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Article: First external quality assurance of antibody diagnostic for SARS-new coronavirus

TitleFirst external quality assurance of antibody diagnostic for SARS-new coronavirus
Authors
KeywordsAntibody diagnostic
EQA
External quality assurance
SARS
Issue Date2005
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jcv
Citation
Journal Of Clinical Virology, 2005, v. 34 n. 1, p. 22-25 How to Cite?
AbstractTo confirm an infection with the new coronavirus (SARS-CoV) causing the severe acute respiratory syndrome (SARS) diagnostic assays for detection of SARS-CoV specific antibody are necessary. To evaluate the diagnostic performance of laboratories an external quality assurance (EQA) study was performed in 2004. Participating laboratories (9/20) correctly detected anti-SARS antibodies in serum samples without false positive results in an immunofluorescence assay. In contrast, only 4/13 laboratories detected most of the anti-SARS antibody positive samples without false positive results using enzyme immunoassays (EIA) and/or immunoblot. The overall results clearly demonstrate that serological diagnosis of SARS-CoV remains at an early stage of development, with further technical improvements required, particularly with respect to the use of SARS specific EIAs. © 2005 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/79140
ISSN
2015 Impact Factor: 2.647
2015 SCImago Journal Rankings: 1.503
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNiedrig, Men_HK
dc.contributor.authorLeitmeyer, Ken_HK
dc.contributor.authorLim, Wen_HK
dc.contributor.authorPeiris, Men_HK
dc.contributor.authorMackenzie, JSen_HK
dc.contributor.authorZambon, Men_HK
dc.date.accessioned2010-09-06T07:51:04Z-
dc.date.available2010-09-06T07:51:04Z-
dc.date.issued2005en_HK
dc.identifier.citationJournal Of Clinical Virology, 2005, v. 34 n. 1, p. 22-25en_HK
dc.identifier.issn1386-6532en_HK
dc.identifier.urihttp://hdl.handle.net/10722/79140-
dc.description.abstractTo confirm an infection with the new coronavirus (SARS-CoV) causing the severe acute respiratory syndrome (SARS) diagnostic assays for detection of SARS-CoV specific antibody are necessary. To evaluate the diagnostic performance of laboratories an external quality assurance (EQA) study was performed in 2004. Participating laboratories (9/20) correctly detected anti-SARS antibodies in serum samples without false positive results in an immunofluorescence assay. In contrast, only 4/13 laboratories detected most of the anti-SARS antibody positive samples without false positive results using enzyme immunoassays (EIA) and/or immunoblot. The overall results clearly demonstrate that serological diagnosis of SARS-CoV remains at an early stage of development, with further technical improvements required, particularly with respect to the use of SARS specific EIAs. © 2005 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/jcven_HK
dc.relation.ispartofJournal of Clinical Virologyen_HK
dc.rightsJournal of Clinical Virology. Copyright © Elsevier BV.en_HK
dc.subjectAntibody diagnosticen_HK
dc.subjectEQAen_HK
dc.subjectExternal quality assuranceen_HK
dc.subjectSARSen_HK
dc.titleFirst external quality assurance of antibody diagnostic for SARS-new coronavirusen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1386-6532&volume=34&issue=1&spage=22&epage=5&date=2005&atitle=First+external+quality+assurance+of+antibody+diagnostic+for+SARS-new+coronavirusen_HK
dc.identifier.emailPeiris, M: malik@hkucc.hku.hken_HK
dc.identifier.authorityPeiris, M=rp00410en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jcv.2005.01.004en_HK
dc.identifier.pmid16087120-
dc.identifier.scopuseid_2-s2.0-23744507266en_HK
dc.identifier.hkuros118127en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-23744507266&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume34en_HK
dc.identifier.issue1en_HK
dc.identifier.spage22en_HK
dc.identifier.epage25en_HK
dc.identifier.isiWOS:000231845300004-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridNiedrig, M=7003827932en_HK
dc.identifier.scopusauthoridLeitmeyer, K=6603438416en_HK
dc.identifier.scopusauthoridLim, W=16205075400en_HK
dc.identifier.scopusauthoridPeiris, M=7005486823en_HK
dc.identifier.scopusauthoridMackenzie, JS=7401614409en_HK
dc.identifier.scopusauthoridZambon, M=7006818684en_HK

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