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Article: Negative symptoms, neurological signs and neuropsychological impairments in 204 Hong Kong Chinese patients with schizophrenia

TitleNegative symptoms, neurological signs and neuropsychological impairments in 204 Hong Kong Chinese patients with schizophrenia
Authors
Issue Date1996
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
Citation
British Journal Of Psychiatry, 1996, v. 168 FEB., p. 227-233 How to Cite?
AbstractBackground. Studies of the relationship between negative symptoms, neuropsychological impairments and neurological signs in schizophrenia have yielded inconsistent results. In addition, little attention has been directed to address the extent of cultural modulation of negative symptoms. Method. We carried out cross-cultural validation of the High Royds Evaluation of Negativity Scale (HEN) in 50 Hong Kong Chinese patients with schizophrenia. We then investigated the relationship between negative symptoms, neurological signs and neuropsychological impairment in 204 patients. Results. Good interrater reliability, internal reliability, convergent and discriminant validity were found with the HEN. The HEN contained four factors corresponding to 'behaviour', 'functioning', 'thought' and 'appearance'. Negative symptoms were correlated with semantic fluency but not with Wisconsin Card Sorting Test performance or sustained attention. Negative symptoms were also correlated with tardive dyskinesia and catalonia but not with soft neurological signs. Conclusions. Cross-cultural robustness of the negative symptoms construct is supported. Association of negative symptoms with a specific profile of neurocognitive impairment suggests diversity within deficit domains in schizophrenia.
Persistent Identifierhttp://hdl.handle.net/10722/81468
ISSN
2015 Impact Factor: 7.06
2015 SCImago Journal Rankings: 2.674
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorLam, LCWen_HK
dc.contributor.authorChen, RYLen_HK
dc.contributor.authorNguyen, DGHen_HK
dc.date.accessioned2010-09-06T08:18:07Z-
dc.date.available2010-09-06T08:18:07Z-
dc.date.issued1996en_HK
dc.identifier.citationBritish Journal Of Psychiatry, 1996, v. 168 FEB., p. 227-233en_HK
dc.identifier.issn0007-1250en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81468-
dc.description.abstractBackground. Studies of the relationship between negative symptoms, neuropsychological impairments and neurological signs in schizophrenia have yielded inconsistent results. In addition, little attention has been directed to address the extent of cultural modulation of negative symptoms. Method. We carried out cross-cultural validation of the High Royds Evaluation of Negativity Scale (HEN) in 50 Hong Kong Chinese patients with schizophrenia. We then investigated the relationship between negative symptoms, neurological signs and neuropsychological impairment in 204 patients. Results. Good interrater reliability, internal reliability, convergent and discriminant validity were found with the HEN. The HEN contained four factors corresponding to 'behaviour', 'functioning', 'thought' and 'appearance'. Negative symptoms were correlated with semantic fluency but not with Wisconsin Card Sorting Test performance or sustained attention. Negative symptoms were also correlated with tardive dyskinesia and catalonia but not with soft neurological signs. Conclusions. Cross-cultural robustness of the negative symptoms construct is supported. Association of negative symptoms with a specific profile of neurocognitive impairment suggests diversity within deficit domains in schizophrenia.en_HK
dc.languageengen_HK
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/en_HK
dc.relation.ispartofBritish Journal of Psychiatryen_HK
dc.titleNegative symptoms, neurological signs and neuropsychological impairments in 204 Hong Kong Chinese patients with schizophreniaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-1250&volume=168&spage=227&epage=233&date=1996&atitle=Negative+Symptoms,+Neurological+Signs+and+Neuropsychological+Impairments+in+204+Hong+Kong+Chinese+Patients+with+Schizophreniaen_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.authorityChen, EYH=rp00392en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid8837915-
dc.identifier.scopuseid_2-s2.0-0030070914en_HK
dc.identifier.hkuros21710en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030070914&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume168en_HK
dc.identifier.issueFEB.en_HK
dc.identifier.spage227en_HK
dc.identifier.epage233en_HK
dc.identifier.isiWOS:A1996TU73500016-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChen, EYH=7402315729en_HK
dc.identifier.scopusauthoridLam, LCW=7201984627en_HK
dc.identifier.scopusauthoridChen, RYL=16635066600en_HK
dc.identifier.scopusauthoridNguyen, DGH=7402147208en_HK

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