File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1143/JPSJ.67.3637
- Scopus: eid_2-s2.0-0032285163
- WOS: WOS:000076724400052
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Subthreshold Dynamics and Its Effect on Signal Transduction in a Neural System
Title | Subthreshold Dynamics and Its Effect on Signal Transduction in a Neural System |
---|---|
Authors | |
Keywords | Signal transduction Stochastic resonance Subthreshold dynamics |
Issue Date | 1998 |
Publisher | Institute of Pure and Applied Physics. The Journal's web site is located at http://www.ipap.jp/jpsj/index.htm |
Citation | Journal of the Physical Society of Japan, 1998, v. 67 n. 10, p. 3637-3644 How to Cite? |
Abstract | Subthreshold dynamics and its effect on signal transduction in a neural system are studied by using the Hindmarsh-Rose neuron model. Under a periodic stimulation, as the constant bias of the stimulus increases, the neuron exhibits subthreshold periodic and subthreshold chaotic responses, suprathreshold chaotic firing of spikes, and mode-locked firing. The phase diagram of the system is obtained. The dynamic behavior obtained is in agreement with experiments on the squid giant axon. In particular, the subthreshold periodic oscillatory state is related to a number of experimental results, such as those found in the neurons of the inferior olivary nucleus. More importantly, we also find that subthreshold chaotic responses play a role analogous to the internal deterministic noise, and can enhance weak signal transduction via a mechanism similar to stochastic resonance. |
Persistent Identifier | http://hdl.handle.net/10722/80532 |
ISSN | 2023 Impact Factor: 1.5 2023 SCImago Journal Rankings: 0.612 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wang, Y | en_HK |
dc.contributor.author | Wang, ZD | en_HK |
dc.contributor.author | Wang, W | en_HK |
dc.date.accessioned | 2010-09-06T08:07:29Z | - |
dc.date.available | 2010-09-06T08:07:29Z | - |
dc.date.issued | 1998 | en_HK |
dc.identifier.citation | Journal of the Physical Society of Japan, 1998, v. 67 n. 10, p. 3637-3644 | - |
dc.identifier.issn | 0031-9015 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/80532 | - |
dc.description.abstract | Subthreshold dynamics and its effect on signal transduction in a neural system are studied by using the Hindmarsh-Rose neuron model. Under a periodic stimulation, as the constant bias of the stimulus increases, the neuron exhibits subthreshold periodic and subthreshold chaotic responses, suprathreshold chaotic firing of spikes, and mode-locked firing. The phase diagram of the system is obtained. The dynamic behavior obtained is in agreement with experiments on the squid giant axon. In particular, the subthreshold periodic oscillatory state is related to a number of experimental results, such as those found in the neurons of the inferior olivary nucleus. More importantly, we also find that subthreshold chaotic responses play a role analogous to the internal deterministic noise, and can enhance weak signal transduction via a mechanism similar to stochastic resonance. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Institute of Pure and Applied Physics. The Journal's web site is located at http://www.ipap.jp/jpsj/index.htm | en_HK |
dc.relation.ispartof | Journal of the Physical Society of Japan | en_HK |
dc.subject | Signal transduction | en_HK |
dc.subject | Stochastic resonance | en_HK |
dc.subject | Subthreshold dynamics | en_HK |
dc.title | Subthreshold Dynamics and Its Effect on Signal Transduction in a Neural System | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0031-9015&volume=67&spage=3637&epage=3644&date=1998&atitle=Subthreshold+Dynamics+and+Its+Effect+on+Signal+Transduction+in+a+Neural+System | en_HK |
dc.identifier.email | Wang, ZD: zwang@hkucc.hku.hk | en_HK |
dc.identifier.authority | Wang, ZD=rp00802 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1143/JPSJ.67.3637 | - |
dc.identifier.scopus | eid_2-s2.0-0032285163 | en_HK |
dc.identifier.hkuros | 38919 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0032285163&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 67 | en_HK |
dc.identifier.issue | 10 | en_HK |
dc.identifier.spage | 3637 | en_HK |
dc.identifier.epage | 3644 | en_HK |
dc.identifier.isi | WOS:000076724400052 | - |
dc.publisher.place | Japan | en_HK |
dc.identifier.scopusauthorid | Wang, Y=7601487807 | en_HK |
dc.identifier.scopusauthorid | Wang, ZD=14828459100 | en_HK |
dc.identifier.scopusauthorid | Wang, W=36072896000 | en_HK |
dc.identifier.issnl | 0031-9015 | - |