor performance in all of the components, and 5.6 % (n = 5) exhibited intact or fair performance in all of the components. Furthermore, 18.9% (n = 17) showed intact or fair performance in one component, 16.7% (n = 15) in two components, 21.1% (n = 19) in three components and 10% (n = 9) in four components. The groups did not differ in education, gender or duration of illness, but the group that showed impaired performance in all of the components demonstrated the most severe psychotic symptoms after controlling for background intelligence, age and medication. The differential breakdown for the executive functioning performance across the participants suggests that the fractionation of central executive functioning occurs in schizophrenia. © 2005 Elsevier B.V. All rights reserved.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationSchizophrenia Research, 2006, v. 81 n. 2-3, p. 173-189 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.schres.2005.08.011
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.schres.2005.08.011
 
dc.identifier.epage189
 
dc.identifier.hkuros116244
 
dc.identifier.isiWOS:000235231300007
 
dc.identifier.issn0920-9964
2012 Impact Factor: 4.59
2012 SCImago Journal Rankings: 2.139
 
dc.identifier.issue2-3
 
dc.identifier.openurl
 
dc.identifier.pmid16188430
 
dc.identifier.scopuseid_2-s2.0-30844451588
 
dc.identifier.spage173
 
dc.identifier.urihttp://hdl.handle.net/10722/81651
 
dc.identifier.volume81
 
dc.languageeng
 
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
 
dc.publisher.placeNetherlands
 
dc.relation.ispartofSchizophrenia Research
 
dc.relation.referencesReferences in Scopus
 
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.
 
dc.subjectExecutive function
 
dc.subjectFractionation
 
dc.subjectSchizophrenia
 
dc.subjectSupervisory attention
 
dc.titleThe components of executive functioning in a cohort of patients with chronic schizophrenia: A multiple single-case study design
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. Sun Yat-Sen University
  3. Castle Peak Hospital Hong Kong