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Article: Cardiac amyloidosis - Experience in a tertiary cardiac referral centre

TitleCardiac amyloidosis - Experience in a tertiary cardiac referral centre
Authors
Issue Date2008
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
Citation
International Journal Of Cardiology, 2008, v. 124 n. 2, p. 264-266 How to Cite?
AbstractAmyloidosis is an uncommon systemic disease characterized by deposition of insoluble fibrillar protein in different organs and the prognosis is poor if the heart is involved. Experience with management of cardiac amyloidosis is difficult because of its rare occurrence, late presentation and ineffective treatment. Since 1995, we have encountered and prospectively followed up 16 cases of cardiac amyloidosis in our cardiac centre. We believe this is the largest series of cardiac amyloidosis reported in Chinese patients. The 1-year, 3-year and 5-year survival rates were 40%, 25% and 17%, respectively. The major cause of death was cardiac-related. Those patients with overt heart failure or with untreated amyloidosis had a dismal prognosis (mean survival of 2.2 months and 3.5 months, respectively). Those who received specific treatment for the underlying amyloidosis had a better outcome with an average survival of 33.4 months. © 2007 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/78597
ISSN
2015 Impact Factor: 4.638
2015 SCImago Journal Rankings: 1.513
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorChau, EMCen_HK
dc.contributor.authorChow, WHen_HK
dc.contributor.authorWang, Een_HK
dc.contributor.authorKwong, YLen_HK
dc.date.accessioned2010-09-06T07:44:38Z-
dc.date.available2010-09-06T07:44:38Z-
dc.date.issued2008en_HK
dc.identifier.citationInternational Journal Of Cardiology, 2008, v. 124 n. 2, p. 264-266en_HK
dc.identifier.issn0167-5273en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78597-
dc.description.abstractAmyloidosis is an uncommon systemic disease characterized by deposition of insoluble fibrillar protein in different organs and the prognosis is poor if the heart is involved. Experience with management of cardiac amyloidosis is difficult because of its rare occurrence, late presentation and ineffective treatment. Since 1995, we have encountered and prospectively followed up 16 cases of cardiac amyloidosis in our cardiac centre. We believe this is the largest series of cardiac amyloidosis reported in Chinese patients. The 1-year, 3-year and 5-year survival rates were 40%, 25% and 17%, respectively. The major cause of death was cardiac-related. Those patients with overt heart failure or with untreated amyloidosis had a dismal prognosis (mean survival of 2.2 months and 3.5 months, respectively). Those who received specific treatment for the underlying amyloidosis had a better outcome with an average survival of 33.4 months. © 2007 Elsevier Ireland Ltd. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcarden_HK
dc.relation.ispartofInternational Journal of Cardiologyen_HK
dc.rightsInternational journal of cardiology. Copyright © Elsevier Ireland Ltd.en_HK
dc.subject.meshAdulten_HK
dc.subject.meshAgeden_HK
dc.subject.meshAmyloid - metabolismen_HK
dc.subject.meshAmyloidosis - diagnosis - epidemiology - therapyen_HK
dc.subject.meshBiopsy, Needleen_HK
dc.subject.meshCardiomyopathies - diagnosis - epidemiology - therapyen_HK
dc.subject.meshCombined Modality Therapyen_HK
dc.subject.meshEchocardiographyen_HK
dc.subject.meshElectrocardiographyen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHeart Catheterizationen_HK
dc.subject.meshHeart Transplantationen_HK
dc.subject.meshHong Kong - epidemiologyen_HK
dc.subject.meshHospitals, Specialen_HK
dc.subject.meshHumansen_HK
dc.subject.meshImmunohistochemistryen_HK
dc.subject.meshMaleen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshPrevalenceen_HK
dc.subject.meshPrognosisen_HK
dc.subject.meshRetrospective Studiesen_HK
dc.subject.meshRisk Assessmenten_HK
dc.subject.meshSeverity of Illness Indexen_HK
dc.subject.meshSurvival Analysisen_HK
dc.titleCardiac amyloidosis - Experience in a tertiary cardiac referral centreen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0167-5273&volume=124&issue=2&spage=264&epage=6&date=2008&atitle=Cardiac+amyloidosis+-+experience+in+a+tertiary+cardiac+referral+centreen_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ijcard.2006.12.041en_HK
dc.identifier.pmid17383027-
dc.identifier.scopuseid_2-s2.0-38649127217en_HK
dc.identifier.hkuros146355en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-38649127217&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume124en_HK
dc.identifier.issue2en_HK
dc.identifier.spage264en_HK
dc.identifier.epage266en_HK
dc.identifier.isiWOS:000254825100028-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridChau, EMC=8081027500en_HK
dc.identifier.scopusauthoridChow, WH=7402281062en_HK
dc.identifier.scopusauthoridWang, E=7403414620en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK

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