File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: The effect of aging on ANP levels in the plasma, heart, and brain of rats

TitleThe effect of aging on ANP levels in the plasma, heart, and brain of rats
Authors
Issue Date1997
PublisherOxford University Press. The Journal's web site is located at http://biomed.gerontologyjournals.org/
Citation
Journals Of Gerontology - Series A Biological Sciences And Medical Sciences, 1997, v. 52 n. 5, p. B250-B254 How to Cite?
AbstractAtrial natriuretic peptide (ANP) is a hormone important in the cardiovascular system via its regulatory roles in sodium and water excretion, and in vasodilatation. Aging represents a major risk factor in the development of hypertension, a perturbation which may activate compensatory mechanisms. The influence of aging on the ANP levels in plasma, atria, ventricles, hypothalamus, and brainstem was evaluated by comparing young (3 mo), middle-aged (12 mo), and old (24 mo) rats. Plasma and ventricular ANP levels increased with age, while ANP content in the atria as well as hypothalamus decreased significantly. PreproANP mRNA contents increased with age in the ventricle but not in the atrium. It is suggested that the increase in plasma ANP levels in old rats is due to the in crease in ANP secretion from the atrium and the ventricle, partly as a result of an increase of release of ANP from hypothalamus.
Persistent Identifierhttp://hdl.handle.net/10722/81224
ISSN
2015 Impact Factor: 5.476
2015 SCImago Journal Rankings: 2.675
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWu, SQen_HK
dc.contributor.authorKwan, CYen_HK
dc.contributor.authorTang, Fen_HK
dc.date.accessioned2010-09-06T08:15:13Z-
dc.date.available2010-09-06T08:15:13Z-
dc.date.issued1997en_HK
dc.identifier.citationJournals Of Gerontology - Series A Biological Sciences And Medical Sciences, 1997, v. 52 n. 5, p. B250-B254en_HK
dc.identifier.issn1079-5006en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81224-
dc.description.abstractAtrial natriuretic peptide (ANP) is a hormone important in the cardiovascular system via its regulatory roles in sodium and water excretion, and in vasodilatation. Aging represents a major risk factor in the development of hypertension, a perturbation which may activate compensatory mechanisms. The influence of aging on the ANP levels in plasma, atria, ventricles, hypothalamus, and brainstem was evaluated by comparing young (3 mo), middle-aged (12 mo), and old (24 mo) rats. Plasma and ventricular ANP levels increased with age, while ANP content in the atria as well as hypothalamus decreased significantly. PreproANP mRNA contents increased with age in the ventricle but not in the atrium. It is suggested that the increase in plasma ANP levels in old rats is due to the in crease in ANP secretion from the atrium and the ventricle, partly as a result of an increase of release of ANP from hypothalamus.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://biomed.gerontologyjournals.org/en_HK
dc.relation.ispartofJournals of Gerontology - Series A Biological Sciences and Medical Sciencesen_HK
dc.titleThe effect of aging on ANP levels in the plasma, heart, and brain of ratsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0163-4372&volume=&spage=&epage=&date=1997&atitle=The+effect+of+aging+on+ANP+levels+in+the+plasma,heart+and++brain+of+ratsen_HK
dc.identifier.emailTang, F: ftang@hkucc.hku.hken_HK
dc.identifier.authorityTang, F=rp00327en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/gerona/52A.5.B250-
dc.identifier.pmid9310074-
dc.identifier.scopuseid_2-s2.0-0030750978en_HK
dc.identifier.hkuros26382en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0030750978&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume52en_HK
dc.identifier.issue5en_HK
dc.identifier.spageB250en_HK
dc.identifier.epageB254en_HK
dc.identifier.isiWOS:A1997XX36400005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWu, SQ=7407180073en_HK
dc.identifier.scopusauthoridKwan, CY=7201421224en_HK
dc.identifier.scopusauthoridTang, F=7201979770en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats