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Article: An updated phylogenetic analysis of vertebrate melatonin receptor sequences: Reflection on the melatonin receptor nomenclature by the nomenclature subcommittee of the International Union of Pharmacology

TitleAn updated phylogenetic analysis of vertebrate melatonin receptor sequences: Reflection on the melatonin receptor nomenclature by the nomenclature subcommittee of the International Union of Pharmacology
Authors
KeywordsMelatonin receptor nomenclature
Melatonin receptor sequences
Phylogenetic analysis
Issue Date1998
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/NSG
Citation
Biological Signals And Receptors, 1998, v. 7 n. 4, p. 244-248 How to Cite?
AbstractIn the past few years, significant progress on melatonin receptor research has led to the discovery of a family of genetically related but pharmacologically distinctive G-protein-coupled receptors in the vertebrates. With increasing number of receptor clones being identified, there is a need for a system of classification and nomenclature for these receptor subtypes. Recently, an updated nomenclature system, which has renamed the existing mammalian melatonin receptor clones, has been proposed by the relevant subcommittee of the International Union of Pharmacology (NC-IUPHAR). However, the majority of receptor clones which have been identified in non-mammalian vertebrates are not clearly defined by this system. By performing phylogenetic analysis of both mammalian and non-mammalian melatonin receptor clones, we would like to propose a classification-nomenclature system for vertebrate melatonin receptors. Hopefully, our system, which incorporates genetic data as well as the pharmacological criteria that have been adopted by the NC-IUPHAR nomenclature system, will provide the framework for future development of a unified scheme of classification and nomenclature for melatonin receptors.
Persistent Identifierhttp://hdl.handle.net/10722/81263
ISSN
2003 Impact Factor: 3.5
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorShiu, SYWen_HK
dc.contributor.authorPang, SFen_HK
dc.date.accessioned2010-09-06T08:15:41Z-
dc.date.available2010-09-06T08:15:41Z-
dc.date.issued1998en_HK
dc.identifier.citationBiological Signals And Receptors, 1998, v. 7 n. 4, p. 244-248en_HK
dc.identifier.issn1422-4933en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81263-
dc.description.abstractIn the past few years, significant progress on melatonin receptor research has led to the discovery of a family of genetically related but pharmacologically distinctive G-protein-coupled receptors in the vertebrates. With increasing number of receptor clones being identified, there is a need for a system of classification and nomenclature for these receptor subtypes. Recently, an updated nomenclature system, which has renamed the existing mammalian melatonin receptor clones, has been proposed by the relevant subcommittee of the International Union of Pharmacology (NC-IUPHAR). However, the majority of receptor clones which have been identified in non-mammalian vertebrates are not clearly defined by this system. By performing phylogenetic analysis of both mammalian and non-mammalian melatonin receptor clones, we would like to propose a classification-nomenclature system for vertebrate melatonin receptors. Hopefully, our system, which incorporates genetic data as well as the pharmacological criteria that have been adopted by the NC-IUPHAR nomenclature system, will provide the framework for future development of a unified scheme of classification and nomenclature for melatonin receptors.en_HK
dc.languageengen_HK
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/NSGen_HK
dc.relation.ispartofBiological Signals and Receptorsen_HK
dc.rightsBiological Signals and Receptors. Copyright © S Karger AG.en_HK
dc.subjectMelatonin receptor nomenclatureen_HK
dc.subjectMelatonin receptor sequencesen_HK
dc.subjectPhylogenetic analysisen_HK
dc.titleAn updated phylogenetic analysis of vertebrate melatonin receptor sequences: Reflection on the melatonin receptor nomenclature by the nomenclature subcommittee of the International Union of Pharmacologyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1422-4933&volume=7&spage=244&epage=248&date=1998&atitle=An+updated+phylogenetic+analysis+of+vertebrate+melatonin+receptor+sequences:+Reflection+on+the+melatonin+receptor+nomenclature+by+the+Nomenclature+Subcommittee+of+the+International+Union+of+Pharmacologyen_HK
dc.identifier.emailShiu, SYW: sywshiu@hkucc.hku.hken_HK
dc.identifier.authorityShiu, SYW=rp00384en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid9730584-
dc.identifier.scopuseid_2-s2.0-0031662281en_HK
dc.identifier.hkuros38011en_HK
dc.identifier.volume7en_HK
dc.identifier.issue4en_HK
dc.identifier.spage244en_HK
dc.identifier.epage248en_HK
dc.identifier.isiWOS:000075823300005-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridShiu, SYW=7005550655en_HK
dc.identifier.scopusauthoridPang, SF=7402528719en_HK

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