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Article: Association of human herpesvirus 7 with cytomegalovirus disease in renal transplant recipients

TitleAssociation of human herpesvirus 7 with cytomegalovirus disease in renal transplant recipients
Authors
Issue Date2000
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.transplantjournal.com
Citation
Transplantation, 2000, v. 70 n. 1, p. 213-216 How to Cite?
AbstractBackground. Recent studies have linked human herpesviruses 6 (HHV-6) and 7 (HHV-7) with posttransplant cytomegalovirus (CMV) disease. Methods. Thirty- seven renal transplant recipients were monitored weekly for CMV, HHV-6, and HHV-7 DNA and serological responses for 12 weeks after transplantation. Plasma CMV load and the occurrence of CMV disease was related to HHV-6 and -7 detection. Results. CMV disease was identified in 12 patients. In a logistic regression analysis, factors significantly associated with CMV disease were the detection of HHV-7 DNA in peripheral blood leucocytes and donor-recipient CMV serostatus. Patients with detectable HHV-7 DNA had significantly higher peak plasma CMV loads (P = 0.01). Conclusions. An association was found between HHV-7, but not HHV-6, DNA detection and CMV disease, suggesting a possible role of HHV-7 in its pathogenesis.
Persistent Identifierhttp://hdl.handle.net/10722/78844
ISSN
2015 Impact Factor: 3.69
2015 SCImago Journal Rankings: 1.699
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorTong, CYWen_HK
dc.contributor.authorBakran, Aen_HK
dc.contributor.authorWilliams, Hen_HK
dc.contributor.authorCheung, CYen_HK
dc.contributor.authorPeiris, JSMen_HK
dc.date.accessioned2010-09-06T07:47:30Z-
dc.date.available2010-09-06T07:47:30Z-
dc.date.issued2000en_HK
dc.identifier.citationTransplantation, 2000, v. 70 n. 1, p. 213-216en_HK
dc.identifier.issn0041-1337en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78844-
dc.description.abstractBackground. Recent studies have linked human herpesviruses 6 (HHV-6) and 7 (HHV-7) with posttransplant cytomegalovirus (CMV) disease. Methods. Thirty- seven renal transplant recipients were monitored weekly for CMV, HHV-6, and HHV-7 DNA and serological responses for 12 weeks after transplantation. Plasma CMV load and the occurrence of CMV disease was related to HHV-6 and -7 detection. Results. CMV disease was identified in 12 patients. In a logistic regression analysis, factors significantly associated with CMV disease were the detection of HHV-7 DNA in peripheral blood leucocytes and donor-recipient CMV serostatus. Patients with detectable HHV-7 DNA had significantly higher peak plasma CMV loads (P = 0.01). Conclusions. An association was found between HHV-7, but not HHV-6, DNA detection and CMV disease, suggesting a possible role of HHV-7 in its pathogenesis.en_HK
dc.languageengen_HK
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.transplantjournal.comen_HK
dc.relation.ispartofTransplantationen_HK
dc.rightsTransplantation. Copyright © Lippincott Williams & Wilkins.en_HK
dc.titleAssociation of human herpesvirus 7 with cytomegalovirus disease in renal transplant recipientsen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0041-1337&volume=70&spage=213&epage=216&date=2000&atitle=Association+of+human+herpesvirus-7+with+cytomegalovirus+disease+in+renal+transplant+recipients.en_HK
dc.identifier.emailCheung, CY: chungey@hkucc.hku.hken_HK
dc.identifier.emailPeiris, JSM: malik@hkucc.hku.hken_HK
dc.identifier.authorityCheung, CY=rp00404en_HK
dc.identifier.authorityPeiris, JSM=rp00410en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.pmid10919606-
dc.identifier.scopuseid_2-s2.0-0034662215en_HK
dc.identifier.hkuros60550en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034662215&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume70en_HK
dc.identifier.issue1en_HK
dc.identifier.spage213en_HK
dc.identifier.epage216en_HK
dc.identifier.isiWOS:000088496100042-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridTong, CYW=35294089600en_HK
dc.identifier.scopusauthoridBakran, A=7004639540en_HK
dc.identifier.scopusauthoridWilliams, H=7402821385en_HK
dc.identifier.scopusauthoridCheung, CY=7202061836en_HK
dc.identifier.scopusauthoridPeiris, JSM=7005486823en_HK

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