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Article: Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China

TitleDifferences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China
Authors
Issue Date2009
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
Citation
British Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131 How to Cite?
AbstractBackground: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries.
Persistent Identifierhttp://hdl.handle.net/10722/81497
ISSN
2014 Impact Factor: 7.991
2014 SCImago Journal Rankings: 2.634
PubMed Central ID
ISI Accession Number ID
Funding AgencyGrant Number
HKJC Centre for Suicide Research and Prevention
HKU
ICOHRTAD43 TW05814
Fogarty International Center of NIHGRIP 1 R01TW007260-01
Funding Information:

The 1994 Chengdu study was supported by a grant from the China Medical Board in New York (CMB, 92-557; MZ Xiang, PI). This work was supported in part by HKJC Centre for Suicide Research and Prevention, HKU, and ICOHRTA grant D43 TW05814 (E.D. Caine, PI) and GRIP 1 R01 TW007260-01 (M.S. Ran, PI) from the Fogarty International Center of NIH.

References

 

DC FieldValueLanguage
dc.contributor.authorRan, MSen_HK
dc.contributor.authorChan, CLWen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorMao, WJen_HK
dc.contributor.authorHu, SHen_HK
dc.contributor.authorTang, CPen_HK
dc.contributor.authorLin, FRen_HK
dc.contributor.authorConwell, Yen_HK
dc.date.accessioned2010-09-06T08:18:28Z-
dc.date.available2010-09-06T08:18:28Z-
dc.date.issued2009en_HK
dc.identifier.citationBritish Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131en_HK
dc.identifier.issn0007-1250en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81497-
dc.description.abstractBackground: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries.en_HK
dc.languageengen_HK
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/en_HK
dc.relation.ispartofBritish Journal of Psychiatryen_HK
dc.titleDifferences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural Chinaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1250&volume=195 &issue=2&spage=126&epage=131&date=2009&atitle=Differences+in+mortality+and+suicidal+behaviour+between+treated+and+never-treated+people+with+schizophrenia+in+rural+Chinaen_HK
dc.identifier.emailRan, MS: msran@hku.hken_HK
dc.identifier.emailChan, CLW: cecichan@hkucc.hku.hken_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.authorityRan, MS=rp01788en_HK
dc.identifier.authorityChan, CLW=rp00579en_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1192/bjp.bp.108.055301en_HK
dc.identifier.pmid19648542en_HK
dc.identifier.pmcidPMC2801819-
dc.identifier.scopuseid_2-s2.0-68549107765en_HK
dc.identifier.hkuros162041en_HK
dc.identifier.hkuros235231-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-68549107765&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume195en_HK
dc.identifier.issue2en_HK
dc.identifier.spage126en_HK
dc.identifier.epage131en_HK
dc.identifier.isiWOS:000268691700006-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridRan, MS=7006797666en_HK
dc.identifier.scopusauthoridChan, CLW=35274549700en_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridMao, WJ=12041418900en_HK
dc.identifier.scopusauthoridHu, SH=24178657000en_HK
dc.identifier.scopusauthoridTang, CP=35275973900en_HK
dc.identifier.scopusauthoridLin, FR=35311004500en_HK
dc.identifier.scopusauthoridConwell, Y=7006293352en_HK

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