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Article: Effect of segmental artery ligation on the blood supply of the thoracic spinal cord during anterior spinal surgery: A quantitative histomorphological fresh cadaver study

TitleEffect of segmental artery ligation on the blood supply of the thoracic spinal cord during anterior spinal surgery: A quantitative histomorphological fresh cadaver study
Authors
KeywordsBlood supply
Ligation
Segmental artery
Spinal cord
Issue Date2005
PublisherLippincott, Williams & Wilkins. The Journal's web site is located at http://www.spinejournal.com
Citation
Spine, 2005, v. 30 n. 5, p. 483-486 How to Cite?
AbstractStudy Design. Human cadaver quantitative morphometric analysis of the blood vessels in the spinal cord after ligation of segmental arteries. Objectives. To investigate the effect of ligation of segmental arteries on the quantity and density of the blood vessels in the spinal cord. Summary of Background Data. Ligation of segmental arteries is often used in the anterior approach for correction scoliosis. However, whether or not segmental artery ligation is liable to deny the spinal cord an adequate blood supply, thus leading to paraplegia, still remains controversial. Methods. Eleven fresh cadavers were divided into control, unilateral, and bilateral groups. For the unilateral and bilateral groups, 5 segmental vertebral arteries (T7-T11) were ligated unilaterally and bilaterally, respectively. Then, the number and density of blood vessels at different levels in the 3 groups were measured. Results. Compared to that of the corresponding level in the control group, the number of blood vessels at T5 to L1 all decreased in the ligation groups. And significant differences were found at T8 (82.80 ± 16.36), T10 (77.80 ± 19.80), and T11 (99.20 ± 14.85) levels, compared to those of the corresponding levels in the control group: T8 (175.80 ± 8. 31), T9 (176.40 ± 32. 33), T10 (171.40 ± 9. 73), and T11 (189.20 ± 15. 92). Further decrease was found at each corresponding level in the bilateral group, and significant differences were found at T8 (65.80 ± 15.55), T9 (24.80 ± 13.43), T10 (0), T11 (0), and T12 (0) levels. Similar results were obtained with regard to the density of blood vessels. Significant differences were found at T11 (1.246 ± 0.112) and L1 (1.349 ± 0.109) in the unilateral group, and T9 (0.260 ± 0.088), T10 (0), T11 (0), T12 (0), and L1 (0.147 ± 0.117) in the bilateral group compared to those of the corresponding levels in the control group: T9 (1.810 ± 0.202), T10 (1.833 ± 0.175), T11 (2.308 ± 0.335), T12 (2.510 ± 0.617), and L1 (2.193 ± 0.033). Conclusions. This study suggests that the more levels the ligation encompasses, the higher the risk of spinal cord damage. Therefore, caution should be taken when several segmental arteries are to be ligated in the clinical setting. What is more, bilateral ligation, which is worse than unilateral ligation, can lead to a significant decrease in the number and density of blood vessels of the spinal. © 2005, Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/79450
ISSN
2015 Impact Factor: 2.439
2015 SCImago Journal Rankings: 1.459
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYuan, Len_HK
dc.contributor.authorNi, GXen_HK
dc.contributor.authorLuk, KDKen_HK
dc.contributor.authorCheung, KMCen_HK
dc.contributor.authorLu, DSen_HK
dc.contributor.authorHu, Yen_HK
dc.contributor.authorDai, JXen_HK
dc.contributor.authorWong, YWen_HK
dc.contributor.authorLu, WWen_HK
dc.date.accessioned2010-09-06T07:54:49Z-
dc.date.available2010-09-06T07:54:49Z-
dc.date.issued2005en_HK
dc.identifier.citationSpine, 2005, v. 30 n. 5, p. 483-486en_HK
dc.identifier.issn0362-2436en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79450-
