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Article: Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China
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TitleIsolation and characterization of viruses related to the SARS coronavirus from animals in Southern China
 
AuthorsGuan, Y2
Zheng, BJ2
He, YQ1
Liu, XL1
Zhuang, ZX1
Cheung, CL2
Luo, SW2
Li, PH2
Zhang, LJ2
Guan, YJ2
Butt, KM2
Wong, KL2
Chan, KW2
Lim, W3
Shortridge, KF2
Yuen, KY2
Peiris, JSM2
Poon, LLM2
 
Issue Date2003
 
PublisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org
 
CitationScience, 2003, v. 302 n. 5643, p. 276-278 [How to Cite?]
DOI: http://dx.doi.org/10.1126/science.1087139
 
AbstractA novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
 
ISSN0036-8075
2013 Impact Factor: 31.477
2013 SCImago Journal Rankings: 12.465
 
DOIhttp://dx.doi.org/10.1126/science.1087139
 
ISI Accession Number IDWOS:000185825900039
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorGuan, Y
 
dc.contributor.authorZheng, BJ
 
dc.contributor.authorHe, YQ
 
dc.contributor.authorLiu, XL
 
dc.contributor.authorZhuang, ZX
 
dc.contributor.authorCheung, CL
 
dc.contributor.authorLuo, SW
 
dc.contributor.authorLi, PH
 
dc.contributor.authorZhang, LJ
 
dc.contributor.authorGuan, YJ
 
dc.contributor.authorButt, KM
 
dc.contributor.authorWong, KL
 
dc.contributor.authorChan, KW
 
dc.contributor.authorLim, W
 
dc.contributor.authorShortridge, KF
 
dc.contributor.authorYuen, KY
 
dc.contributor.authorPeiris, JSM
 
dc.contributor.authorPoon, LLM
 
dc.date.accessioned2010-09-06T07:52:46Z
 
dc.date.available2010-09-06T07:52:46Z
 
dc.date.issued2003
 
dc.description.abstractA novel coronavirus (SCoV) is the etiological agent of severe acute respiratory syndrome (SARS). SCoV-like viruses were isolated from Himalayan palm civets found in a live-animal market in Guangdong, China. Evidence of virus infection was also detected in other animals (including a raccoon dog, Nyctereutes procyonoides) and in humans working at the same market. All the animal isolates retain a 29-nucleotide sequence that is not found in most human isolates. The detection of SCoV-like viruses in small, live wild mammals in a retail market indicates a route of interspecies transmission, although the natural reservoir is not known.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationScience, 2003, v. 302 n. 5643, p. 276-278 [How to Cite?]
DOI: http://dx.doi.org/10.1126/science.1087139
 
dc.identifier.doihttp://dx.doi.org/10.1126/science.1087139
 
dc.identifier.epage278
 
dc.identifier.hkuros83082
 
dc.identifier.isiWOS:000185825900039
 
dc.identifier.issn0036-8075
2013 Impact Factor: 31.477
2013 SCImago Journal Rankings: 12.465
 
dc.identifier.issue5643
 
dc.identifier.openurl
 
dc.identifier.pmid12958366
 
dc.identifier.scopuseid_2-s2.0-0141889936
 
dc.identifier.spage276
 
dc.identifier.urihttp://hdl.handle.net/10722/79280
 
dc.identifier.volume302
 
dc.languageeng
 
dc.publisherAmerican Association for the Advancement of Science. The Journal's web site is located at http://sciencemag.org
 
dc.publisher.placeUnited States
 
dc.relation.ispartofScience
 
dc.relation.referencesReferences in Scopus
 
dc.rightsScience. Copyright © American Association for the Advancement of Science.
 
dc.subject.meshAmino Acid Sequence
 
dc.subject.meshAnimals
 
dc.subject.meshAnimals, Wild - virology
 
dc.subject.meshAntibodies, Viral - blood
 
dc.subject.meshBlotting, Western
 
dc.subject.meshCarnivora - virology
 
dc.subject.meshChina
 
dc.subject.meshCoronavirus - classification - genetics - immunology - isolation & purification
 
dc.subject.meshCoronavirus Infections - veterinary - virology
 
dc.subject.meshDisease Reservoirs
 
dc.subject.meshFeces - virology
 
dc.subject.meshGenome, Viral
 
dc.subject.meshHumans
 
dc.subject.meshMembrane Glycoproteins - chemistry - genetics
 
dc.subject.meshMolecular Sequence Data
 
dc.subject.meshNeutralization Tests
 
dc.subject.meshNose - virology
 
dc.subject.meshOpen Reading Frames - genetics
 
dc.subject.meshPhylogeny
 
dc.subject.meshPolymorphism, Genetic
 
dc.subject.meshReverse Transcriptase Polymerase Chain Reaction
 
dc.subject.meshSARS Virus - classification - genetics - immunology - isolation & purification
 
dc.subject.meshSequence Deletion
 
dc.subject.meshSequence Homology, Nucleic Acid
 
dc.subject.meshViral Envelope Proteins - chemistry - genetics
 
dc.subject.meshViral Proteins - chemistry - genetics
 
dc.titleIsolation and characterization of viruses related to the SARS coronavirus from animals in Southern China
 
dc.typeArticle
 
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Author Affiliations
  1. Shenzhen Center for Disease Control and Prevention
  2. The University of Hong Kong
  3. Government Virus Unit