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Article: Review of IgG subclass and IgA deficiency in a tertiary center

TitleReview of IgG subclass and IgA deficiency in a tertiary center
Authors
KeywordsChinese
IgA deficiency
IgG subclass deficiency
Issue Date2006
PublisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.asp
Citation
Hong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 205-209+264 How to Cite?
AbstractWe retrospectively reviewed the clinical characteristics of twenty patients with IgA and/or IgG subclass deficiency attending a tertiary centre. The median age at diagnosis was 1.21 years and the median duration of follow up was 3.83 years. The most common presenting symptom was recurrent sinopulmonary infections (45%). This was followed by refractory asthma (30%), autoimmunity (15%), and other atopic manifestations (10%). Only one out of twenty patients presented with chronic gastrointestinal disease, which contrasted with the majority of previous literature. Three patients had significant pulmonary complications including bronchiolitis obliterans, bronchiectasis and pulmonary fibrosis. The prevalence of IgA deficiency in Hong Kong Chinese population is yet to be established, though it appears not as prevalent as that in western population.
Persistent Identifierhttp://hdl.handle.net/10722/79969
ISSN
2014 Impact Factor: 0.133
2013 SCImago Journal Rankings: 0.126
References

 

DC FieldValueLanguage
dc.contributor.authorChong, CYen_HK
dc.contributor.authorLee, TLen_HK
dc.contributor.authorHo, MHKen_HK
dc.contributor.authorLee, SLen_HK
dc.contributor.authorLau, YLen_HK
dc.date.accessioned2010-09-06T08:00:52Z-
dc.date.available2010-09-06T08:00:52Z-
dc.date.issued2006en_HK
dc.identifier.citationHong Kong Journal Of Paediatrics, 2006, v. 11 n. 3, p. 205-209+264en_HK
dc.identifier.issn1013-9923en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79969-
dc.description.abstractWe retrospectively reviewed the clinical characteristics of twenty patients with IgA and/or IgG subclass deficiency attending a tertiary centre. The median age at diagnosis was 1.21 years and the median duration of follow up was 3.83 years. The most common presenting symptom was recurrent sinopulmonary infections (45%). This was followed by refractory asthma (30%), autoimmunity (15%), and other atopic manifestations (10%). Only one out of twenty patients presented with chronic gastrointestinal disease, which contrasted with the majority of previous literature. Three patients had significant pulmonary complications including bronchiolitis obliterans, bronchiectasis and pulmonary fibrosis. The prevalence of IgA deficiency in Hong Kong Chinese population is yet to be established, though it appears not as prevalent as that in western population.en_HK
dc.languageengen_HK
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkjpaed.org/index.aspen_HK
dc.relation.ispartofHong Kong Journal of Paediatricsen_HK
dc.subjectChineseen_HK
dc.subjectIgA deficiencyen_HK
dc.subjectIgG subclass deficiencyen_HK
dc.titleReview of IgG subclass and IgA deficiency in a tertiary centeren_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1013-9923&volume=11&spage=205&epage=209&date=2006&atitle=Review+of+IgG+subclass+and+IgA+deficiency+in+a+tertiary+centeren_HK
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-33746337597en_HK
dc.identifier.hkuros120579en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33746337597&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume11en_HK
dc.identifier.issue3en_HK
dc.identifier.spage205en_HK
dc.identifier.epage209+264en_HK
dc.publisher.placeHong Kongen_HK
dc.identifier.scopusauthoridChong, CY=14047923000en_HK
dc.identifier.scopusauthoridLee, TL=24483772800en_HK
dc.identifier.scopusauthoridHo, MHK=36554116300en_HK
dc.identifier.scopusauthoridLee, SL=8708381600en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK

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