dc.description.abstractStudy Design. Human cadaver quantitative morphometric analysis of the blood vessels in the spinal cord after ligation of segmental arteries. Objectives. To investigate the effect of ligation of segmental arteries on the quantity and density of the blood vessels in the spinal cord. Summary of Background Data. Ligation of segmental arteries is often used in the anterior approach for correction scoliosis. However, whether or not segmental artery ligation is liable to deny the spinal cord an adequate blood supply, thus leading to paraplegia, still remains controversial. Methods. Eleven fresh cadavers were divided into control, unilateral, and bilateral groups. For the unilateral and bilateral groups, 5 segmental vertebral arteries (T7-T11) were ligated unilaterally and bilaterally, respectively. Then, the number and density of blood vessels at different levels in the 3 groups were measured. Results. Compared to that of the corresponding level in the control group, the number of blood vessels at T5 to L1 all decreased in the ligation groups. And significant differences were found at T8 (82.80 ± 16.36), T10 (77.80 ± 19.80), and T11 (99.20 ± 14.85) levels, compared to those of the corresponding levels in the control group: T8 (175.80 ± 8. 31), T9 (176.40 ± 32. 33), T10 (171.40 ± 9. 73), and T11 (189.20 ± 15. 92). Further decrease was found at each corresponding level in the bilateral group, and significant differences were found at T8 (65.80 ± 15.55), T9 (24.80 ± 13.43), T10 (0), T11 (0), and T12 (0) levels. Similar results were obtained with regard to the density of blood vessels. Significant differences were found at T11 (1.246 ± 0.112) and L1 (1.349 ± 0.109) in the unilateral group, and T9 (0.260 ± 0.088), T10 (0), T11 (0), T12 (0), and L1 (0.147 ± 0.117) in the bilateral group compared to those of the corresponding levels in the control group: T9 (1.810 ± 0.202), T10 (1.833 ± 0.175), T11 (2.308 ± 0.335), T12 (2.510 ± 0.617), and L1 (2.193 ± 0.033). Conclusions. This study suggests that the more levels the ligation encompasses, the higher the risk of spinal cord damage. Therefore, caution should be taken when several segmental arteries are to be ligated in the clinical setting. What is more, bilateral ligation, which is worse than unilateral ligation, can lead to a significant decrease in the number and density of blood vessels of the spinal. © 2005, Lippincott Williams & Wilkins, Inc.en_HK
dc.languageengen_HK
dc.publisherLippincott, Williams & Wilkins. The Journal's web site is located at http://www.spinejournal.comen_HK
dc.relation.ispartofSpineen_HK
dc.subjectBlood supplyen_HK
dc.subjectLigationen_HK
dc.subjectSegmental arteryen_HK
dc.subjectSpinal corden_HK
dc.titleEffect of segmental artery ligation on the blood supply of the thoracic spinal cord during anterior spinal surgery: A quantitative histomorphological fresh cadaver studyen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0887-9869&volume=30&issue=5&spage=483&epage=486&date=2005&atitle=Effect+of+segmental+artery+ligation+on+the+blood+supply+of+the+thoracic+spinal+cord+during+anterior+spinal+surgery:+a+quantitative+histomorphological+fresh+cadaver+studyen_HK
dc.identifier.emailLuk, KDK:hcm21000@hku.hken_HK
dc.identifier.emailCheung, KMC:cheungmc@hku.hken_HK
dc.identifier.emailHu, Y:yhud@hku.hken_HK
dc.identifier.emailLu, WW:wwlu@hku.hken_HK
dc.identifier.authorityLuk, KDK=rp00333en_HK
dc.identifier.authorityCheung, KMC=rp00387en_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.identifier.authorityLu, WW=rp00411en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/01.brs.0000154622.49240.ffen_HK
dc.identifier.pmid15738778en_HK
dc.identifier.scopuseid_2-s2.0-14344264327en_HK
dc.identifier.hkuros101718en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-14344264327&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume30en_HK
dc.identifier.issue5en_HK
dc.identifier.spage483en_HK
dc.identifier.epage486en_HK
dc.identifier.isiWOS:000227323000001-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYuan, L=7402011253en_HK
dc.identifier.scopusauthoridNi, GX=8303037400en_HK
dc.identifier.scopusauthoridLuk, KDK=7201921573en_HK
dc.identifier.scopusauthoridCheung, KMC=7402406754en_HK
dc.identifier.scopusauthoridLu, DS=7403079533en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK
dc.identifier.scopusauthoridDai, JX=7401679121en_HK
dc.identifier.scopusauthoridWong, YW=36247941700en_HK
dc.identifier.scopusauthoridLu, WW=7404215221en_HK

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