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Article: A double-blind comparison of the effect on quality of life of a combination of vital substances including standardized ginseng G115 and placebo

TitleA double-blind comparison of the effect on quality of life of a combination of vital substances including standardized ginseng G115 and placebo
Authors
Issue Date1994
PublisherExcerpta Medica, Inc. The Journal's web site is located at http://www.elsevier.com/locate/curtheres
Citation
Current Therapeutic Research - Clinical And Experimental, 1994, v. 55 n. 1, p. 32-42 How to Cite?
AbstractThe effect on quality of life (QOL) of a combination of vital substances, including ginseng extract G115, was compared with that of placebo in a double-blind, randomized study with a duration of 12 weeks. Healthy, employed volunteers older than 25 years were included. QOL was evaluated in two standard, self-administered questionnaires, the Psychological General Well- Being (PGWB) index and the Sleep Dysfunction scale. In addition to these, bipolar adjectives in visual analogue scales (VAS) were used to quantify changes in other behavioral aspects. In all, 185 subjects taking placebo and 205 subjects taking the combination of active substances completed the study. Both the combination and placebo groups improved their general well-being, but the improvement from baseline was more pronounced in those subjects taking the combination of active substances. According to the VAS scores, subjects receiving the combination of active substances improved significantly more in alertness (P = 0.05), relaxation (P = 0.02), appetite (P = 0.04), and overall score (P = 0.03). Among a subgroup of subjects with the 20% lowest scores at baseline, the combination improved both vitality (P = 0.03) and depressed mood (P = 0.05). It was concluded that despite the fact that healthy, employed subjects were evaluated, treatment with the combination of active substances had significant advantages over placebo therapy.
Persistent Identifierhttp://hdl.handle.net/10722/80136
ISSN
2012 Impact Factor: 0.446
2015 SCImago Journal Rankings: 0.519
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWiklund, Ien_HK
dc.contributor.authorKarlberg, Jen_HK
dc.contributor.authorLund, Ben_HK
dc.date.accessioned2010-09-06T08:02:49Z-
dc.date.available2010-09-06T08:02:49Z-
dc.date.issued1994en_HK
dc.identifier.citationCurrent Therapeutic Research - Clinical And Experimental, 1994, v. 55 n. 1, p. 32-42en_HK
dc.identifier.issn0011-393Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/80136-
dc.description.abstractThe effect on quality of life (QOL) of a combination of vital substances, including ginseng extract G115, was compared with that of placebo in a double-blind, randomized study with a duration of 12 weeks. Healthy, employed volunteers older than 25 years were included. QOL was evaluated in two standard, self-administered questionnaires, the Psychological General Well- Being (PGWB) index and the Sleep Dysfunction scale. In addition to these, bipolar adjectives in visual analogue scales (VAS) were used to quantify changes in other behavioral aspects. In all, 185 subjects taking placebo and 205 subjects taking the combination of active substances completed the study. Both the combination and placebo groups improved their general well-being, but the improvement from baseline was more pronounced in those subjects taking the combination of active substances. According to the VAS scores, subjects receiving the combination of active substances improved significantly more in alertness (P = 0.05), relaxation (P = 0.02), appetite (P = 0.04), and overall score (P = 0.03). Among a subgroup of subjects with the 20% lowest scores at baseline, the combination improved both vitality (P = 0.03) and depressed mood (P = 0.05). It was concluded that despite the fact that healthy, employed subjects were evaluated, treatment with the combination of active substances had significant advantages over placebo therapy.en_HK
dc.languageengen_HK
dc.publisherExcerpta Medica, Inc. The Journal's web site is located at http://www.elsevier.com/locate/curtheresen_HK
dc.relation.ispartofCurrent Therapeutic Research - Clinical and Experimentalen_HK
dc.titleA double-blind comparison of the effect on quality of life of a combination of vital substances including standardized ginseng G115 and placeboen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0011-393X&volume=55&spage=32&epage=42&date=1994&atitle=A+double-blind+comparison+of+the+effect+on+quality+of+life+of+a+combination+of+vital+substances+including+standardized+ginseng+G115+and+placeboen_HK
dc.identifier.emailKarlberg, J: jpekarl@hkucc.hku.hken_HK
dc.identifier.authorityKarlberg, J=rp00400en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/S0011-393X(05)80075-Xen_HK
dc.identifier.scopuseid_2-s2.0-0028047271en_HK
dc.identifier.hkuros30275en_HK
dc.identifier.volume55en_HK
dc.identifier.issue1en_HK
dc.identifier.spage32en_HK
dc.identifier.epage42en_HK
dc.identifier.isiWOS:A1994MT87900005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWiklund, I=7005656321en_HK
dc.identifier.scopusauthoridKarlberg, J=7005218406en_HK
dc.identifier.scopusauthoridLund, B=16157618800en_HK

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