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Article: Theoretical modeling study of the necrotic field during high-intensity focused ultrasound surgery

TitleTheoretical modeling study of the necrotic field during high-intensity focused ultrasound surgery
Authors
KeywordsCellular thermo-necrotic theory
High-Intensity Focused Ultrasound (HIFU)
Necrotic field
Non-interferential
Self-focused system with multi-transducers
Issue Date2004
PublisherMedical Science International Publishing. The Journal's web site is located at http://www.medscimonit.com
Citation
Medical Science Monitor, 2004, v. 10 n. 2, p. MT19-MT23 How to Cite?
AbstractBackground: High-intensity focused ultrasound (HIFU) is a type of micro-invasive treatment of tumor. It is important to create a guideline for the volume and position of the necrotic field by means of a theoretical model, this being one of the key problems in the clinic application of HIFU. Material/Methods: Based on cellular thermo-necrotic theory, a computational model of temperature distribution and, therefore, the necrotic field was developed. A multi-transducer system with non-interferential and self-focused property was devised to provide experimental verification of the theoretical model. Results: The necrotic field resulting from the modeling simulation did not show any evident difference from that of the experiment. The necrotic field of the same heating duration (4 seconds) was found with both modeling and experiment to be spheroid, with its center at the system's geometric focus and a volume of 1x1x2 cm3. Conclusions: The model of this study may predict the practical volume of the necrotic field as well as the time needed for it to form.
Persistent Identifierhttp://hdl.handle.net/10722/79334
ISSN
2012 Impact Factor: 1.358
2015 SCImago Journal Rankings: 0.512
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMing, Den_HK
dc.contributor.authorWan, BKen_HK
dc.contributor.authorZhang, LXen_HK
dc.contributor.authorHu, Yen_HK
dc.date.accessioned2010-09-06T07:53:30Z-
dc.date.available2010-09-06T07:53:30Z-
dc.date.issued2004en_HK
dc.identifier.citationMedical Science Monitor, 2004, v. 10 n. 2, p. MT19-MT23en_HK
dc.identifier.issn1234-1010en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79334-
dc.description.abstractBackground: High-intensity focused ultrasound (HIFU) is a type of micro-invasive treatment of tumor. It is important to create a guideline for the volume and position of the necrotic field by means of a theoretical model, this being one of the key problems in the clinic application of HIFU. Material/Methods: Based on cellular thermo-necrotic theory, a computational model of temperature distribution and, therefore, the necrotic field was developed. A multi-transducer system with non-interferential and self-focused property was devised to provide experimental verification of the theoretical model. Results: The necrotic field resulting from the modeling simulation did not show any evident difference from that of the experiment. The necrotic field of the same heating duration (4 seconds) was found with both modeling and experiment to be spheroid, with its center at the system's geometric focus and a volume of 1x1x2 cm3. Conclusions: The model of this study may predict the practical volume of the necrotic field as well as the time needed for it to form.en_HK
dc.languageengen_HK
dc.publisherMedical Science International Publishing. The Journal's web site is located at http://www.medscimonit.comen_HK
dc.relation.ispartofMedical Science Monitoren_HK
dc.subjectCellular thermo-necrotic theoryen_HK
dc.subjectHigh-Intensity Focused Ultrasound (HIFU)en_HK
dc.subjectNecrotic fielden_HK
dc.subjectNon-interferentialen_HK
dc.subjectSelf-focused system with multi-transducersen_HK
dc.titleTheoretical modeling study of the necrotic field during high-intensity focused ultrasound surgeryen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0269-8951&volume=10&issue=2&spage=MT19&epage=23&date=2004&atitle=Theoretical+modeling+study+of+the+necrotic+field+during+high-intensity+focused+ultrasound+surgeryen_HK
dc.identifier.emailHu, Y:yhud@hku.hken_HK
dc.identifier.authorityHu, Y=rp00432en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid14737051-
dc.identifier.scopuseid_2-s2.0-1242330813en_HK
dc.identifier.hkuros94048en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-1242330813&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume10en_HK
dc.identifier.issue2en_HK
dc.identifier.spageMT19en_HK
dc.identifier.epageMT23en_HK
dc.identifier.isiWOS:000224831400019-
dc.publisher.placePolanden_HK
dc.identifier.scopusauthoridMing, D=9745824400en_HK
dc.identifier.scopusauthoridWan, BK=7102316798en_HK
dc.identifier.scopusauthoridZhang, LX=9740344900en_HK
dc.identifier.scopusauthoridHu, Y=7407116091en_HK

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