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Article: In vitro bioactivity and osteoblast response on chemically modified biomedical porous NiTi synthesized by capsule-free hot isostatic pressing

TitleIn vitro bioactivity and osteoblast response on chemically modified biomedical porous NiTi synthesized by capsule-free hot isostatic pressing
Authors
KeywordsApatite
Bioactivity
Chemical modification
Hot isostatic pressing
Porous NiTi
Shape memory alloy
Issue Date2008
PublisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/surfcoat
Citation
Surface And Coatings Technology, 2008, v. 202 n. 11, p. 2458-2462 How to Cite?
AbstractPorous biomedical NiTi with an average porosity of 56% and a general pore size of 50-800 μm was synthesized by capsule-free hot isostatic pressing (CF-HIP) with NH4HCO3 as a space holder. In order to enhance the surface bioactivity, the porous alloy was subjected to H2O2 to form a TiO2 coating followed by a NaOH treatment. Scanning electron microscopy (SEM), thin film X-ray diffraction (TF-XRD), and X-ray photoelectron spectroscopy (XPS) revealed that a porous sodium titanate (Na2TiO3) film formed on the surface of the porous NiTi due to the chemical reaction between NaOH and pre-formed TiO2 at the interface between the NaOH solution and porous NiTi. An apatite layer was formed on the film after immersion in simulated body fluids (SBF) at 37 °C while no apatite could be found on the surface of the untreated porous NiTi. Formation of the apatite layer indicates that the chemically treated porous NiTi possesses excellent bioactivity and this bodes well for applications in bone implants. In our preliminary cell culture tests, osteoblast cells were found to attach and proliferate better on the chemically treated samples compared to the untreated alloys. © 2007 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/79603
ISSN
2015 Impact Factor: 2.139
2015 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWu, Sen_HK
dc.contributor.authorLiu, Xen_HK
dc.contributor.authorChan, YLen_HK
dc.contributor.authorChung, CYen_HK
dc.contributor.authorChu, PKen_HK
dc.contributor.authorChu, CLen_HK
dc.contributor.authorLam, KOen_HK
dc.contributor.authorYeung, KWKen_HK
dc.contributor.authorLu, WWen_HK
dc.contributor.authorLuk, KDKen_HK
dc.contributor.authorCheung, KMCen_HK
dc.date.accessioned2010-09-06T07:56:31Z-
dc.date.available2010-09-06T07:56:31Z-
dc.date.issued2008en_HK
dc.identifier.citationSurface And Coatings Technology, 2008, v. 202 n. 11, p. 2458-2462en_HK
dc.identifier.issn0257-8972en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79603-
dc.description.abstractPorous biomedical NiTi with an average porosity of 56% and a general pore size of 50-800 μm was synthesized by capsule-free hot isostatic pressing (CF-HIP) with NH4HCO3 as a space holder. In order to enhance the surface bioactivity, the porous alloy was subjected to H2O2 to form a TiO2 coating followed by a NaOH treatment. Scanning electron microscopy (SEM), thin film X-ray diffraction (TF-XRD), and X-ray photoelectron spectroscopy (XPS) revealed that a porous sodium titanate (Na2TiO3) film formed on the surface of the porous NiTi due to the chemical reaction between NaOH and pre-formed TiO2 at the interface between the NaOH solution and porous NiTi. An apatite layer was formed on the film after immersion in simulated body fluids (SBF) at 37 °C while no apatite could be found on the surface of the untreated porous NiTi. Formation of the apatite layer indicates that the chemically treated porous NiTi possesses excellent bioactivity and this bodes well for applications in bone implants. In our preliminary cell culture tests, osteoblast cells were found to attach and proliferate better on the chemically treated samples compared to the untreated alloys. © 2007 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier SA. The Journal's web site is located at http://www.elsevier.com/locate/surfcoaten_HK
dc.relation.ispartofSurface and Coatings Technologyen_HK
dc.subjectApatiteen_HK
dc.subjectBioactivityen_HK
dc.subjectChemical modificationen_HK
dc.subjectHot isostatic pressingen_HK
dc.subjectPorous NiTien_HK
dc.subjectShape memory alloyen_HK
dc.titleIn vitro bioactivity and osteoblast response on chemically modified biomedical porous NiTi synthesized by capsule-free hot isostatic pressingen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0257-8972&volume=202&spage=2458&epage=2462&date=2008&atitle=In+vitro+bioactivity+and+osteoblast+response+on+chemically+modified+biomedical+porous+NiTi+synthesized+by+capsule-free+hot+isostatic+pressingen_HK
dc.identifier.emailYeung, KWK:wkkyeung@hkucc.hku.hken_HK
dc.identifier.emailLu, WW:wwlu@hku.hken_HK
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_HK
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_HK
dc.identifier.authorityYeung, KWK=rp00309en_HK
dc.identifier.authorityLu, WW=rp00411en_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.authorityCheung, KMC=rp00387en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.surfcoat.2007.08.054en_HK
dc.identifier.scopuseid_2-s2.0-38949132582en_HK
dc.identifier.hkuros145984en_HK
dc.identifier.hkuros166286-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38949132582&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume202en_HK
dc.identifier.issue11en_HK
dc.identifier.spage2458en_HK
dc.identifier.epage2462en_HK
dc.identifier.isiWOS:000253930900047-
dc.publisher.placeSwitzerlanden_HK
dc.identifier.scopusauthoridWu, S=15125218800en_HK
dc.identifier.scopusauthoridLiu, X=8408205200en_HK
dc.identifier.scopusauthoridChan, YL=8250546500en_HK
dc.identifier.scopusauthoridChung, CY=8100842800en_HK
dc.identifier.scopusauthoridChu, PK=36040705700en_HK
dc.identifier.scopusauthoridChu, CL=7404345713en_HK
dc.identifier.scopusauthoridLam, KO=22980533000en_HK
dc.identifier.scopusauthoridYeung, KWK=13309584700en_HK
dc.identifier.scopusauthoridLu, WW=7404215221en_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK
dc.identifier.scopusauthoridCheung, KMC=7402406754en_HK

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