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Article: H5N1 outbreaks and enzootic influenza

TitleH5N1 outbreaks and enzootic influenza
Authors
Issue Date2006
PublisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm
Citation
Emerging Infectious Diseases, 2006, v. 12 n. 1, p. 3-8 How to Cite?
AbstractOngoing outbreaks of H5N1 avian influenza in migratory waterfowl, domestic poultry, and humans in Asia during the summer of 2005 present a continuing, protean pandemic threat. We review the zoonotic source of highly pathogenic H5N1 viruses and their genesis from their natural reservoirs. The acquisition of novel traits, including lethality to waterfowl, ferrets, felids, and humans, indicates an expanding host range. The natural selection of nonpathogenic viruses from heterogeneous subpopulations cocirculating in ducks contributes to the spread of H5N1 in Asia. Transmission of highly pathogenic H5N1 from domestic poultry back to migratory waterfowl in western China has increased the geographic spread. The spread of H5N1 and its likely reintroduction to domestic poultry increase the need for good agricultural vaccines. In fact, the root cause of the continuing H5N1 pandemic threat may be the way the pathogenicity of H5N1 viruses is masked by cocirculating influenza viruses or bad agricultural vaccines.
Persistent Identifierhttp://hdl.handle.net/10722/78993
ISSN
2015 Impact Factor: 6.994
2015 SCImago Journal Rankings: 3.023
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWebster, RGen_HK
dc.contributor.authorPeiris, Men_HK
dc.contributor.authorChen, Hen_HK
dc.contributor.authorGuan, Yen_HK
dc.date.accessioned2010-09-06T07:49:17Z-
dc.date.available2010-09-06T07:49:17Z-
dc.date.issued2006en_HK
dc.identifier.citationEmerging Infectious Diseases, 2006, v. 12 n. 1, p. 3-8en_HK
dc.identifier.issn1080-6040en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78993-
dc.description.abstractOngoing outbreaks of H5N1 avian influenza in migratory waterfowl, domestic poultry, and humans in Asia during the summer of 2005 present a continuing, protean pandemic threat. We review the zoonotic source of highly pathogenic H5N1 viruses and their genesis from their natural reservoirs. The acquisition of novel traits, including lethality to waterfowl, ferrets, felids, and humans, indicates an expanding host range. The natural selection of nonpathogenic viruses from heterogeneous subpopulations cocirculating in ducks contributes to the spread of H5N1 in Asia. Transmission of highly pathogenic H5N1 from domestic poultry back to migratory waterfowl in western China has increased the geographic spread. The spread of H5N1 and its likely reintroduction to domestic poultry increase the need for good agricultural vaccines. In fact, the root cause of the continuing H5N1 pandemic threat may be the way the pathogenicity of H5N1 viruses is masked by cocirculating influenza viruses or bad agricultural vaccines.en_HK
dc.languageengen_HK
dc.publisherUS Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htmen_HK
dc.relation.ispartofEmerging Infectious Diseasesen_HK
dc.subject.meshAnimal Migrationen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshBirds - physiology - virologyen_HK
dc.subject.meshDisease Outbreaks - prevention & control - veterinaryen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfluenza A Virus, H5N1 Subtype - genetics - immunology - pathogenicity - physiologyen_HK
dc.subject.meshInfluenza A Virus, H9N2 Subtype - immunologyen_HK
dc.subject.meshInfluenza Vaccines - immunology - supply & distributionen_HK
dc.subject.meshInfluenza in Birds - epidemiology - prevention & control - transmission - virologyen_HK
dc.subject.meshInfluenza, Human - epidemiology - prevention & control - transmission - virologyen_HK
dc.titleH5N1 outbreaks and enzootic influenzaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1080-6040&volume=12&issue=1&spage=3&epage=8&date=2006&atitle=H5N1+outbreaks+and+enzootic+influenzaen_HK
dc.identifier.emailPeiris, M: malik@hkucc.hku.hken_HK
dc.identifier.emailChen, H: hlchen@hku.hken_HK
dc.identifier.emailGuan, Y: yguan@hkucc.hku.hken_HK
dc.identifier.authorityPeiris, M=rp00410en_HK
dc.identifier.authorityChen, H=rp00383en_HK
dc.identifier.authorityGuan, Y=rp00397en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid16494709en_HK
dc.identifier.scopuseid_2-s2.0-31344446643en_HK
dc.identifier.hkuros116506en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-31344446643&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume12en_HK
dc.identifier.issue1en_HK
dc.identifier.spage3en_HK
dc.identifier.epage8en_HK
dc.identifier.isiWOS:000234419700002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWebster, RG=36048363100en_HK
dc.identifier.scopusauthoridPeiris, M=7005486823en_HK
dc.identifier.scopusauthoridChen, H=26643315400en_HK
dc.identifier.scopusauthoridGuan, Y=7202924055en_HK

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