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Article: Towards rational and evidence-based use of melatonin in prostate cancer prevention and treatment

TitleTowards rational and evidence-based use of melatonin in prostate cancer prevention and treatment
Authors
KeywordsAndrogen
Chemoprevention
Melatonin
MT1 receptor
p27 Kip1
Prostate cancer
Prostate-specific antigen
Issue Date2007
PublisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPI
Citation
Journal Of Pineal Research, 2007, v. 43 n. 1, p. 1-9 How to Cite?
AbstractProstate cancer is a public health problem of the elderly men. It has been estimated that one in six men will develop prostate cancer in his lifetime in the USA. There is thus a huge clinical demand for effective therapies for the prevention and treatment of the disease. Here, the scientific evidence supporting the effectiveness of melatonin in inhibiting the development and progression of prostate cancer is reviewed. The rational use of melatonin in prostate cancer prevention, stabilization of clinically localized favourable-risk prostate cancer and palliative treatment of advanced or metastatic tumour is discussed within the context of the molecular pathogenesis of the disease. © 2007 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/81204
ISSN
2015 Impact Factor: 9.314
2015 SCImago Journal Rankings: 2.655
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorShiu, SYWen_HK
dc.date.accessioned2010-09-06T08:15:00Z-
dc.date.available2010-09-06T08:15:00Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal Of Pineal Research, 2007, v. 43 n. 1, p. 1-9en_HK
dc.identifier.issn0742-3098en_HK
dc.identifier.urihttp://hdl.handle.net/10722/81204-
dc.description.abstractProstate cancer is a public health problem of the elderly men. It has been estimated that one in six men will develop prostate cancer in his lifetime in the USA. There is thus a huge clinical demand for effective therapies for the prevention and treatment of the disease. Here, the scientific evidence supporting the effectiveness of melatonin in inhibiting the development and progression of prostate cancer is reviewed. The rational use of melatonin in prostate cancer prevention, stabilization of clinically localized favourable-risk prostate cancer and palliative treatment of advanced or metastatic tumour is discussed within the context of the molecular pathogenesis of the disease. © 2007 The Authors.en_HK
dc.languageengen_HK
dc.publisherBlackwell Munksgaard. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JPIen_HK
dc.relation.ispartofJournal of Pineal Researchen_HK
dc.subjectAndrogenen_HK
dc.subjectChemopreventionen_HK
dc.subjectMelatoninen_HK
dc.subjectMT1 receptoren_HK
dc.subjectp27 Kip1en_HK
dc.subjectProstate canceren_HK
dc.subjectProstate-specific antigenen_HK
dc.titleTowards rational and evidence-based use of melatonin in prostate cancer prevention and treatmenten_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0742-3098&volume=43&spage=1&epage=9&date=2007&atitle=Towards+rational+and+evidence-based+use+of+melatonin+in+prostate+cancer+prevention+and+treatmenten_HK
dc.identifier.emailShiu, SYW: sywshiu@hkucc.hku.hken_HK
dc.identifier.authorityShiu, SYW=rp00384en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1600-079X.2007.00451.xen_HK
dc.identifier.pmid17614829en_HK
dc.identifier.scopuseid_2-s2.0-34447125201en_HK
dc.identifier.hkuros132264en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34447125201&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume43en_HK
dc.identifier.issue1en_HK
dc.identifier.spage1en_HK
dc.identifier.epage9en_HK
dc.identifier.isiWOS:000247756900001-
dc.publisher.placeDenmarken_HK
dc.identifier.scopusauthoridShiu, SYW=7005550655en_HK
dc.identifier.citeulike1441429-

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