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Article: Distribution of symptom dimensions across Kraepelinian divisions

TitleDistribution of symptom dimensions across Kraepelinian divisions
Authors
Issue Date2006
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
Citation
British Journal Of Psychiatry, 2006, v. 189 OCT., p. 346-353 How to Cite?
AbstractBackground: Dimensional structures are established for many psychiatric diagnoses, but dimensions have not been compared between diagnostic groups. Aims: To examine the structure of dimensions in psychosis, to analyse their correlations with disease characteristics and to assess the relative contribution of dimensions v. diagnosis in explaining these characteristics. Method: Factor analysis of the OPCRIT items of 191 Maudsley Family Study patients with schizophrenia, mood disorders with psychosis, schizoaffective disorder, and other psychotic illnesses, followed by regression of disease characteristics from factor scores and diagnosis. Results: Five factors were identified (mania, reality distortion, depression, disorganisation, negative); all were more variable in schizophrenia than in affective psychosis. Mania was the best discriminator between schizophrenia and affective psychosis; the negative factor was strongly correlated with poor premorbid functioning, insidious onset and worse course. Dimensions explained more of the disease characteristics than did diagnosis, but the explanatory power of the latter was also high. Conclusions: Kraepelinian diagnostic categories suffice for understanding illness characteristics, but the use of dimensions adds substantial information. Declaration of interest: None. Funding detailed in Acknowledgements.
Persistent Identifierhttp://hdl.handle.net/10722/81532
ISSN
2015 Impact Factor: 7.06
2015 SCImago Journal Rankings: 2.674
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorDikeos, DGen_HK
dc.contributor.authorWickham, Hen_HK
dc.contributor.authorMcDonald, Cen_HK
dc.contributor.authorWalshe, Men_HK
dc.contributor.authorSigmundsson, Ten_HK
dc.contributor.authorBramon, Een_HK
dc.contributor.authorGrech, Aen_HK
dc.contributor.authorToulopoulou, Ten_HK
dc.contributor.authorMurray, Ren_HK
dc.contributor.authorSham, PCen_HK
dc.date.accessioned2010-09-06T08:18:56Z-
dc.date.available2010-09-06T08:18:56Z-
dc.date.issued2006en_HK
dc.identifier.citationBritish Journal Of Psychiatry, 2006, v. 189 OCT., p. 346-353en_HK
dc.identifier.issn0007-1250en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81532-
dc.description.abstractBackground: Dimensional structures are established for many psychiatric diagnoses, but dimensions have not been compared between diagnostic groups. Aims: To examine the structure of dimensions in psychosis, to analyse their correlations with disease characteristics and to assess the relative contribution of dimensions v. diagnosis in explaining these characteristics. Method: Factor analysis of the OPCRIT items of 191 Maudsley Family Study patients with schizophrenia, mood disorders with psychosis, schizoaffective disorder, and other psychotic illnesses, followed by regression of disease characteristics from factor scores and diagnosis. Results: Five factors were identified (mania, reality distortion, depression, disorganisation, negative); all were more variable in schizophrenia than in affective psychosis. Mania was the best discriminator between schizophrenia and affective psychosis; the negative factor was strongly correlated with poor premorbid functioning, insidious onset and worse course. Dimensions explained more of the disease characteristics than did diagnosis, but the explanatory power of the latter was also high. Conclusions: Kraepelinian diagnostic categories suffice for understanding illness characteristics, but the use of dimensions adds substantial information. Declaration of interest: None. Funding detailed in Acknowledgements.en_HK
dc.languageengen_HK
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/en_HK
dc.relation.ispartofBritish Journal of Psychiatryen_HK
dc.titleDistribution of symptom dimensions across Kraepelinian divisionsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1250&volume=189&spage=346&epage=353&date=2006&atitle=Distribution+of+symptom+dimension+across+Kraepelinian+divisionsen_HK
dc.identifier.emailToulopoulou, T: timothea@hku.hken_HK
dc.identifier.emailSham, PC: pcsham@hku.hken_HK
dc.identifier.authorityToulopoulou, T=rp01542en_HK
dc.identifier.authoritySham, PC=rp00459en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1192/bjp.bp.105.017251en_HK
dc.identifier.pmid17012658-
dc.identifier.scopuseid_2-s2.0-33750210042en_HK
dc.identifier.hkuros133437en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33750210042&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume189en_HK
dc.identifier.issueOCT.en_HK
dc.identifier.spage346en_HK
dc.identifier.epage353en_HK
dc.identifier.isiWOS:000241585100008-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridDikeos, DG=6701448812en_HK
dc.identifier.scopusauthoridWickham, H=6701762103en_HK
dc.identifier.scopusauthoridMcDonald, C=8749594800en_HK
dc.identifier.scopusauthoridWalshe, M=8855469300en_HK
dc.identifier.scopusauthoridSigmundsson, T=6602171613en_HK
dc.identifier.scopusauthoridBramon, E=8089378900en_HK
dc.identifier.scopusauthoridGrech, A=6602744459en_HK
dc.identifier.scopusauthoridToulopoulou, T=8855468700en_HK
dc.identifier.scopusauthoridMurray, R=35406239400en_HK
dc.identifier.scopusauthoridSham, PC=34573429300en_HK

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