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Conference Paper: Haemophilus influenzae type b infections in Hong Kong

TitleHaemophilus influenzae type b infections in Hong Kong
Authors
KeywordsHaemophilus influenzae
Haemophilus influenzae type b
Hong Kong
Meningitis
Issue Date1998
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.pidj.com
Citation
Pediatric Infectious Disease Journal, 1998, v. 17 n. 9 SUPPL., p. S165-S169 How to Cite?
AbstractA 5-year territory-wide retrospective survey of invasive Haemophilus influenzae type b (Hib) diseases in Hong Kong established that the annual incidence for children <5 years old was 2.7 per 100 000 [95% confidence interval (CI), 2.0 to 3.5]. However, the corresponding annual incidence in Vietnamese refugees in Hong Kong was 42.7 per 100 000 (95% CI 17.2 to 87.9), giving a relative risk of 18.5 (95% CI 8.3 to 41.0). The nasopharyngeal carriage rate of Hib was zero in 621 healthy Chinese children and 1.3% (95% CI 0.04 to 2.63%) in 300 healthy Vietnamese refugees 2 months to 5 years old in Hong Kong. The corresponding carriage rate of nontypable H. influenzae was 5.8% (95% CI 1.4 to 7.6%) in Chinese and 65.4% (95% CI 58.9 to 69.8) in Vietnamese. In a larger study of 1812 healthy Chinese children between 6 months and 5 years of age investigated by throat swabs, again no Hib was isolated but 141 children (7.8%) were found to be carriers of non-type b H. influenzae. In a study of 596 healthy Chinese children and adults, 25% had the protective level of anti-Hib antibody of >0.15 μg/ml by 1 year and 90% had reached > 0.15 μg/ml by 6 years of age. There was some evidence that these 'natural' antibodies against Hib in Hong Kong Chinese were cross- reacting antibodies against antigens on other encapsulated bacteria.
Persistent Identifierhttp://hdl.handle.net/10722/80022
ISSN
2015 Impact Factor: 2.587
2015 SCImago Journal Rankings: 1.416
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLau, YLen_HK
dc.contributor.authorYung, Ren_HK
dc.contributor.authorLow, Len_HK
dc.contributor.authorSung, Ren_HK
dc.contributor.authorLeung, CWen_HK
dc.contributor.authorLee, WHen_HK
dc.date.accessioned2010-09-06T08:01:28Z-
dc.date.available2010-09-06T08:01:28Z-
dc.date.issued1998en_HK
dc.identifier.citationPediatric Infectious Disease Journal, 1998, v. 17 n. 9 SUPPL., p. S165-S169en_HK
dc.identifier.issn0891-3668en_HK
dc.identifier.urihttp://hdl.handle.net/10722/80022-
dc.description.abstractA 5-year territory-wide retrospective survey of invasive Haemophilus influenzae type b (Hib) diseases in Hong Kong established that the annual incidence for children <5 years old was 2.7 per 100 000 [95% confidence interval (CI), 2.0 to 3.5]. However, the corresponding annual incidence in Vietnamese refugees in Hong Kong was 42.7 per 100 000 (95% CI 17.2 to 87.9), giving a relative risk of 18.5 (95% CI 8.3 to 41.0). The nasopharyngeal carriage rate of Hib was zero in 621 healthy Chinese children and 1.3% (95% CI 0.04 to 2.63%) in 300 healthy Vietnamese refugees 2 months to 5 years old in Hong Kong. The corresponding carriage rate of nontypable H. influenzae was 5.8% (95% CI 1.4 to 7.6%) in Chinese and 65.4% (95% CI 58.9 to 69.8) in Vietnamese. In a larger study of 1812 healthy Chinese children between 6 months and 5 years of age investigated by throat swabs, again no Hib was isolated but 141 children (7.8%) were found to be carriers of non-type b H. influenzae. In a study of 596 healthy Chinese children and adults, 25% had the protective level of anti-Hib antibody of >0.15 μg/ml by 1 year and 90% had reached > 0.15 μg/ml by 6 years of age. There was some evidence that these 'natural' antibodies against Hib in Hong Kong Chinese were cross- reacting antibodies against antigens on other encapsulated bacteria.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.pidj.comen_HK
dc.relation.ispartofPediatric Infectious Disease Journalen_HK
dc.rightsThe Pediatric Infectious Disease Journal. Copyright © Lippincott Williams & Wilkins.en_HK
dc.subjectHaemophilus influenzaeen_HK
dc.subjectHaemophilus influenzae type ben_HK
dc.subjectHong Kongen_HK
dc.subjectMeningitisen_HK
dc.titleHaemophilus influenzae type b infections in Hong Kongen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0891-3668&volume=17&issue=9&spage=S165&epage=9&date=1998&atitle=Haemophilus+influenzae+type+b+infections+in+Hong+Kongen_HK
dc.identifier.emailLau, YL: lauylung@hku.hken_HK
dc.identifier.emailLow, L: lcklow@hkucc.hku.hken_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.identifier.authorityLow, L=rp00337en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/00006454-199809001-00014en_HK
dc.identifier.pmid9781752-
dc.identifier.scopuseid_2-s2.0-0041339844en_HK
dc.identifier.hkuros38768en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0041339844&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume17en_HK
dc.identifier.issue9 SUPPL.en_HK
dc.identifier.spageS165en_HK
dc.identifier.epageS169en_HK
dc.identifier.isiWOS:000076325400014-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK
dc.identifier.scopusauthoridYung, R=7005594277en_HK
dc.identifier.scopusauthoridLow, L=7007049461en_HK
dc.identifier.scopusauthoridSung, R=7101684314en_HK
dc.identifier.scopusauthoridLeung, CW=7402612619en_HK
dc.identifier.scopusauthoridLee, WH=7407087754en_HK

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