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Article: Familial testotoxicosis in a Chinese family

TitleFamilial testotoxicosis in a Chinese family
Authors
Keywordsprecocious puberty
suppressed gonadotrophins
testotoxicosis
Issue Date1994
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00431/index.htm
Citation
European Journal Of Pediatrics, 1994, v. 153 n. 4, p. 241-244 How to Cite?
AbstractWe report two cases of 'familial testotoxicosis' in a family of Southern Chinese descent. The proband, an 8-year 4-month-old boy and his 35-year-old father both presented with early sexual development. In both cases the testicular volume was only 6 ml despite fully developed secondary sexual characteristics. Both patients had adult testosterone concentrations but a suppressed gonadotrophin response to gonadotrophin-releasing hormone. The suppressed gonadotrophin response to gonadotrophin-releasing hormone in the father suggests that autonomous gonadal production of sex steroid by the testes can persist well into adult life in some patients with familial testotoxicosis.
Persistent Identifierhttp://hdl.handle.net/10722/80093
ISSN
2015 Impact Factor: 1.791
2015 SCImago Journal Rankings: 0.772
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLim, YJen_HK
dc.contributor.authorLow, LCKen_HK
dc.date.accessioned2010-09-06T08:02:19Z-
dc.date.available2010-09-06T08:02:19Z-
dc.date.issued1994en_HK
dc.identifier.citationEuropean Journal Of Pediatrics, 1994, v. 153 n. 4, p. 241-244en_HK
dc.identifier.issn0340-6199en_HK
dc.identifier.urihttp://hdl.handle.net/10722/80093-
dc.description.abstractWe report two cases of 'familial testotoxicosis' in a family of Southern Chinese descent. The proband, an 8-year 4-month-old boy and his 35-year-old father both presented with early sexual development. In both cases the testicular volume was only 6 ml despite fully developed secondary sexual characteristics. Both patients had adult testosterone concentrations but a suppressed gonadotrophin response to gonadotrophin-releasing hormone. The suppressed gonadotrophin response to gonadotrophin-releasing hormone in the father suggests that autonomous gonadal production of sex steroid by the testes can persist well into adult life in some patients with familial testotoxicosis.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00431/index.htmen_HK
dc.relation.ispartofEuropean Journal of Pediatricsen_HK
dc.subjectprecocious pubertyen_HK
dc.subjectsuppressed gonadotrophinsen_HK
dc.subjecttestotoxicosisen_HK
dc.titleFamilial testotoxicosis in a Chinese familyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0340-6199&volume=153&spage=241&epage=244&date=1994&atitle=Familial+testotoxicosis+in+a+Chinese+familyen_HK
dc.identifier.emailLow, LCK: lcklow@hkucc.hku.hken_HK
dc.identifier.authorityLow, LCK=rp00337en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s004310050127en_HK
dc.identifier.pmid8194554-
dc.identifier.scopuseid_2-s2.0-0028206560en_HK
dc.identifier.hkuros31017en_HK
dc.identifier.volume153en_HK
dc.identifier.issue4en_HK
dc.identifier.spage241en_HK
dc.identifier.epage244en_HK
dc.identifier.isiWOS:A1994NC57300005-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridLim, YJ=16413395300en_HK
dc.identifier.scopusauthoridLow, LCK=7007049461en_HK

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