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Article: Determinants of seizure threshold of electroconvulsive therapy in Chinese

TitleDeterminants of seizure threshold of electroconvulsive therapy in Chinese
Authors
KeywordsChinese
Electroconvulsive therapy
Seizure threshold
Issue Date2006
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ectjournal.com
Citation
Journal Of Ect, 2006, v. 22 n. 2, p. 100-102 How to Cite?
AbstractOBJECTIVES: Debates continue whether dose-titration, formula-based or fixed-dosage method should be used during ECT. Regardless of the dosing method used, the range and the determinants of seizure threshold in different ethnic groups are useful clinical information. METHOD: Seizure threshold was quantified at the first ECT session using standardized dose titration and anesthetic protocols in 165 Chinese patients. One-hundred and five patients were treated with bilateral ECT and 60 with unilateral ECT. RESULTS: The mean seizure threshold was 95.9 mC (range = 32-403 mC). The mean and range of seizure threshold for bilateral ECT were 115.1 mC and 48-403 mC, for unilateral ECT, the mean and range were 62.1 mC and 32-192 mC. Stepwise regression analysis showed that electrode placement and age were the two most important predictors of seizure threshold and accounted for 32 and 20% of its variance respectively. Of lesser significance greater body mass index and concurrent use of antiepileptic were associated with higher seizure threshold. Unlike previous Western studies, we showed that gender had no significant relationship with seizure threshold for the total sample and unilateral ECT while for bilateral ECT interpretation is limited by the higher starting dose in men. CONCLUSION: Our finding added to the database on ECT in different ethnic groups and would be useful for the clinical practice of ECT in Chinese. Copyright © 2006 by Lippincott Williams & Wilkins.
Persistent Identifierhttp://hdl.handle.net/10722/81623
ISSN
2015 Impact Factor: 1.833
2015 SCImago Journal Rankings: 0.784
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChung, KFen_HK
dc.date.accessioned2010-09-06T08:20:00Z-
dc.date.available2010-09-06T08:20:00Z-
dc.date.issued2006en_HK
dc.identifier.citationJournal Of Ect, 2006, v. 22 n. 2, p. 100-102en_HK
dc.identifier.issn1095-0680en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81623-
dc.description.abstractOBJECTIVES: Debates continue whether dose-titration, formula-based or fixed-dosage method should be used during ECT. Regardless of the dosing method used, the range and the determinants of seizure threshold in different ethnic groups are useful clinical information. METHOD: Seizure threshold was quantified at the first ECT session using standardized dose titration and anesthetic protocols in 165 Chinese patients. One-hundred and five patients were treated with bilateral ECT and 60 with unilateral ECT. RESULTS: The mean seizure threshold was 95.9 mC (range = 32-403 mC). The mean and range of seizure threshold for bilateral ECT were 115.1 mC and 48-403 mC, for unilateral ECT, the mean and range were 62.1 mC and 32-192 mC. Stepwise regression analysis showed that electrode placement and age were the two most important predictors of seizure threshold and accounted for 32 and 20% of its variance respectively. Of lesser significance greater body mass index and concurrent use of antiepileptic were associated with higher seizure threshold. Unlike previous Western studies, we showed that gender had no significant relationship with seizure threshold for the total sample and unilateral ECT while for bilateral ECT interpretation is limited by the higher starting dose in men. CONCLUSION: Our finding added to the database on ECT in different ethnic groups and would be useful for the clinical practice of ECT in Chinese. Copyright © 2006 by Lippincott Williams & Wilkins.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.ectjournal.comen_HK
dc.relation.ispartofJournal of ECTen_HK
dc.rightsThe Journal of Electroconvulsive Therapy. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subjectChineseen_HK
dc.subjectElectroconvulsive therapyen_HK
dc.subjectSeizure thresholden_HK
dc.titleDeterminants of seizure threshold of electroconvulsive therapy in Chineseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1095-0680&volume=22&issue=2&spage=100&epage=102&date=2006&atitle=Determinants+of+seizure+threshold+of+electroconvulsive+therapy+in+Chineseen_HK
dc.identifier.emailChung, KF: kfchung@hkucc.hku.hken_HK
dc.identifier.authorityChung, KF=rp00377en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00124509-200606000-00004en_HK
dc.identifier.pmid16801823-
dc.identifier.scopuseid_2-s2.0-33748107835en_HK
dc.identifier.hkuros118937en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33748107835&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue2en_HK
dc.identifier.spage100en_HK
dc.identifier.epage102en_HK
dc.identifier.isiWOS:000238720500003-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridChung, KF=7404086681en_HK

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