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Article: Parametric modelling of neonatal mortality in relation to size at birth

TitleParametric modelling of neonatal mortality in relation to size at birth
Authors
Issue Date2001
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-6715/
Citation
Statistics In Medicine, 2001, v. 20 n. 16, p. 2455-2466 How to Cite?
AbstractWe use a richly parameterized model to analyse the effects of shortness and thinness at birth on neonatal mortality in Swedish live-born singletons. The model captures the hazard of neonatal mortality according to the function α × exp(-γ × t) + δ, where t represents age. Covariates are allowed to simultaneously influence the initial excess hazard, the rate of decay, and the long-term hazard. Among term newborns, birth length for gestational age had a stronger effect on the long-term hazard and a weaker effect on the initial excess hazard than the Ponderal index. The initial excess hazard associated with a low Ponderal index tended to decay quickly. Among preterm newborns, a higher birth length for gestational age was associated with lower initial and long-term hazards, and with a faster rate of decay of the initial excess hazard. In contrast, the Ponderal index was not associated with the long-term hazard. We discuss the interpretability of the model and its potential use in neonatology and medical demography. We also compare the model to a Cox model with time-dependent covariates. Copyright © 2001 John Wiley & Sons, Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/79785
ISSN
2015 Impact Factor: 1.533
2015 SCImago Journal Rankings: 1.811
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheung, YBen_HK
dc.contributor.authorYip, PSFen_HK
dc.contributor.authorKarlberg, JPEen_HK
dc.date.accessioned2010-09-06T07:58:42Z-
dc.date.available2010-09-06T07:58:42Z-
dc.date.issued2001en_HK
dc.identifier.citationStatistics In Medicine, 2001, v. 20 n. 16, p. 2455-2466en_HK
dc.identifier.issn0277-6715en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79785-
dc.description.abstractWe use a richly parameterized model to analyse the effects of shortness and thinness at birth on neonatal mortality in Swedish live-born singletons. The model captures the hazard of neonatal mortality according to the function α × exp(-γ × t) + δ, where t represents age. Covariates are allowed to simultaneously influence the initial excess hazard, the rate of decay, and the long-term hazard. Among term newborns, birth length for gestational age had a stronger effect on the long-term hazard and a weaker effect on the initial excess hazard than the Ponderal index. The initial excess hazard associated with a low Ponderal index tended to decay quickly. Among preterm newborns, a higher birth length for gestational age was associated with lower initial and long-term hazards, and with a faster rate of decay of the initial excess hazard. In contrast, the Ponderal index was not associated with the long-term hazard. We discuss the interpretability of the model and its potential use in neonatology and medical demography. We also compare the model to a Cox model with time-dependent covariates. Copyright © 2001 John Wiley & Sons, Ltd.en_HK
dc.languageengen_HK
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www.interscience.wiley.com/jpages/0277-6715/en_HK
dc.relation.ispartofStatistics in Medicineen_HK
dc.rightsStatistics in Medicine. Copyright © John Wiley & Sons Ltd.en_HK
dc.titleParametric modelling of neonatal mortality in relation to size at birthen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0277-6715&volume=20&spage=2455&epage=2466&date=2001&atitle=Parametric+modelling+of+neonatal+mortality+in+relation+to+size+at+birthen_HK
dc.identifier.emailYip, PSF: sfpyip@hku.hken_HK
dc.identifier.emailKarlberg, JPE: jpekarl@hkucc.hku.hken_HK
dc.identifier.authorityYip, PSF=rp00596en_HK
dc.identifier.authorityKarlberg, JPE=rp00400en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1002/sim.858en_HK
dc.identifier.pmid11512135-
dc.identifier.scopuseid_2-s2.0-0035974933en_HK
dc.identifier.hkuros65470en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035974933&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume20en_HK
dc.identifier.issue16en_HK
dc.identifier.spage2455en_HK
dc.identifier.epage2466en_HK
dc.identifier.isiWOS:000170551400007-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridCheung, YB=7202111441en_HK
dc.identifier.scopusauthoridYip, PSF=7102503720en_HK
dc.identifier.scopusauthoridKarlberg, JPE=7005218406en_HK

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