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Article: Reduction of platelet transfusion-associated sepsis by short-term bacterial culture
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TitleReduction of platelet transfusion-associated sepsis by short-term bacterial culture
 
AuthorsLiu, HW1
Yuen, KY
Cheng, TSY
Lee, KB
Chua, EKM
Ho, PL
Lin, CK
 
Issue Date1999
 
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/VOX
 
CitationVox Sanguinis, 1999, v. 77 n. 1, p. 1-5 [How to Cite?]
DOI: http://dx.doi.org/10.1159/000031066
 
AbstractBackground and Objectives: There is as yet no suitable routine laboratory test for a blood transfusion service to detect bacterial contamination in platelets. This study evaluates the effectiveness and the applicability of short-term bacterial culture for such a purpose. Materials and Methods: Samples from 5-unit platelet pools were inoculated into an aerobic culture bottle, then monitored for 48 h at 35°C in an automated monitoring and detection system. Results: 26,210 whole-blood-derived platelet components were tested, of which 14 (0.053%) platelet units were found to be contaminated. In addition, nine of the associated red cell units and 4 fresh-frozen plasma units grew the same organisms on culture. Conclusion: Short-duration bacterial culture by an automated system is effective and suitable for routine screening in a regional transfusion center.
 
ISSN0042-9007
2012 Impact Factor: 2.847
2012 SCImago Journal Rankings: 0.877
 
DOIhttp://dx.doi.org/10.1159/000031066
 
ISI Accession Number IDWOS:000082415000001
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorLiu, HW
 
dc.contributor.authorYuen, KY
 
dc.contributor.authorCheng, TSY
 
dc.contributor.authorLee, KB
 
dc.contributor.authorChua, EKM
 
dc.contributor.authorHo, PL
 
dc.contributor.authorLin, CK
 
dc.date.accessioned2010-09-06T07:48:48Z
 
dc.date.available2010-09-06T07:48:48Z
 
dc.date.issued1999
 
dc.description.abstractBackground and Objectives: There is as yet no suitable routine laboratory test for a blood transfusion service to detect bacterial contamination in platelets. This study evaluates the effectiveness and the applicability of short-term bacterial culture for such a purpose. Materials and Methods: Samples from 5-unit platelet pools were inoculated into an aerobic culture bottle, then monitored for 48 h at 35°C in an automated monitoring and detection system. Results: 26,210 whole-blood-derived platelet components were tested, of which 14 (0.053%) platelet units were found to be contaminated. In addition, nine of the associated red cell units and 4 fresh-frozen plasma units grew the same organisms on culture. Conclusion: Short-duration bacterial culture by an automated system is effective and suitable for routine screening in a regional transfusion center.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationVox Sanguinis, 1999, v. 77 n. 1, p. 1-5 [How to Cite?]
DOI: http://dx.doi.org/10.1159/000031066
 
dc.identifier.doihttp://dx.doi.org/10.1159/000031066
 
dc.identifier.epage5
 
dc.identifier.hkuros50548
 
dc.identifier.isiWOS:000082415000001
 
dc.identifier.issn0042-9007
2012 Impact Factor: 2.847
2012 SCImago Journal Rankings: 0.877
 
dc.identifier.issue1
 
dc.identifier.openurl
 
dc.identifier.pmid10474083
 
dc.identifier.scopuseid_2-s2.0-0032817268
 
dc.identifier.spage1
 
dc.identifier.urihttp://hdl.handle.net/10722/78953
 
dc.identifier.volume77
 
dc.languageeng
 
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/VOX
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofVox Sanguinis
 
dc.relation.referencesReferences in Scopus
 
dc.rightsVox Sanguinis. Copyright © Blackwell Publishing Ltd.
 
dc.subject.meshColony-Forming Units Assay
 
dc.subject.meshHumans
 
dc.subject.meshPlatelet Transfusion - adverse effects
 
dc.subject.meshPopulation Surveillance
 
dc.subject.meshSensitivity and Specificity
 
dc.subject.meshSepsis - microbiology
 
dc.subject.meshTime Factors
 
dc.titleReduction of platelet transfusion-associated sepsis by short-term bacterial culture
 
dc.typeArticle
 
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Author Affiliations
  1. Hong Kong Red Cross Blood T. S.