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- Publisher Website: 10.1126/science.1087139
- Scopus: eid_2-s2.0-0141889936
- PMID: 12958366
- WOS: WOS:000185825900039
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Article: Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China
Title | Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China |
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Authors | |
Issue Date | 2003 |
Publisher | American Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org |
Citation | Science, 2003, v. 302 n. 5643, p. 276-278 How to Cite? |
Abstract | A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known. |
Persistent Identifier | http://hdl.handle.net/10722/79280 |
ISSN | 2023 Impact Factor: 44.7 2023 SCImago Journal Rankings: 11.902 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Guan, Y | en_HK |
dc.contributor.author | Zheng, BJ | en_HK |
dc.contributor.author | He, YQ | en_HK |
dc.contributor.author | Liu, XL | en_HK |
dc.contributor.author | Zhuang, ZX | en_HK |
dc.contributor.author | Cheung, CL | en_HK |
dc.contributor.author | Luo, SW | en_HK |
dc.contributor.author | Li, PH | en_HK |
dc.contributor.author | Zhang, LJ | en_HK |
dc.contributor.author | Guan, YJ | en_HK |
dc.contributor.author | Butt, KM | en_HK |
dc.contributor.author | Wong, KL | en_HK |
dc.contributor.author | Chan, KW | en_HK |
dc.contributor.author | Lim, W | en_HK |
dc.contributor.author | Shortridge, KF | en_HK |
dc.contributor.author | Yuen, KY | en_HK |
dc.contributor.author | Peiris, JSM | en_HK |
dc.contributor.author | Poon, LLM | en_HK |
dc.date.accessioned | 2010-09-06T07:52:46Z | - |
dc.date.available | 2010-09-06T07:52:46Z | - |
dc.date.issued | 2003 | en_HK |
dc.identifier.citation | Science, 2003, v. 302 n. 5643, p. 276-278 | en_HK |
dc.identifier.issn | 0036-8075 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/79280 | - |
dc.description.abstract | A novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known. | en_HK |
dc.language | eng | en_HK |
dc.publisher | American Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org | en_HK |
dc.relation.ispartof | Science | en_HK |
dc.rights | Science. Copyright © American Association for the Advancement of Science. | en_HK |
dc.subject.mesh | Amino Acid Sequence | en_HK |
dc.subject.mesh | Animals | en_HK |
dc.subject.mesh | Animals, Wild - virology | en_HK |
dc.subject.mesh | Antibodies, Viral - blood | en_HK |
dc.subject.mesh | Blotting, Western | en_HK |
dc.subject.mesh | Carnivora - virology | en_HK |
dc.subject.mesh | China | en_HK |
dc.subject.mesh | Coronavirus - classification - genetics - immunology - isolation & purification | en_HK |
dc.subject.mesh | Coronavirus Infections - veterinary - virology | en_HK |
dc.subject.mesh | Disease Reservoirs | en_HK |
dc.subject.mesh | Feces - virology | en_HK |
dc.subject.mesh | Genome, Viral | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Membrane Glycoproteins - chemistry - genetics | en_HK |
dc.subject.mesh | Molecular Sequence Data | en_HK |
dc.subject.mesh | Neutralization Tests | en_HK |
dc.subject.mesh | Nose - virology | en_HK |
dc.subject.mesh | Open Reading Frames - genetics | en_HK |
dc.subject.mesh | Phylogeny | en_HK |
dc.subject.mesh | Polymorphism, Genetic | en_HK |
dc.subject.mesh | Reverse Transcriptase Polymerase Chain Reaction | en_HK |
dc.subject.mesh | SARS Virus - classification - genetics - immunology - isolation & purification | en_HK |
dc.subject.mesh | Sequence Deletion | en_HK |
dc.subject.mesh | Sequence Homology, Nucleic Acid | en_HK |
dc.subject.mesh | Viral Envelope Proteins - chemistry - genetics | en_HK |
dc.subject.mesh | Viral Proteins - chemistry - genetics | en_HK |
dc.title | Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0036-8075&volume=302&issue=5643&spage=276&epage=278&date=2003&atitle=Isolation+and+characterization+of+viruses+related+to+the+SARS+Coronavirus+from+Animals+in+Southern+China. | en_HK |
dc.identifier.email | Guan, Y: yguan@hkucc.hku.hk | en_HK |
dc.identifier.email | Zheng, BJ: bzheng@hkucc.hku.hk | en_HK |
dc.identifier.email | Chan, KW: hrmtckw@hku.hk | en_HK |
dc.identifier.email | Yuen, KY: kyyuen@hkucc.hku.hk | en_HK |
dc.identifier.email | Peiris, JSM: malik@hkucc.hku.hk | en_HK |
dc.identifier.email | Poon, LLM: llmpoon@hkucc.hku.hk | en_HK |
dc.identifier.authority | Guan, Y=rp00397 | en_HK |
dc.identifier.authority | Zheng, BJ=rp00353 | en_HK |
dc.identifier.authority | Chan, KW=rp00330 | en_HK |
dc.identifier.authority | Yuen, KY=rp00366 | en_HK |
dc.identifier.authority | Peiris, JSM=rp00410 | en_HK |
dc.identifier.authority | Poon, LLM=rp00484 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1126/science.1087139 | en_HK |
dc.identifier.pmid | 12958366 | - |
dc.identifier.scopus | eid_2-s2.0-0141889936 | en_HK |
dc.identifier.hkuros | 83082 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0141889936&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 302 | en_HK |
dc.identifier.issue | 5643 | en_HK |
dc.identifier.spage | 276 | en_HK |
dc.identifier.epage | 278 | en_HK |
dc.identifier.isi | WOS:000185825900039 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Guan, Y=7202924055 | en_HK |
dc.identifier.scopusauthorid | Zheng, BJ=7201780588 | en_HK |
dc.identifier.scopusauthorid | He, YQ=35285643800 | en_HK |
dc.identifier.scopusauthorid | Liu, XL=8512397000 | en_HK |
dc.identifier.scopusauthorid | Zhuang, ZX=7203003409 | en_HK |
dc.identifier.scopusauthorid | Cheung, CL=34975244700 | en_HK |
dc.identifier.scopusauthorid | Luo, SW=55254453500 | en_HK |
dc.identifier.scopusauthorid | Li, PH=15127492900 | en_HK |
dc.identifier.scopusauthorid | Zhang, LJ=14046384200 | en_HK |
dc.identifier.scopusauthorid | Guan, YJ=35781153400 | en_HK |
dc.identifier.scopusauthorid | Butt, KM=36061616300 | en_HK |
dc.identifier.scopusauthorid | Wong, KL=7404758889 | en_HK |
dc.identifier.scopusauthorid | Chan, KW=16444133100 | en_HK |
dc.identifier.scopusauthorid | Lim, W=7202378277 | en_HK |
dc.identifier.scopusauthorid | Shortridge, KF=7005677034 | en_HK |
dc.identifier.scopusauthorid | Yuen, KY=36078079100 | en_HK |
dc.identifier.scopusauthorid | Peiris, JSM=7005486823 | en_HK |
dc.identifier.scopusauthorid | Poon, LLM=7005441747 | en_HK |
dc.identifier.issnl | 0036-8075 | - |