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Article: Effect of sevoflurane/nitrous oxide versus propofol anaesthesia on somatosensory evoked potential monitoring of the spinal cord during surgery to correct scoliosis

TitleEffect of sevoflurane/nitrous oxide versus propofol anaesthesia on somatosensory evoked potential monitoring of the spinal cord during surgery to correct scoliosis
Authors
KeywordsAnaesthetics i.v., propofol
Anaesthetics volatile, sevoflurane
Monitoring, somatosensory evoked potential
Surgery, spinal
Issue Date2002
PublisherOxford University Press. The Journal's web site is located at http://bja.oxfordjournals.org/
Citation
British Journal Of Anaesthesia, 2002, v. 88 n. 4, p. 502-507 How to Cite?
AbstractBackground. Use of intraoperative somatosensory evoked potential (SSEP) monitoring is helpful in spinal corrective surgery but may be affected by anaesthetic drugs. An anaesthetic technique that has less effect on SSEP or allows faster recovery is an advantage. We compared the effects on SSEP and the clinical recovery profiles of sevoflurane/nitrous oxide and propofol anaesthesia during surgery to correct scoliosis. Methods. Twenty adolescent patients were randomized into two groups of 10. One group received sevoflurane-nitrous oxide anaesthesia and the other received propofol i.v. anaesthesia. An alfentanil infusion was used for analgesia in both groups. Results. Changes in anaesthetic concentration produced little effect on the latency of SSEP, but the effect on the variability of SSEP amplitude was significant (P<0.05). Sevoflurane produced a faster decrease in SSEP and a faster recovery than propofol (P<0.05). On emergence, patients who received sevoflurane tended to have shorter recovery times to eye opening (mean 5.1 vs 20.6 min, P=0.09) and toe movement (mean 7.9 vs 15.7 min, P=0.22). Those who had received sevoflurane were significantly more lucid and cooperative in recovery. Conclusions. Sevoflurane produces a faster decrease and recovery of SSEP amplitude as well as a better conscious state on emergence than propofol.
Persistent Identifierhttp://hdl.handle.net/10722/79705
ISSN
2015 Impact Factor: 5.616
2015 SCImago Journal Rankings: 2.314
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorKu, ASWen_HK
dc.contributor.authorHu, Yen_HK
dc.contributor.authorIrwin, MGen_HK
dc.contributor.authorChow, Ben_HK
dc.contributor.authorGunawardene, Sen_HK
dc.contributor.authorTan, EEen_HK
dc.contributor.authorLuk, KDKen_HK
dc.date.accessioned2010-09-06T07:57:39Z-
dc.date.available2010-09-06T07:57:39Z-
dc.date.issued2002en_HK
dc.identifier.citationBritish Journal Of Anaesthesia, 2002, v. 88 n. 4, p. 502-507en_HK
dc.identifier.issn0007-0912en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79705-
dc.description.abstractBackground. Use of intraoperative somatosensory evoked potential (SSEP) monitoring is helpful in spinal corrective surgery but may be affected by anaesthetic drugs. An anaesthetic technique that has less effect on SSEP or allows faster recovery is an advantage. We compared the effects on SSEP and the clinical recovery profiles of sevoflurane/nitrous oxide and propofol anaesthesia during surgery to correct scoliosis. Methods. Twenty adolescent patients were randomized into two groups of 10. One group received sevoflurane-nitrous oxide anaesthesia and the other received propofol i.v. anaesthesia. An alfentanil infusion was used for analgesia in both groups. Results. Changes in anaesthetic concentration produced little effect on the latency of SSEP, but the effect on the variability of SSEP amplitude was significant (P<0.05). Sevoflurane produced a faster decrease in SSEP and a faster recovery than propofol (P<0.05). On emergence, patients who received sevoflurane tended to have shorter recovery times to eye opening (mean 5.1 vs 20.6 min, P=0.09) and toe movement (mean 7.9 vs 15.7 min, P=0.22). Those who had received sevoflurane were significantly more lucid and cooperative in recovery. Conclusions. Sevoflurane produces a faster decrease and recovery of SSEP amplitude as well as a better conscious state on emergence than propofol.en_HK
dc.languageengen_HK
dc.publisherOxford University Press. The Journal's web site is located at http://bja.oxfordjournals.org/en_HK
dc.relation.ispartofBritish Journal of Anaesthesiaen_HK
dc.rightsBritish Journal of Anaesthesia. Copyright © Oxford University Press.en_HK
dc.subjectAnaesthetics i.v., propofolen_HK
dc.subjectAnaesthetics volatile, sevofluraneen_HK
dc.subjectMonitoring, somatosensory evoked potentialen_HK
dc.subjectSurgery, spinalen_HK
dc.subject.meshAnesthetics, Inhalation - pharmacology-
dc.subject.meshAnesthetics, Intravenous - pharmacology-
dc.subject.meshEvoked Potentials, Somatosensory - drug effects-
dc.subject.meshMonitoring, Intraoperative - methods-
dc.subject.meshScoliosis - surgery-
dc.titleEffect of sevoflurane/nitrous oxide versus propofol anaesthesia on somatosensory evoked potential monitoring of the spinal cord during surgery to correct scoliosisen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0007-0912&volume=88&spage=502&epage=507&date=2002&atitle=The+effect+of+sevoflurane/nitrous+oxide+versus+propofol+anaesthesia+on+somatosensory+evoked+potential+monitoring+of+the+spinal+cord+during+scoliosis+corrective+surgeryen_HK
dc.identifier.emailHu, Y:yhud@hku.hken_HK
dc.identifier.emailIrwin, MG:mgirwin@hku.hken_HK
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.identifier.authorityIrwin, MG=rp00390en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1093/bja/88.4.502en_HK
dc.identifier.pmid12066725-
dc.identifier.scopuseid_2-s2.0-0036208221en_HK
dc.identifier.hkuros117044en_HK
dc.identifier.hkuros67248en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036208221&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume88en_HK
dc.identifier.issue4en_HK
dc.identifier.spage502en_HK
dc.identifier.epage507en_HK
dc.identifier.isiWOS:000174851700008-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridKu, ASW=7005556372en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK
dc.identifier.scopusauthoridIrwin, MG=7202411076en_HK
dc.identifier.scopusauthoridChow, B=36338944000en_HK
dc.identifier.scopusauthoridGunawardene, S=55310184300en_HK
dc.identifier.scopusauthoridTan, EE=19036418400en_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK

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