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Article: Asia-Pacific consensus on the management of gastroesophageal reflux disease: Update

TitleAsia-Pacific consensus on the management of gastroesophageal reflux disease: Update
Authors
Issue Date2008
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
Journal Of Gastroenterology And Hepatology, 2008, v. 23 n. 1, p. 8-22 How to Cite?
AbstractBackground and Aims: Since the publication of the Asia-Pacific GERD consensus in 2004, more data concerning the epidemiology and management of gastroesophageal reflux disease (GERD) have emerged. An evidence based review and update was needed. Methods: A multidisciplinary group developed consensus statements using the Delphi approach. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Results: GERD is increasing in frequency in Asia. Risk factors include older age, male sex, race, family history, higher socioeconomic status, increased body mass index, and smoking. Symptomatic response to a proton pump inhibitor (PPI) test is diagnostic in patients with typical symptoms if alarm symptoms are absent. A negative pH study off therapy excludes GERD if a PPI test fails. The role for narrow band imaging, capsule endoscopy, and wireless pH monitoring has not yet been undefined. Diagnostic strategies in Asia must consider coexistent gastric cancer and peptic ulcer. Weight loss and elevation of head of bed improve reflux symptoms. PPIs are the most effective medical treatment. On-demand therapy is appropriate for nonerosive reflux disease (NERD) patients. Patients with chronic cough, laryngitis, and typical GERD symptoms should be offered twice daily PPI therapy after excluding non-GERD etiologies. Fundoplication could be offered to GERD patients when an experienced surgeon is available. Endoscopic treatment of GERD should not be offered outside clinical trials. Conclusions: Further studies are needed to clarify the role of newer diagnostic modalities and endoscopic therapy. Diagnostic strategies for GERD in Asia must consider coexistent gastric cancer and peptic ulcer. PPIs remain the cornerstone of therapy. © 2008 The Authors.
Persistent Identifierhttp://hdl.handle.net/10722/78431
ISSN
2014 Impact Factor: 3.504
2014 SCImago Journal Rankings: 1.128
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorFock, KMen_HK
dc.contributor.authorTalley, NJen_HK
dc.contributor.authorFass, Ren_HK
dc.contributor.authorGoh, KLen_HK
dc.contributor.authorKatelaris, Pen_HK
dc.contributor.authorHunt, Ren_HK
dc.contributor.authorHongo, Men_HK
dc.contributor.authorAng, TLen_HK
dc.contributor.authorHoltmann, Gen_HK
dc.contributor.authorNandurkar, Sen_HK
dc.contributor.authorLin, SRen_HK
dc.contributor.authorWong, BCYen_HK
dc.contributor.authorChan, FKLen_HK
dc.contributor.authorRani, AAen_HK
dc.contributor.authorBak, YTen_HK
dc.contributor.authorSollano, Jen_HK
dc.contributor.authorHo, LKYen_HK
dc.contributor.authorManatsathit, Sen_HK
dc.date.accessioned2010-09-06T07:42:49Z-
dc.date.available2010-09-06T07:42:49Z-
dc.date.issued2008en_HK
dc.identifier.citationJournal Of Gastroenterology And Hepatology, 2008, v. 23 n. 1, p. 8-22en_HK
dc.identifier.issn0815-9319en_HK
dc.identifier.urihttp://hdl.handle.net/10722/78431-
dc.description.abstractBackground and Aims: Since the publication of the Asia-Pacific GERD consensus in 2004, more data concerning the epidemiology and management of gastroesophageal reflux disease (GERD) have emerged. An evidence based review and update was needed. Methods: A multidisciplinary group developed consensus statements using the Delphi approach. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Results: GERD is increasing in frequency in Asia. Risk factors include older age, male sex, race, family history, higher socioeconomic status, increased body mass index, and smoking. Symptomatic response to a proton pump inhibitor (PPI) test is diagnostic in patients with typical symptoms if alarm symptoms are absent. A negative pH study off therapy excludes GERD if a PPI test fails. The role for narrow band imaging, capsule endoscopy, and wireless pH monitoring has not yet been undefined. Diagnostic strategies in Asia must consider coexistent gastric cancer and peptic ulcer. Weight loss and elevation of head of bed improve reflux symptoms. PPIs are the most effective medical treatment. On-demand therapy is appropriate for nonerosive reflux disease (NERD) patients. Patients with chronic cough, laryngitis, and typical GERD symptoms should be offered twice daily PPI therapy after excluding non-GERD etiologies. Fundoplication could be offered to GERD patients when an experienced surgeon is available. Endoscopic treatment of GERD should not be offered outside clinical trials. Conclusions: Further studies are needed to clarify the role of newer diagnostic modalities and endoscopic therapy. Diagnostic strategies for GERD in Asia must consider coexistent gastric cancer and peptic ulcer. PPIs remain the cornerstone of therapy. © 2008 The Authors.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGHen_HK
dc.relation.ispartofJournal of Gastroenterology and Hepatologyen_HK
dc.subject.meshAsiaen_HK
dc.subject.meshGastroesophageal Reflux - diagnosis - epidemiology - therapyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshPacific Islandsen_HK
dc.subject.meshProton Pump Inhibitors - therapeutic useen_HK
dc.titleAsia-Pacific consensus on the management of gastroesophageal reflux disease: Updateen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0815-9319&volume=23&issue=1&spage=8&epage=22&date=2008&atitle=Asia-Pacific+consensus+on+the+management+of+gastroesophageal+reflux+disease:+updateen_HK
dc.identifier.emailWong, BCY:bcywong@hku.hken_HK
dc.identifier.authorityWong, BCY=rp00429en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1440-1746.2007.05249.xen_HK
dc.identifier.pmid18171339-
dc.identifier.scopuseid_2-s2.0-37249000857en_HK
dc.identifier.hkuros158945en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-37249000857&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume23en_HK
dc.identifier.issue1en_HK
dc.identifier.spage8en_HK
dc.identifier.epage22en_HK
dc.identifier.isiWOS:000251671000005-
dc.publisher.placeAustraliaen_HK
dc.identifier.scopusauthoridFock, KM=7006721062en_HK
dc.identifier.scopusauthoridTalley, NJ=36045241200en_HK
dc.identifier.scopusauthoridFass, R=7103304557en_HK
dc.identifier.scopusauthoridGoh, KL=7201860992en_HK
dc.identifier.scopusauthoridKatelaris, P=7005727567en_HK
dc.identifier.scopusauthoridHunt, R=7401608004en_HK
dc.identifier.scopusauthoridHongo, M=35901025600en_HK
dc.identifier.scopusauthoridAng, TL=8604912300en_HK
dc.identifier.scopusauthoridHoltmann, G=7005897517en_HK
dc.identifier.scopusauthoridNandurkar, S=6602493288en_HK
dc.identifier.scopusauthoridLin, SR=7407614017en_HK
dc.identifier.scopusauthoridWong, BCY=7402023340en_HK
dc.identifier.scopusauthoridChan, FKL=7202586434en_HK
dc.identifier.scopusauthoridRani, AA=7006676360en_HK
dc.identifier.scopusauthoridBak, YT=7003401059en_HK
dc.identifier.scopusauthoridSollano, J=6602099153en_HK
dc.identifier.scopusauthoridHo, LKY=36784944700en_HK
dc.identifier.scopusauthoridManatsathit, S=6602759678en_HK
dc.identifier.citeulike2136884-

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