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Article: Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia
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TitleFusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia
 
AuthorsMa, Z5
Morris, SW5 4
Valentine, V5
L, M7
Herbrick, JA7
Cui, X5
Bouman, D6
Li, Y7
Mehta, PK5
Nizetic, D1
Kaneko, Y3
Chan, GCF2
Chan, LC2
Squire, J6
Scherer, SW6 7
Hitzler, JK7
 
Issue Date2001
 
PublisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
 
CitationNature Genetics, 2001, v. 28 n. 3, p. 220-221 [How to Cite?]
DOI: http://dx.doi.org/10.1038/90054
 
Abstractt(1;22) is the principal translocation of acute megakaryoblastic leukemias. Here we show this chromosomal rearrangement to result in the fusion of two novel genes, RNA-binding motif protein-15 (RBM15), an RNA recognition motif-encoding gene with homology to Drosophila spen, and Megakaryoblastic Leukemia-1 (MKL1), a gene encoding an SAP (SAF-A/B, Acinus and PIAS) DNA-binding domain.
 
ISSN1061-4036
2012 Impact Factor: 35.209
2012 SCImago Journal Rankings: 20.421
 
DOIhttp://dx.doi.org/10.1038/90054
 
ISI Accession Number IDWOS:000169656400013
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorMa, Z
 
dc.contributor.authorMorris, SW
 
dc.contributor.authorValentine, V
 
dc.contributor.authorL, M
 
dc.contributor.authorHerbrick, JA
 
dc.contributor.authorCui, X
 
dc.contributor.authorBouman, D
 
dc.contributor.authorLi, Y
 
dc.contributor.authorMehta, PK
 
dc.contributor.authorNizetic, D
 
dc.contributor.authorKaneko, Y
 
dc.contributor.authorChan, GCF
 
dc.contributor.authorChan, LC
 
dc.contributor.authorSquire, J
 
dc.contributor.authorScherer, SW
 
dc.contributor.authorHitzler, JK
 
dc.date.accessioned2010-09-06T08:01:36Z
 
dc.date.available2010-09-06T08:01:36Z
 
dc.date.issued2001
 
dc.description.abstractt(1;22) is the principal translocation of acute megakaryoblastic leukemias. Here we show this chromosomal rearrangement to result in the fusion of two novel genes, RNA-binding motif protein-15 (RBM15), an RNA recognition motif-encoding gene with homology to Drosophila spen, and Megakaryoblastic Leukemia-1 (MKL1), a gene encoding an SAP (SAF-A/B, Acinus and PIAS) DNA-binding domain.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationNature Genetics, 2001, v. 28 n. 3, p. 220-221 [How to Cite?]
DOI: http://dx.doi.org/10.1038/90054
 
dc.identifier.doihttp://dx.doi.org/10.1038/90054
 
dc.identifier.epage221
 
dc.identifier.hkuros67655
 
dc.identifier.isiWOS:000169656400013
 
dc.identifier.issn1061-4036
2012 Impact Factor: 35.209
2012 SCImago Journal Rankings: 20.421
 
dc.identifier.issue3
 
dc.identifier.openurl
 
dc.identifier.pmid11431691
 
dc.identifier.scopuseid_2-s2.0-0034941166
 
dc.identifier.spage220
 
dc.identifier.urihttp://hdl.handle.net/10722/80033
 
dc.identifier.volume28
 
dc.languageeng
 
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
 
dc.publisher.placeUnited States
 
dc.relation.ispartofNature Genetics
 
dc.relation.referencesReferences in Scopus
 
dc.subject.meshChromosomes, Human, Pair 1 - genetics
 
dc.subject.meshChromosomes, Human, Pair 22 - genetics
 
dc.subject.meshDNA-Binding Proteins - genetics
 
dc.subject.meshHumans
 
dc.subject.meshLeukemia, Megakaryoblastic, Acute - genetics
 
dc.subject.meshMolecular Sequence Data
 
dc.subject.meshOncogene Proteins, Fusion - genetics
 
dc.subject.meshRNA-Binding Proteins - genetics
 
dc.subject.meshTranslocation, Genetic
 
dc.titleFusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia
 
dc.typeArticle
 
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Author Affiliations
  1. School of Pharmacy University of London
  2. The University of Hong Kong
  3. Saitama Cancer Center
  4. University of Tennessee Health Science Center
  5. St. Jude Children Research Hospital
  6. University of Toronto
  7. Hospital for Sick Children University of Toronto