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Article: Executive dysfunctions in schizophrenia: Relationships to clinical manifestation

TitleExecutive dysfunctions in schizophrenia: Relationships to clinical manifestation
Authors
KeywordsExecutive functions
Schizophrenia
Supervisory attentional system
Issue Date2004
PublisherDr Dietrich Steinkopff Verlag. The Journal's web site is located at http://www.link.springer.de/link/service/journals/00406/index.htm
Citation
European Archives Of Psychiatry And Clinical Neuroscience, 2004, v. 254 n. 4, p. 256-262 How to Cite?
AbstractStudies suggest that executive functions in patients with schizophrenia are markedly impaired as compared with normal controls. Most previous studies employed tests of executive functions adopted from frontal lobe neuropsychological paradigms based on lesion studies. This study employed several more recently developed theory-driven tests of executive functions addressing the construct of the supervisory attentional system. We explore the pattern of executive function impairment using factor analysis and subsequently investigate the relationships between these executive function factors and the clinical features in a sample of chronic schizophrenic patients. A total of 51 patients with chronic schizophrenia were recruited. The Sustained Attention Response to Task (SART), Six Elements Test (SET) and Hayling Sentence Completion Test (HSC) were used to assess executive functions. Three factors were identified within the executive function tests: 1) The "semantic inhibition factor" comprised items in the HSC, 2) the "action/attention inhibition" factor comprised the SART commission error and the SET rule-breaking score and 3) the"output generation factor" comprised the SET raw score and the correct SART response. Significant relationships were found between these derived factors and clinical features after partialling out the confounding effect of age, education and illness duration. The three theory-based tests of executive function were shown to have good construct validity among the group of chronic schizophrenic patients.
Persistent Identifierhttp://hdl.handle.net/10722/81492
ISSN
2015 Impact Factor: 4.113
2015 SCImago Journal Rankings: 1.454
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChan, RCKen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorCheung, EFCen_HK
dc.contributor.authorCheung, HKen_HK
dc.date.accessioned2010-09-06T08:18:25Z-
dc.date.available2010-09-06T08:18:25Z-
dc.date.issued2004en_HK
dc.identifier.citationEuropean Archives Of Psychiatry And Clinical Neuroscience, 2004, v. 254 n. 4, p. 256-262en_HK
dc.identifier.issn0940-1334en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81492-
dc.description.abstractStudies suggest that executive functions in patients with schizophrenia are markedly impaired as compared with normal controls. Most previous studies employed tests of executive functions adopted from frontal lobe neuropsychological paradigms based on lesion studies. This study employed several more recently developed theory-driven tests of executive functions addressing the construct of the supervisory attentional system. We explore the pattern of executive function impairment using factor analysis and subsequently investigate the relationships between these executive function factors and the clinical features in a sample of chronic schizophrenic patients. A total of 51 patients with chronic schizophrenia were recruited. The Sustained Attention Response to Task (SART), Six Elements Test (SET) and Hayling Sentence Completion Test (HSC) were used to assess executive functions. Three factors were identified within the executive function tests: 1) The "semantic inhibition factor" comprised items in the HSC, 2) the "action/attention inhibition" factor comprised the SART commission error and the SET rule-breaking score and 3) the"output generation factor" comprised the SET raw score and the correct SART response. Significant relationships were found between these derived factors and clinical features after partialling out the confounding effect of age, education and illness duration. The three theory-based tests of executive function were shown to have good construct validity among the group of chronic schizophrenic patients.en_HK
dc.languageengen_HK
dc.publisherDr Dietrich Steinkopff Verlag. The Journal's web site is located at http://www.link.springer.de/link/service/journals/00406/index.htmen_HK
dc.relation.ispartofEuropean Archives of Psychiatry and Clinical Neuroscienceen_HK
dc.subjectExecutive functionsen_HK
dc.subjectSchizophreniaen_HK
dc.subjectSupervisory attentional systemen_HK
dc.titleExecutive dysfunctions in schizophrenia: Relationships to clinical manifestationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0940-1334&volume=254&spage=256&epage=262&date=2003&atitle=Executive+dysfunctions+in+schizophrenia:+relationships+to+clinical+manifestationsen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00406-004-0492-3en_HK
dc.identifier.pmid15309397-
dc.identifier.scopuseid_2-s2.0-4644294559en_HK
dc.identifier.hkuros88887en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-4644294559&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume254en_HK
dc.identifier.issue4en_HK
dc.identifier.spage256en_HK
dc.identifier.epage262en_HK
dc.identifier.isiWOS:000223310600011-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridChan, RCK=35236280300en_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridCheung, EFC=7006522469en_HK
dc.identifier.scopusauthoridCheung, HK=7201839420en_HK

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