Article: Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China
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- Publisher Website: 10.1192/bjp.bp.108.055301
- Scopus: eid_2-s2.0-68549107765
- PMID: 19648542
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| Title | Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Authors | Ran, MS5 Chan, CLW2 Chen, EYH2 Mao, WJ3 Hu, SH3 Tang, CP1 Lin, FR1 Conwell, Y4 | ||||||||||
| Issue Date | 2009 | ||||||||||
| Publisher | Royal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/ | ||||||||||
| Citation | British Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131 [How to Cite?] DOI: http://dx.doi.org/10.1192/bjp.bp.108.055301 | ||||||||||
| Abstract | Background: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries. | ||||||||||
| ISSN | 0007-1250 2011 Impact Factor: 6.619 2011 SCImago Journal Rankings: 0.300 | ||||||||||
| DOI | http://dx.doi.org/10.1192/bjp.bp.108.055301 | ||||||||||
| ISI Accession Number ID | WOS:000268691700006
Funding Information: The 1994 Chengdu study was supported by a grant from the China Medical Board in New York (CMB, 92-557; MZ Xiang, PI). This work was supported in part by HKJC Centre for Suicide Research and Prevention, HKU, and ICOHRTA grant D43 TW05814 (E.D. Caine, PI) and GRIP 1 R01 TW007260-01 (M.S. Ran, PI) from the Fogarty International Center of NIH. | ||||||||||
| References | References in Scopus |
| dc.contributor.author | Ran, MS | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| dc.contributor.author | Chan, CLW | ||||||||||
| dc.contributor.author | Chen, EYH | ||||||||||
| dc.contributor.author | Mao, WJ | ||||||||||
| dc.contributor.author | Hu, SH | ||||||||||
| dc.contributor.author | Tang, CP | ||||||||||
| dc.contributor.author | Lin, FR | ||||||||||
| dc.contributor.author | Conwell, Y | ||||||||||
| dc.date.accessioned | 2010-09-06T08:18:28Z | ||||||||||
| dc.date.available | 2010-09-06T08:18:28Z | ||||||||||
| dc.date.issued | 2009 | ||||||||||
| dc.description.abstract | Background: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries. | ||||||||||
| dc.description.nature | Link_to_subscribed_fulltext | ||||||||||
| dc.identifier.citation | British Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131 [How to Cite?] DOI: http://dx.doi.org/10.1192/bjp.bp.108.055301 | ||||||||||
| dc.identifier.doi | http://dx.doi.org/10.1192/bjp.bp.108.055301 | ||||||||||
| dc.identifier.epage | 131 | ||||||||||
| dc.identifier.hkuros | 162041 | ||||||||||
| dc.identifier.isi | WOS:000268691700006
Funding Information: The 1994 Chengdu study was supported by a grant from the China Medical Board in New York (CMB, 92-557; MZ Xiang, PI). This work was supported in part by HKJC Centre for Suicide Research and Prevention, HKU, and ICOHRTA grant D43 TW05814 (E.D. Caine, PI) and GRIP 1 R01 TW007260-01 (M.S. Ran, PI) from the Fogarty International Center of NIH. | ||||||||||
| dc.identifier.issn | 0007-1250 2011 Impact Factor: 6.619 2011 SCImago Journal Rankings: 0.300 | ||||||||||
| dc.identifier.issue | 2 | ||||||||||
| dc.identifier.openurl | | ||||||||||
| dc.identifier.pmid | 19648542 | ||||||||||
| dc.identifier.scopus | eid_2-s2.0-68549107765 | ||||||||||
| dc.identifier.spage | 126 | ||||||||||
| dc.identifier.uri | http://hdl.handle.net/10722/81497 | ||||||||||
| dc.identifier.volume | 195 | ||||||||||
| dc.language | eng | ||||||||||
| dc.publisher | Royal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/ | ||||||||||
| dc.publisher.place | United Kingdom | ||||||||||
| dc.relation.ispartof | British Journal of Psychiatry | ||||||||||
| dc.relation.references | References in Scopus | ||||||||||
| dc.title | Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China | ||||||||||
| dc.type | Article |
Author Affiliations
- Xinjin Mental Hospital
- The University of Hong Kong
- Chengdu Mental Health Center
- University of Rochester Medical Center
- University of Guam