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Article: Vitamin D inadequacy in postmenopausal women in Eastern Asia

TitleVitamin D inadequacy in postmenopausal women in Eastern Asia
Authors
Issue Date2008
PublisherLibrapharm Ltd.
Citation
Current Medical Research And Opinion, 2008, v. 24 n. 1, p. 99-106 How to Cite?
AbstractObjective: To review data on the prevalence of vitamin D inadequacy and its causes in postmenopausal women in Eastern Asia. Research design and method: Data were obtained from the published biomedical literature as well as abstracts and posters presented at scientific meetings. Using MEDLINE, EMBASE and BIOSIS databases (to July 2007), epidemiological studies were identified using the search terms: 'human', 'vitamin D', 'vitamin D deficiency', 'vitamin D inadequacy', 'vitamin D insufficiency' and 'hypovitaminosis D', 'osteomalacia' and 'osteoporosis'. Additional references were also identified from the bibliographies of published articles. Results: The prevalence of vitamin D inadequacy in studies of postmenopausal women (ambulatory or with osteoporosis or related musculoskeletal disorders) in Eastern Asia ranged from 0 to 92%, depending on the cut-off level of serum 25-hydroxychotecalciferol [25(OH)D] that was applied (range ≤6-35 ng/mL [≤ 15-87 nmol/L]). One large international study found that 71% of postmenopausal women with osteoporosis in Eastern Asia had vitamin D inadequacy, defined as serum levels of 25(OH)D < 30 ng/mL (75 nmol/L). Prevalence rates using this cut-off level were 47% in Thailand, 49% in Malaysia, 90% in Japan and 92% in South Korea. High prevalences of vitamin D inadequacy were evident in two studies using a lower 25(OH)D level cut-off value of < 12 ng/mL (30 nmol/L) - 21% in China and 57% in South Korea. Dietary deficiency and inadequate exposure or reactivity to sunlight (due to lifestyle choices, cultural customs and/or aging) were identified as important risk factors for vitamin D inadequacy. Conclusions: Non-uniform, epidemiological studies indicate a high prevalence of vitamin D inadequacy in postmenopausal women in Eastern Asia. Recommended remedial approaches are education campaigns and broad-based provision of vitamin D supplementation. © 2008 Librapharm Limited All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/78619
ISSN
2015 Impact Factor: 2.643
2015 SCImago Journal Rankings: 0.896
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorLim, SKen_HK
dc.contributor.authorKung, AWCen_HK
dc.contributor.authorSompongse, Sen_HK
dc.contributor.authorSoontrapa, Sen_HK
dc.contributor.authorTsai, KSen_HK
dc.date.accessioned2010-09-06T07:44:53Z-
dc.date.available2010-09-06T07:44:53Z-
dc.date.issued2008en_HK
dc.identifier.citationCurrent Medical Research And Opinion, 2008, v. 24 n. 1, p. 99-106en_HK
dc.identifier.issn0300-7995en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78619-
dc.description.abstractObjective: To review data on the prevalence of vitamin D inadequacy and its causes in postmenopausal women in Eastern Asia. Research design and method: Data were obtained from the published biomedical literature as well as abstracts and posters presented at scientific meetings. Using MEDLINE, EMBASE and BIOSIS databases (to July 2007), epidemiological studies were identified using the search terms: 'human', 'vitamin D', 'vitamin D deficiency', 'vitamin D inadequacy', 'vitamin D insufficiency' and 'hypovitaminosis D', 'osteomalacia' and 'osteoporosis'. Additional references were also identified from the bibliographies of published articles. Results: The prevalence of vitamin D inadequacy in studies of postmenopausal women (ambulatory or with osteoporosis or related musculoskeletal disorders) in Eastern Asia ranged from 0 to 92%, depending on the cut-off level of serum 25-hydroxychotecalciferol [25(OH)D] that was applied (range ≤6-35 ng/mL [≤ 15-87 nmol/L]). One large international study found that 71% of postmenopausal women with osteoporosis in Eastern Asia had vitamin D inadequacy, defined as serum levels of 25(OH)D < 30 ng/mL (75 nmol/L). Prevalence rates using this cut-off level were 47% in Thailand, 49% in Malaysia, 90% in Japan and 92% in South Korea. High prevalences of vitamin D inadequacy were evident in two studies using a lower 25(OH)D level cut-off value of < 12 ng/mL (30 nmol/L) - 21% in China and 57% in South Korea. Dietary deficiency and inadequate exposure or reactivity to sunlight (due to lifestyle choices, cultural customs and/or aging) were identified as important risk factors for vitamin D inadequacy. Conclusions: Non-uniform, epidemiological studies indicate a high prevalence of vitamin D inadequacy in postmenopausal women in Eastern Asia. Recommended remedial approaches are education campaigns and broad-based provision of vitamin D supplementation. © 2008 Librapharm Limited All rights reserved.en_HK
dc.languageengen_HK
dc.publisherLibrapharm Ltd.en_HK
dc.relation.ispartofCurrent Medical Research and Opinionen_HK
dc.subject.meshFar East - epidemiologyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMalaysia - epidemiologyen_HK
dc.subject.meshMusculoskeletal Diseases - epidemiology - etiologyen_HK
dc.subject.meshOsteoporosis, Postmenopausal - epidemiology - etiologyen_HK
dc.subject.meshPostmenopause - blooden_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshThailand - epidemiologyen_HK
dc.subject.meshVitamin D Deficiency - complications - epidemiologyen_HK
dc.titleVitamin D inadequacy in postmenopausal women in Eastern Asiaen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0300-7995&volume=24&spage=99&epage=106&date=2008&atitle=Vitamin+D+inadequacy+in+postmenopausal+women+in+eastern+Asiaen_HK
dc.identifier.emailKung, AWC:awckung@hku.hken_HK
dc.identifier.authorityKung, AWC=rp00368en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1185/030079908X253429en_HK
dc.identifier.pmid18028585-
dc.identifier.scopuseid_2-s2.0-38549092141en_HK
dc.identifier.hkuros142099en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38549092141&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume24en_HK
dc.identifier.issue1en_HK
dc.identifier.spage99en_HK
dc.identifier.epage106en_HK
dc.identifier.isiWOS:000252694300011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridLim, SK=7404080753en_HK
dc.identifier.scopusauthoridKung, AWC=7102322339en_HK
dc.identifier.scopusauthoridSompongse, S=23478807900en_HK
dc.identifier.scopusauthoridSoontrapa, S=6701392129en_HK
dc.identifier.scopusauthoridTsai, KS=7201566015en_HK
dc.identifier.citeulike2156555-

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