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Article: Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China
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TitleDifferences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China
 
AuthorsRan, MS5
Chan, CLW2
Chen, EYH2
Mao, WJ3
Hu, SH3
Tang, CP1
Lin, FR1
Conwell, Y4
 
Issue Date2009
 
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
 
CitationBritish Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131 [How to Cite?]
DOI: http://dx.doi.org/10.1192/bjp.bp.108.055301
 
AbstractBackground: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries.
 
ISSN0007-1250
2013 Impact Factor: 7.343
 
DOIhttp://dx.doi.org/10.1192/bjp.bp.108.055301
 
PubMed Central IDPMC2801819
 
ISI Accession Number IDWOS:000268691700006
Funding AgencyGrant Number
HKJC Centre for Suicide Research and Prevention
HKU
ICOHRTAD43 TW05814
Fogarty International Center of NIHGRIP 1 R01TW007260-01
Funding Information:

The 1994 Chengdu study was supported by a grant from the China Medical Board in New York (CMB, 92-557; MZ Xiang, PI). This work was supported in part by HKJC Centre for Suicide Research and Prevention, HKU, and ICOHRTA grant D43 TW05814 (E.D. Caine, PI) and GRIP 1 R01 TW007260-01 (M.S. Ran, PI) from the Fogarty International Center of NIH.

 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorRan, MS
 
dc.contributor.authorChan, CLW
 
dc.contributor.authorChen, EYH
 
dc.contributor.authorMao, WJ
 
dc.contributor.authorHu, SH
 
dc.contributor.authorTang, CP
 
dc.contributor.authorLin, FR
 
dc.contributor.authorConwell, Y
 
dc.date.accessioned2010-09-06T08:18:28Z
 
dc.date.available2010-09-06T08:18:28Z
 
dc.date.issued2009
 
dc.description.abstractBackground: Many people with schizophrenia remain untreated in the community. Long-term mortality and suicidal behaviour among never-treated individuals with schizophrenia in the community are unknown. Aims: To explore 10-year mortality and suicidal behaviour among never-treated individuals with schizophrenia. Method: We used data from a 10-year prospective follow-up study (1994-2004) among people with schizophrenia in xinjin County, Chengdu, China. Results: The mortality rate for never-treated individuals with schizophrenia was 2761 per 100 000 person-years during follow-up. There were no significant differences of rates of suicide and all-cause mortality between never-treated and treated individuals. The standardised mortality ratio (SMR) for never-treated people was 10.4 (95% Cl 7.2-15.2) and for treated individuals 6.5 (95% Cl 5.2-8.5). Compared with treated people, never-treated individuals were more likely to be older, poorer, have a longer duration of illness, marked symptoms and fewer family members. Conclusions: The never-treated individuals have similar mortality to and a higher proportion of marked symptoms than treated people, which may reflect the poor outcome of the individuals without treatment. The higher rates of mortality, homelessness and never being treated among people with schizophrenia in low- and middle-income nations might challenge presumed wisdom about schizophrenia outcomes in these countries.
 
dc.description.naturelink_to_OA_fulltext
 
dc.identifier.citationBritish Journal Of Psychiatry, 2009, v. 195 n. 2, p. 126-131 [How to Cite?]
DOI: http://dx.doi.org/10.1192/bjp.bp.108.055301
 
dc.identifier.doihttp://dx.doi.org/10.1192/bjp.bp.108.055301
 
dc.identifier.epage131
 
dc.identifier.hkuros162041
 
dc.identifier.isiWOS:000268691700006
Funding AgencyGrant Number
HKJC Centre for Suicide Research and Prevention
HKU
ICOHRTAD43 TW05814
Fogarty International Center of NIHGRIP 1 R01TW007260-01
Funding Information:

The 1994 Chengdu study was supported by a grant from the China Medical Board in New York (CMB, 92-557; MZ Xiang, PI). This work was supported in part by HKJC Centre for Suicide Research and Prevention, HKU, and ICOHRTA grant D43 TW05814 (E.D. Caine, PI) and GRIP 1 R01 TW007260-01 (M.S. Ran, PI) from the Fogarty International Center of NIH.

 
dc.identifier.issn0007-1250
2013 Impact Factor: 7.343
 
dc.identifier.issue2
 
dc.identifier.openurl
 
dc.identifier.pmcidPMC2801819
 
dc.identifier.pmid19648542
 
dc.identifier.scopuseid_2-s2.0-68549107765
 
dc.identifier.spage126
 
dc.identifier.urihttp://hdl.handle.net/10722/81497
 
dc.identifier.volume195
 
dc.languageeng
 
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofBritish Journal of Psychiatry
 
dc.relation.referencesReferences in Scopus
 
dc.titleDifferences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China
 
dc.typeArticle
 
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<contributor.author>Lin, FR</contributor.author>
<contributor.author>Conwell, Y</contributor.author>
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Author Affiliations
  1. Xinjin Mental Hospital
  2. The University of Hong Kong
  3. Chengdu Mental Health Center
  4. University of Rochester Medical Center
  5. University of Guam