Article: Molecular diversity of coronaviruses in bats
| Title | Molecular diversity of coronaviruses in bats |
|---|---|
| Authors | Woo, PCY1 Lau, SKP1 Li, KSM1 Poon, RWS1 Wong, BHL1 Tsoi, Hw1 Yip, BCK1 Huang, Y1 Chan, Kh1 Yuen, Ky1 |
| Issue Date | 2006 |
| Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/yviro |
| Citation | Virology, 2006, v. 351 n. 1, p. 180-187 [How to Cite?] DOI: http://dx.doi.org/10.1016/j.virol.2006.02.041 |
| Abstract | The existence of coronaviruses in bats is unknown until the recent discovery of bat-SARS-CoV in Chinese horseshoe bats and a novel group 1 coronavirus in other bat species. Among 309 bats of 13 species captured from 20 different locations in rural areas of Hong Kong over a 16-month period, coronaviruses were amplified from anal swabs of 37 (12%) bats by RT-PCR. Phylogenetic analysis of RNA-dependent-RNA-polymerase (pol) and helicase genes revealed six novel coronaviruses from six different bat species, in addition to the two previously described coronaviruses. Among the six novel coronaviruses, four were group 1 coronaviruses (bat-CoV HKU2 from Chinese horseshoe bat, bat-CoV HKU6 from rickett's big-footed bat, bat-CoV HKU7 from greater bent-winged bat and bat-CoV HKU8 from lesser bent-winged bat) and two were group 2 coronaviruses (bat-CoV HKU4 from lesser bamboo bats and bat-CoV HKU5 from Japanese pipistrelles). An astonishing diversity of coronaviruses was observed in bats. © 2006 Elsevier Inc. All rights reserved. |
| ISSN | 0042-6822 2011 Impact Factor: 3.351 2011 SCImago Journal Rankings: 0.355 |
| DOI | http://dx.doi.org/10.1016/j.virol.2006.02.041 |
| ISI Accession Number ID | WOS:000239319900017 |
| References | References in Scopus |
| dc.contributor.author | Woo, PCY |
|---|---|
| dc.contributor.author | Lau, SKP |
| dc.contributor.author | Li, KSM |
| dc.contributor.author | Poon, RWS |
| dc.contributor.author | Wong, BHL |
| dc.contributor.author | Tsoi, Hw |
| dc.contributor.author | Yip, BCK |
| dc.contributor.author | Huang, Y |
| dc.contributor.author | Chan, Kh |
| dc.contributor.author | Yuen, Ky |
| dc.date.accessioned | 2010-09-06T07:48:39Z |
| dc.date.available | 2010-09-06T07:48:39Z |
| dc.date.issued | 2006 |
| dc.description.abstract | The existence of coronaviruses in bats is unknown until the recent discovery of bat-SARS-CoV in Chinese horseshoe bats and a novel group 1 coronavirus in other bat species. Among 309 bats of 13 species captured from 20 different locations in rural areas of Hong Kong over a 16-month period, coronaviruses were amplified from anal swabs of 37 (12%) bats by RT-PCR. Phylogenetic analysis of RNA-dependent-RNA-polymerase (pol) and helicase genes revealed six novel coronaviruses from six different bat species, in addition to the two previously described coronaviruses. Among the six novel coronaviruses, four were group 1 coronaviruses (bat-CoV HKU2 from Chinese horseshoe bat, bat-CoV HKU6 from rickett's big-footed bat, bat-CoV HKU7 from greater bent-winged bat and bat-CoV HKU8 from lesser bent-winged bat) and two were group 2 coronaviruses (bat-CoV HKU4 from lesser bamboo bats and bat-CoV HKU5 from Japanese pipistrelles). An astonishing diversity of coronaviruses was observed in bats. © 2006 Elsevier Inc. All rights reserved. |
| dc.description.nature | Link_to_subscribed_fulltext |
| dc.identifier.citation | Virology, 2006, v. 351 n. 1, p. 180-187 [How to Cite?] DOI: http://dx.doi.org/10.1016/j.virol.2006.02.041 |
| dc.identifier.doi | http://dx.doi.org/10.1016/j.virol.2006.02.041 |
| dc.identifier.epage | 187 |
| dc.identifier.hkuros | 123213 |
| dc.identifier.isi | WOS:000239319900017 |
| dc.identifier.issn | 0042-6822 2011 Impact Factor: 3.351 2011 SCImago Journal Rankings: 0.355 |
| dc.identifier.issue | 1 |
| dc.identifier.openurl | ![]() |
| dc.identifier.pmid | 16647731 |
| dc.identifier.scopus | eid_2-s2.0-33745784140 |
| dc.identifier.spage | 180 |
| dc.identifier.uri | http://hdl.handle.net/10722/78940 |
| dc.identifier.volume | 351 |
| dc.language | eng |
| dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/yviro |
| dc.publisher.place | United States |
| dc.relation.ispartof | Virology |
| dc.relation.references | References in Scopus |
| dc.subject.mesh | Animals |
| dc.subject.mesh | Chiroptera - virology |
| dc.subject.mesh | Coronaviridae - classification - genetics - isolation & purification |
| dc.subject.mesh | Genetic Variation - genetics |
| dc.subject.mesh | Molecular Epidemiology |
| dc.subject.mesh | Molecular Sequence Data |
| dc.subject.mesh | Phylogeny |
| dc.title | Molecular diversity of coronaviruses in bats |
| dc.type | Article |
Author Affiliations
- The University of Hong Kong


