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Article: The role of secretin in the cerebellum

TitleThe role of secretin in the cerebellum
Authors
KeywordsCerebellum
Neurotrophic factor
Retrograde messenger
Secretin
Synaptic plasticity
Issue Date2006
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14734222.asp
Citation
Cerebellum, 2006, v. 5 n. 1, p. 43-48 How to Cite?
AbstractThere is increasing interest in the role played by secretin in the central nervous system. Recent evidence suggests that this peptide is widely expressed in the brain but some areas, notably the cerebellum, show a prominent expression of the peptide and its specific receptor. In this article we summarize our current understanding of the expression pattern and action of secretin in the cerebellum. We discuss the findings supporting the endogenous release of this peptide from Purkinje neurons and its role as a retrograde messenger modulating GABAergic synaptic transmission via multiple mechanisms. In addition, we would like to propose other possible, but still to be confirmed, functions of secretin in the cerebellum..
Persistent Identifierhttp://hdl.handle.net/10722/81305
ISSN
2015 Impact Factor: 2.429
2015 SCImago Journal Rankings: 1.662
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYung, Wen_HK
dc.contributor.authorChan, Yen_HK
dc.contributor.authorChow, Ben_HK
dc.contributor.authorWang, Jen_HK
dc.date.accessioned2010-09-06T08:16:09Z-
dc.date.available2010-09-06T08:16:09Z-
dc.date.issued2006en_HK
dc.identifier.citationCerebellum, 2006, v. 5 n. 1, p. 43-48en_HK
dc.identifier.issn1473-4222en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81305-
dc.description.abstractThere is increasing interest in the role played by secretin in the central nervous system. Recent evidence suggests that this peptide is widely expressed in the brain but some areas, notably the cerebellum, show a prominent expression of the peptide and its specific receptor. In this article we summarize our current understanding of the expression pattern and action of secretin in the cerebellum. We discuss the findings supporting the endogenous release of this peptide from Purkinje neurons and its role as a retrograde messenger modulating GABAergic synaptic transmission via multiple mechanisms. In addition, we would like to propose other possible, but still to be confirmed, functions of secretin in the cerebellum..en_HK
dc.languageengen_HK
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/14734222.aspen_HK
dc.relation.ispartofCerebellumen_HK
dc.rightsThe Cerebellum. Copyright © Informa Healthcare.en_HK
dc.subjectCerebellumen_HK
dc.subjectNeurotrophic factoren_HK
dc.subjectRetrograde messengeren_HK
dc.subjectSecretinen_HK
dc.subjectSynaptic plasticityen_HK
dc.titleThe role of secretin in the cerebellumen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1473-4222&volume=5&spage=43&epage=48&date=2006&atitle=The+role+of+secretin+in+the+cerebellumen_HK
dc.identifier.emailChan, Y: yschan@hku.hken_HK
dc.identifier.emailChow, B: bkcc@hku.hken_HK
dc.identifier.authorityChan, Y=rp00318en_HK
dc.identifier.authorityChow, B=rp00681en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1080/14734220500416829en_HK
dc.identifier.pmid16527763en_HK
dc.identifier.scopuseid_2-s2.0-33646839294en_HK
dc.identifier.hkuros115211en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33646839294&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume5en_HK
dc.identifier.issue1en_HK
dc.identifier.spage43en_HK
dc.identifier.epage48en_HK
dc.identifier.isiWOS:000236551800007-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYung, W=7103137893en_HK
dc.identifier.scopusauthoridChan, Y=7403676627en_HK
dc.identifier.scopusauthoridChow, B=7102826193en_HK
dc.identifier.scopusauthoridWang, J=9841895000en_HK
dc.identifier.citeulike642288-

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