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- Publisher Website: 10.1016/j.csda.2006.11.012
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Article: Constrained unidimensional scaling with application to genomics
Title | Constrained unidimensional scaling with application to genomics |
---|---|
Authors | |
Keywords | Constraints Genomics Least squares problem Linkage disequilibrium Nonnegativity Unidimensional scaling |
Issue Date | 2007 |
Publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/csda |
Citation | Computational Statistics And Data Analysis, 2007, v. 52 n. 1, p. 201-210 How to Cite? |
Abstract | A constrained unidimensional scaling model where the objects are required to be placed in a given order on the real line, is studied. A procedure formulated as a least squares problem with nonnegativity is considered to solve this problem. An application to linkage disequilibrium (LD) maps for human genome is presented to demonstrate the proposed model. The LD maps are also constructed for four populations from Hapmap data sets, and analyze some of their similarities. © 2006 Elsevier B.V. All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/81525 |
ISSN | 2023 Impact Factor: 1.5 2023 SCImago Journal Rankings: 1.008 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ao, SI | en_HK |
dc.contributor.author | Ng, MK | en_HK |
dc.contributor.author | Sham, PC | en_HK |
dc.date.accessioned | 2010-09-06T08:18:50Z | - |
dc.date.available | 2010-09-06T08:18:50Z | - |
dc.date.issued | 2007 | en_HK |
dc.identifier.citation | Computational Statistics And Data Analysis, 2007, v. 52 n. 1, p. 201-210 | en_HK |
dc.identifier.issn | 0167-9473 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/81525 | - |
dc.description.abstract | A constrained unidimensional scaling model where the objects are required to be placed in a given order on the real line, is studied. A procedure formulated as a least squares problem with nonnegativity is considered to solve this problem. An application to linkage disequilibrium (LD) maps for human genome is presented to demonstrate the proposed model. The LD maps are also constructed for four populations from Hapmap data sets, and analyze some of their similarities. © 2006 Elsevier B.V. All rights reserved. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Elsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/csda | en_HK |
dc.relation.ispartof | Computational Statistics and Data Analysis | en_HK |
dc.rights | Computational Statistics & Data Analysis. Copyright © Elsevier BV. | en_HK |
dc.subject | Constraints | en_HK |
dc.subject | Genomics | en_HK |
dc.subject | Least squares problem | en_HK |
dc.subject | Linkage disequilibrium | en_HK |
dc.subject | Nonnegativity | en_HK |
dc.subject | Unidimensional scaling | en_HK |
dc.title | Constrained unidimensional scaling with application to genomics | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0167-9473&volume=52&spage=201&epage=210&date=2007&atitle=Constrained+unidimensional+scaling+with+application+to+genomics. | en_HK |
dc.identifier.email | Sham, PC: pcsham@hku.hk | en_HK |
dc.identifier.authority | Sham, PC=rp00459 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/j.csda.2006.11.012 | en_HK |
dc.identifier.scopus | eid_2-s2.0-34548223685 | en_HK |
dc.identifier.hkuros | 151616 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-34548223685&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 52 | en_HK |
dc.identifier.issue | 1 | en_HK |
dc.identifier.spage | 201 | en_HK |
dc.identifier.epage | 210 | en_HK |
dc.identifier.isi | WOS:000249912400016 | - |
dc.publisher.place | Netherlands | en_HK |
dc.identifier.scopusauthorid | Ao, SI=8581155100 | en_HK |
dc.identifier.scopusauthorid | Ng, MK=34571761900 | en_HK |
dc.identifier.scopusauthorid | Sham, PC=34573429300 | en_HK |
dc.identifier.issnl | 0167-9473 | - |