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Article: One step closer to universal influenza epitopes

TitleOne step closer to universal influenza epitopes
Authors
KeywordsCross-reactive antibody
Hemagglutinin
Influenza
Issue Date2009
PublisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7
Citation
Expert Review Of Anti-Infective Therapy, 2009, v. 7 n. 6, p. 687-690 How to Cite?
AbstractThe continuous antigenic drifts and occasional antigenic shifts enable human influenza viruses to escape the human immune system. Moreover, the frequent occurrence of human H5N1-infected cases and the recent emergency of a novel swine-like human H1N1 influenza virus further reiterate the risk of the introduction of a new pandemic strain to humans through in toto transfer of an animal influenza virus. The discovery of neutralizing antibodies that are broadly reactive with multiple influenza subtypes is therefore extremely important for the influenza pandemic preparedness, for use either for therapeutic purposes or as the basis of vaccine development. Here, we review some of the recent developments in this area. © 2009 Expert Reviews Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/79221
ISSN
2015 Impact Factor: 3.542
2015 SCImago Journal Rankings: 1.415
ISI Accession Number ID
Funding AgencyGrant Number
NIH (NIAID)HHSN266200700005C
HKU Seed Funding Programme for Basic Research200711159027
Area of Excellence Scheme of the University Grants CommitteeAoE/M-12/06
Funding Information:

The authors would like to acknowledge support from the NIH (NIAID contract HHSN266200700005C, Leo LM Poon), HKU Seed Funding Programme for Basic Research (200711159027) and the Area of Excellence Scheme of the University Grants Committee (Grant AoE/M-12/06). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorLi, OTWen_HK
dc.contributor.authorPoon, LLMen_HK
dc.date.accessioned2010-09-06T07:52:03Z-
dc.date.available2010-09-06T07:52:03Z-
dc.date.issued2009en_HK
dc.identifier.citationExpert Review Of Anti-Infective Therapy, 2009, v. 7 n. 6, p. 687-690en_HK
dc.identifier.issn1478-7210en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79221-
dc.description.abstractThe continuous antigenic drifts and occasional antigenic shifts enable human influenza viruses to escape the human immune system. Moreover, the frequent occurrence of human H5N1-infected cases and the recent emergency of a novel swine-like human H1N1 influenza virus further reiterate the risk of the introduction of a new pandemic strain to humans through in toto transfer of an animal influenza virus. The discovery of neutralizing antibodies that are broadly reactive with multiple influenza subtypes is therefore extremely important for the influenza pandemic preparedness, for use either for therapeutic purposes or as the basis of vaccine development. Here, we review some of the recent developments in this area. © 2009 Expert Reviews Ltd.en_HK
dc.languageengen_HK
dc.publisherExpert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7en_HK
dc.relation.ispartofExpert Review of Anti-Infective Therapyen_HK
dc.subjectCross-reactive antibodyen_HK
dc.subjectHemagglutininen_HK
dc.subjectInfluenzaen_HK
dc.titleOne step closer to universal influenza epitopesen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1478-7210&volume=7&spage=687&epage=90&date=2009&atitle=One+step+closer+to+universal+influenza+epitopes.en_HK
dc.identifier.emailPoon, LLM: llmpoon@hkucc.hku.hken_HK
dc.identifier.authorityPoon, LLM=rp00484en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1586/ERI.09.48en_HK
dc.identifier.pmid19681695en_HK
dc.identifier.scopuseid_2-s2.0-70350459697en_HK
dc.identifier.hkuros164350en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-70350459697&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume7en_HK
dc.identifier.issue6en_HK
dc.identifier.spage687en_HK
dc.identifier.epage690en_HK
dc.identifier.isiWOS:000270015300011-
dc.publisher.placeUnited Kingdomen_HK
dc.relation.projectControl of Pandemic and Inter-pandemic Influenza-
dc.identifier.scopusauthoridLi, OTW=36860875900en_HK
dc.identifier.scopusauthoridPoon, LLM=7005441747en_HK

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