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Article: Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia

TitleFusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia
Authors
Issue Date2001
PublisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.com
Citation
Nature Genetics, 2001, v. 28 n. 3, p. 220-221 How to Cite?
Abstract
t(1;22) is the principal translocation of acute megakaryoblastic leukemias. Here we show this chromosomal rearrangement to result in the fusion of two novel genes, RNA-binding motif protein-15 (RBM15), an RNA recognition motif-encoding gene with homology to Drosophila spen, and Megakaryoblastic Leukemia-1 (MKL1), a gene encoding an SAP (SAF-A/B, Acinus and PIAS) DNA-binding domain.
Persistent Identifierhttp://hdl.handle.net/10722/80033
ISSN
2013 Impact Factor: 29.648
2013 SCImago Journal Rankings: 24.052
ISI Accession Number ID
References

 

Author Affiliations
  1. School of Pharmacy University of London
  2. The University of Hong Kong
  3. Saitama Cancer Center
  4. University of Tennessee Health Science Center
  5. St. Jude Children Research Hospital
  6. University of Toronto
  7. Hospital for Sick Children University of Toronto
DC FieldValueLanguage
dc.contributor.authorMa, Zen_HK
dc.contributor.authorMorris, SWen_HK
dc.contributor.authorValentine, Ven_HK
dc.contributor.authorL, Men_HK
dc.contributor.authorHerbrick, JAen_HK
dc.contributor.authorCui, Xen_HK
dc.contributor.authorBouman, Den_HK
dc.contributor.authorLi, Yen_HK
dc.contributor.authorMehta, PKen_HK
dc.contributor.authorNizetic, Den_HK
dc.contributor.authorKaneko, Yen_HK
dc.contributor.authorChan, GCFen_HK
dc.contributor.authorChan, LCen_HK
dc.contributor.authorSquire, Jen_HK
dc.contributor.authorScherer, SWen_HK
dc.contributor.authorHitzler, JKen_HK
dc.date.accessioned2010-09-06T08:01:36Z-
dc.date.available2010-09-06T08:01:36Z-
dc.date.issued2001en_HK
dc.identifier.citationNature Genetics, 2001, v. 28 n. 3, p. 220-221en_HK
dc.identifier.issn1061-4036en_HK
dc.identifier.urihttp://hdl.handle.net/10722/80033-
dc.description.abstractt(1;22) is the principal translocation of acute megakaryoblastic leukemias. Here we show this chromosomal rearrangement to result in the fusion of two novel genes, RNA-binding motif protein-15 (RBM15), an RNA recognition motif-encoding gene with homology to Drosophila spen, and Megakaryoblastic Leukemia-1 (MKL1), a gene encoding an SAP (SAF-A/B, Acinus and PIAS) DNA-binding domain.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.genetics.nature.comen_HK
dc.relation.ispartofNature Geneticsen_HK
dc.subject.meshChromosomes, Human, Pair 1 - geneticsen_HK
dc.subject.meshChromosomes, Human, Pair 22 - geneticsen_HK
dc.subject.meshDNA-Binding Proteins - geneticsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshLeukemia, Megakaryoblastic, Acute - geneticsen_HK
dc.subject.meshMolecular Sequence Dataen_HK
dc.subject.meshOncogene Proteins, Fusion - geneticsen_HK
dc.subject.meshRNA-Binding Proteins - geneticsen_HK
dc.subject.meshTranslocation, Geneticen_HK
dc.titleFusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemiaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1061-4036&volume=28&spage=220&epage=221&date=2001&atitle=Fusion+of+two+novel+genes,+RBM15+and+MKL1,+in+the+t(1;22)(p13;q13)+of+acute+megakaryoblastic+leukemiaen_HK
dc.identifier.emailChan, GCF:gcfchan@hkucc.hku.hken_HK
dc.identifier.emailChan, LC:chanlc@hkucc.hku.hken_HK
dc.identifier.authorityChan, GCF=rp00431en_HK
dc.identifier.authorityChan, LC=rp00373en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/90054en_HK
dc.identifier.pmid11431691en_HK
dc.identifier.scopuseid_2-s2.0-0034941166en_HK
dc.identifier.hkuros67655en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034941166&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issue3en_HK
dc.identifier.spage220en_HK
dc.identifier.epage221en_HK
dc.identifier.isiWOS:000169656400013-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridMa, Z=7403601189en_HK
dc.identifier.scopusauthoridMorris, SW=35430339000en_HK
dc.identifier.scopusauthoridValentine, V=7003857535en_HK
dc.identifier.scopusauthoridL, M=23060844800en_HK
dc.identifier.scopusauthoridHerbrick, JA=6602297751en_HK
dc.identifier.scopusauthoridCui, X=7401617040en_HK
dc.identifier.scopusauthoridBouman, D=6603372387en_HK
dc.identifier.scopusauthoridLi, Y=26662008200en_HK
dc.identifier.scopusauthoridMehta, PK=55197571100en_HK
dc.identifier.scopusauthoridNizetic, D=7003483313en_HK
dc.identifier.scopusauthoridKaneko, Y=34770419600en_HK
dc.identifier.scopusauthoridChan, GCF=16160154400en_HK
dc.identifier.scopusauthoridChan, LC=7403540707en_HK
dc.identifier.scopusauthoridSquire, J=7102094488en_HK
dc.identifier.scopusauthoridScherer, SW=35374654500en_HK
dc.identifier.scopusauthoridHitzler, JK=8773867300en_HK

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