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Article: Melatonin: A chemical photoperiodic signal with clinical significance in humans

TitleMelatonin: A chemical photoperiodic signal with clinical significance in humans
Authors
Issue Date1998
PublisherChinese Medical Association. The Journal's web site is located at http://www.cmj.org/
Citation
Chinese Medical Journal, 1998, v. 111 n. 3, p. 197-203 How to Cite?
AbstractSecretion of pineal melatonin exhibits a diumal rhythm and a seasonal rhythm in humans. Night-time melatonin is high at 3-5 year-old and decreases with age. Many drugs and pathological conditions also change melatonin levels in the circulation. Melatonin has a mild sedative effect and has been used effectively in synchronizing the sleep-wake cycle of patients with sleep disorders. Immunoenhancing, anti-cancer, anti-aging and anti-oxidant effects of melatonin have been proposed. Recent studies suggest that melatonin receptors are present in central and peripheral tissues. The importance of melatonin receptors on the nervous, reproductive, immune and renal functions is implicated. Studies on the molecular biology, physiology and pathology of melatonin receptors in different tissues are progressing rapidly. The physiological and pathological changes in melatonin secretion, multifarious melatonin actions, and diverse melatonin receptors reported suggest that melatonin is photoperiodic signal with clinical significance in humans.
Persistent Identifierhttp://hdl.handle.net/10722/81268
ISSN
2015 Impact Factor: 0.957
2015 SCImago Journal Rankings: 0.428
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorPang, SFen_HK
dc.contributor.authorPang, CSen_HK
dc.contributor.authorPoon, AMSen_HK
dc.contributor.authorLee, PPNen_HK
dc.contributor.authorLiu, ZMen_HK
dc.contributor.authorShiu, SYWen_HK
dc.date.accessioned2010-09-06T08:15:44Z-
dc.date.available2010-09-06T08:15:44Z-
dc.date.issued1998en_HK
dc.identifier.citationChinese Medical Journal, 1998, v. 111 n. 3, p. 197-203en_HK
dc.identifier.issn0366-6999en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81268-
dc.description.abstractSecretion of pineal melatonin exhibits a diumal rhythm and a seasonal rhythm in humans. Night-time melatonin is high at 3-5 year-old and decreases with age. Many drugs and pathological conditions also change melatonin levels in the circulation. Melatonin has a mild sedative effect and has been used effectively in synchronizing the sleep-wake cycle of patients with sleep disorders. Immunoenhancing, anti-cancer, anti-aging and anti-oxidant effects of melatonin have been proposed. Recent studies suggest that melatonin receptors are present in central and peripheral tissues. The importance of melatonin receptors on the nervous, reproductive, immune and renal functions is implicated. Studies on the molecular biology, physiology and pathology of melatonin receptors in different tissues are progressing rapidly. The physiological and pathological changes in melatonin secretion, multifarious melatonin actions, and diverse melatonin receptors reported suggest that melatonin is photoperiodic signal with clinical significance in humans.en_HK
dc.languageengen_HK
dc.publisherChinese Medical Association. The Journal's web site is located at http://www.cmj.org/en_HK
dc.relation.ispartofChinese Medical Journalen_HK
dc.titleMelatonin: A chemical photoperiodic signal with clinical significance in humansen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0366-6999&volume=111&issue=3&spage=197&epage=203&date=1998&atitle=Melatonin:+a+chemical+photoperiodic+signal+with+clinical+significance+in+humansen_HK
dc.identifier.emailPoon, AMS: amspoon@hkucc.hku.hken_HK
dc.identifier.emailShiu, SYW: sywshiu@hkucc.hku.hken_HK
dc.identifier.authorityPoon, AMS=rp00354en_HK
dc.identifier.authorityShiu, SYW=rp00384en_HK
dc.description.naturelink_to_OA_fulltext-
dc.identifier.pmid10374414-
dc.identifier.scopuseid_2-s2.0-0031900975en_HK
dc.identifier.hkuros36807en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031900975&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume111en_HK
dc.identifier.issue3en_HK
dc.identifier.spage197en_HK
dc.identifier.epage203en_HK
dc.identifier.isiWOS:000072533500002-
dc.publisher.placeChinaen_HK
dc.identifier.scopusauthoridPang, SF=7402528719en_HK
dc.identifier.scopusauthoridPang, CS=7201425191en_HK
dc.identifier.scopusauthoridPoon, AMS=7103068868en_HK
dc.identifier.scopusauthoridLee, PPN=7406119629en_HK
dc.identifier.scopusauthoridLiu, ZM=7406671362en_HK
dc.identifier.scopusauthoridShiu, SYW=7005550655en_HK

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